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List of works by Clemens Löwik

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Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonist

scientific article
Sclerostin is a delayed secreted product of osteocytes that inhibits bone formation

scientific article
The clinical use of indocyanine green as a near-infrared fluorescent contrast agent for image-guided oncologic surgery

scientific article published on 14 April 2011
BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis

scientific article
The tumor suppressor Smad4 is required for transforming growth factor beta-induced epithelial to mesenchymal transition and bone metastasis of breast cancer cells

scientific article published on February 2006
Endostatin inhibits VEGF-induced endothelial cell migration and tumor growth independently of zinc binding

scientific article published on August 1999
Bone morphogenetic proteins stimulate angiogenesis through osteoblast-derived vascular endothelial growth factor A.

scientific article published on April 2002
Murine malaria parasite sequestration: CD36 is the major receptor, but cerebral pathology is unlinked to sequestration

scientific article
Mesenchymal stem cells promote engraftment of human umbilical cord blood-derived CD34(+) cells in NOD/SCID mice

scientific article
Farnesyl pyrophosphate synthase is the molecular target of nitrogen-containing bisphosphonates

scientific article published in October 1999
Expression of vascular endothelial growth factors and their receptors during osteoblast differentiation

scientific article
Sclerostin: current knowledge and future perspectives

scientific article
SOST/sclerostin, an osteocyte-derived negative regulator of bone formation

scientific article
Visualisation and quantitative analysis of the rodent malaria liver stage by real time imaging

scientific article
In vivo imaging of transcriptionally active estrogen receptors.

scientific article published on 16 December 2002
Parathyroid hormone (PTH) and PTH-like protein (PLP) stimulate interleukin-6 production by osteogenic cells: a possible role of interleukin-6 in osteoclastogenesis

scientific article published on 01 August 1989
Peroxisome proliferator-activated receptor gamma (PPARgamma ) as a molecular target for the soy phytoestrogen genistein

scientific article (publication date: 10 January 2003)
Optical image-guided surgery--where do we stand?

scientific article published on April 2011
Bisphosphonates inhibit the adhesion of breast cancer cells to bone matrices in vitro

scientific article published on August 1996
Wnt but not BMP signaling is involved in the inhibitory action of sclerostin on BMP-stimulated bone formation

scientific article
Toward optimization of imaging system and lymphatic tracer for near-infrared fluorescent sentinel lymph node mapping in breast cancer

scientific article
Optical imaging of cancer metastasis to bone marrow: a mouse model of minimal residual disease

scientific article published on March 2002
Near‐infrared fluorescence‐guided resection of colorectal liver metastases

scientific article published on June 21, 2013
BMP7, a putative regulator of epithelial homeostasis in the human prostate, is a potent inhibitor of prostate cancer bone metastasis in vivo

scientific article
Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer

scientific article
Exposure of KS483 cells to estrogen enhances osteogenesis and inhibits adipogenesis

scientific article published on March 2002
CD40-targeted dendritic cell delivery of PLGA-nanoparticle vaccines induce potent anti-tumor responses

scientific article published on November 26, 2014
Distinct modes of inhibition by sclerostin on bone morphogenetic protein and Wnt signaling pathways

scientific article
Osteocyte-derived sclerostin inhibits bone formation: its role in bone morphogenetic protein and Wnt signaling.

scientific article published on February 2008
Downregulation of Wnt signaling by increased expression of Dickkopf-1 and -2 is a prerequisite for late-stage osteoblast differentiation of KS483 cells

scientific article published on 26 June 2005
Sclerostin in Mineralized Matrices and van Buchem Disease

scientific article published on 01 June 2009
The role of geranylgeranylation in bone resorption and its suppression by bisphosphonates in fetal bone explants in vitro: A clue to the mechanism of action of nitrogen-containing bisphosphonates

scientific article
Migration and phenotypic transformation of osteoclast precursors into mature osteoclasts: the effect of a bisphosphonate

scientific article
Optical image-guided cancer surgery: challenges and limitations

scientific article published on 14 May 2013
Nitrogen-containing bisphosphonates inhibit isopentenyl pyrophosphate isomerase/farnesyl pyrophosphate synthase activity with relative potencies corresponding to their antiresorptive potencies in vitro and in vivo

scientific article published in February 1999
Molecular imaging of tumor angiogenesis using alphavbeta3-integrin targeted multimodal quantum dots

scientific article
Interleukin-17: A new bone acting cytokine in vitro

scientific article published on September 1999
Bone mineral density in sclerosteosis; affected individuals and gene carriers

scientific article
Differentiating the mechanisms of antiresorptive action of nitrogen containing bisphosphonates

scientific article published on November 1, 2003
Nasal vaccination with N-trimethyl chitosan and PLGA based nanoparticles: nanoparticle characteristics determine quality and strength of the antibody response in mice against the encapsulated antigen

scientific article published on 16 July 2010
Inducible production of nitric oxide in osteoblast-like cells and in fetal mouse bone explants is associated with suppression of osteoclastic bone resorption

scientific article
Hedgehog stimulates only osteoblastic differentiation of undifferentiated KS483 cells

scientific article published on December 2003
VEGF and inhibitors of TGFbeta type-I receptor kinase synergistically promote blood-vessel formation by inducing alpha5-integrin expression.

scientific article published on 25 August 2009
Randomized, double-blind comparison of indocyanine green with or without albumin premixing for near-infrared fluorescence imaging of sentinel lymph nodes in breast cancer patients

scientific article published on March 2011
Differential expression of estrogen receptors alpha and beta mRNA during differentiation of human osteoblast SV-HFO cells.

scientific article published on November 1997
Whole-body optical imaging in animal models to assess cancer development and progression

scientific article published on June 2007
Randomized Comparison of Near-infrared Fluorescence Imaging Using Indocyanine Green and 99m Technetium With or Without Patent Blue for the Sentinel Lymph Node Procedure in Breast Cancer Patients

scientific article published on July 3, 2012
Expression of Indian hedgehog, parathyroid hormone-related protein, and their receptors in the postnatal growth plate of the rat: evidence for a locally acting growth restraining feedback loop after birth

scientific article published on 01 June 2000
A two-receptor model for the action of parathyroid hormone on osteoblasts: a role for intracellular free calcium and cAMP.

scientific article published in August 1985
Bisphosphonates suppress bone resorption by a direct effect on early osteoclast precursors without affecting the osteoclastogenic capacity of osteogenic cells: the role of protein geranylgeranylation in the action of nitrogen-containing bisphosphona

scientific article published in January 2002

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