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List of works by James C. Iatridis

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Mechanical conditions that accelerate intervertebral disc degeneration: overload versus immobilization.

scientific article
Compression-induced changes in intervertebral disc properties in a rat tail model.

scientific article
Role of biomechanics in intervertebral disc degeneration and regenerative therapies: what needs repairing in the disc and what are promising biomaterials for its repair?

scientific article published on 29 January 2013
Defining the phenotype of young healthy nucleus pulposus cells: recommendations of the Spine Research Interest Group at the 2014 annual ORS meeting

scientific article
Needle puncture injury affects intervertebral disc mechanics and biology in an organ culture model

scientific article published on February 2008
Is the nucleus pulposus a solid or a fluid? Mechanical behaviors of the nucleus pulposus of the human intervertebral disc.

scientific article published on May 1996
Degeneration affects the anisotropic and nonlinear behaviors of human anulus fibrosus in compression

scientific article published on 01 June 1998
In vivo remodeling of intervertebral discs in response to short- and long-term dynamic compression

scientific article published on September 2009
The effects of short-term load duration on anabolic and catabolic gene expression in the rat tail intervertebral disc.

scientific article published on 9 April 2005
Molecular mechanisms of biological aging in intervertebral discs

scientific article
Alterations in the mechanical behavior of the human lumbar nucleus pulposus with degeneration and aging

scientific article published on 01 March 1997
Measurements of proteoglycan and water content distribution in human lumbar intervertebral discs.

scientific article
A role for TNFα in intervertebral disc degeneration: a non-recoverable catabolic shift.

scientific article published on 22 February 2013
Effects of immobilization and dynamic compression on intervertebral disc cell gene expression in vivo

scientific article published in May 2003
Complex loading affects intervertebral disc mechanics and biology

scientific article
Tensile properties of nondegenerate human lumbar anulus fibrosus

scientific article published on 01 February 1996
Notochordal conditioned media from tissue increases proteoglycan accumulation and promotes a healthy nucleus pulposus phenotype in human mesenchymal stem cells.

scientific article published on 31 May 2011
Mechanical homeostasis is altered in uterine leiomyoma

scientific article published on April 2008
Genetic polymorphisms associated with intervertebral disc degeneration.

scientific article published on March 2013
Mechanisms for mechanical damage in the intervertebral disc annulus fibrosus.

scientific article published in August 2004
Dynamic fibroblast cytoskeletal response to subcutaneous tissue stretch ex vivo and in vivo

scientific article published on 20 October 2004
Behavior of mesenchymal stem cells in the chemical microenvironment of the intervertebral disc

scientific journal article
Shear mechanical properties of human lumbar annulus fibrosus

scientific article published in September 1999
In vitro organ culture of the bovine intervertebral disc: effects of vertebral endplate and potential for mechanobiology studies

scientific article
The viscoelastic behavior of the non-degenerate human lumbar nucleus pulposus in shear

scientific article published on 01 October 1997
Pentosan polysulfate: a novel therapy for the mucopolysaccharidoses

scientific article (publication date: 2013)
Confined compression experiments on bovine nucleus pulposus and annulus fibrosus: sensitivity of the experiment in the determination of compressive modulus and hydraulic permeability.

scientific article
Intervertebral disc cell response to dynamic compression is age and frequency dependent.

scientific article published on June 2009
Combined anti-inflammatory and anti-AGE drug treatments have a protective effect on intervertebral discs in mice with diabetes

scientific article
Characterization of an in vitro intervertebral disc organ culture system.

scientific article published on 14 February 2007
Needle puncture injury of the rat intervertebral disc affects torsional and compressive biomechanics differently.

scientific article
Regenerative potential of TGFβ3 + Dex and notochordal cell conditioned media on degenerated human intervertebral disc cells

scientific article published on August 22, 2011
MSC response to pH levels found in degenerating intervertebral discs

scientific journal article
Quantitative MRI as a diagnostic tool of intervertebral disc matrix composition and integrity.

scientific article published on 13 November 2008
Analysis of quantitative magnetic resonance imaging and biomechanical parameters on human discs with different grades of degeneration

scientific article published on April 30, 2013
Measurement of local strains in intervertebral disc anulus fibrosus tissue under dynamic shear: contributions of matrix fiber orientation and elastin content.

scientific article published on 06 August 2009
The effects of needle puncture injury on microscale shear strain in the intervertebral disc annulus fibrosus

scientific article
Frequency-dependent behavior of the intervertebral disc in response to each of six degree of freedom dynamic loading: solid phase and fluid phase contributions.

scientific article published on July 2008
Correlating material properties with tissue composition in enzymatically digested bovine annulus fibrosus and nucleus pulposus tissue.

scientific article published on 06 April 2006
Assessment of compressive modulus, hydraulic permeability and matrix content of trypsin-treated nucleus pulposus using quantitative MRI.

scientific article
Effects of torsion on intervertebral disc gene expression and biomechanics, using a rat tail model.

scientific article published on April 2011
Localized Intervertebral Disc Injury Leads to Organ Level Changes in Structure, Cellularity, and Biosynthesis

scientific article
Intervertebral Disk Degeneration and Repair

scientific article published on March 2017
Outcomes and complications of diabetes mellitus on patients undergoing degenerative lumbar spine surgery

scientific article
Soluble factors from the notochordal-rich intervertebral disc inhibit endothelial cell invasion and vessel formation in the presence and absence of pro-inflammatory cytokines

scientific article
Effects of enzymatic digestion on compressive properties of rat intervertebral discs.

scientific article
Mechanical damage to the intervertebral disc annulus fibrosus subjected to tensile loading

scientific article published in March 2005
Fibroblast cytoskeletal remodeling contributes to connective tissue tension

scientific article published on May 1, 2011
Annular puncture with tumor necrosis factor-alpha injection enhances painful behavior with disc degeneration in vivo.

scientific article
Height and torsional stiffness are most sensitive to annular injury in large animal intervertebral discs.

scientific article

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