List of works - Andrew Singleton

alpha-Synuclein locus triplication causes Parkinson's disease

scientific article

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

scientific article

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

scientific article

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia

scientific article

TREM2 Variants in Alzheimer's Disease

scientific article published on November 14, 2012

Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease

scientific article

Genome-wide association study reveals genetic risk underlying Parkinson's disease

scientific article

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

scientific article (publication date: May 2011)

Systematic identification of trans eQTLs as putative drivers of known disease associations

scientific article (publication date: October 2013)

Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease.

scientific article

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease

scientific article (publication date: September 2014)

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies

scientific article

Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain

scientific article

Genome-wide SNP assay reveals structural genomic variation, extended homozygosity and cell-line induced alterations in normal individuals

scientific article published on 20 November 2006

New loci associated with kidney function and chronic kidney disease

scientific article

Common genetic variants influence human subcortical brain structures

scientific article

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article

Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium

scientific article

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

scientific article published in February 2013

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

scientific article published on 14 March 2012

Genomewide association studies and human disease

scientific article

Genetic variability in the regulation of gene expression in ten regions of the human brain

scientific article

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database

scientific article

Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease

scientific article

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

scientific article

A genome-wide association study identifies protein quantitative trait loci (pQTLs)

scientific article

Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes

scientific article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

scientific article

A common LRRK2 mutation in idiopathic Parkinson's disease

scientific article published on 29 January 2005

Genome-wide genotyping in Parkinson's disease and neurologically normal controls: first stage analysis and public release of data

scientific journal article

Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium

scientific article

Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes

scientific article

Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease

scientific article

A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci

scientific article published on 11 September 2017

DNA methylation-based measures of biological age: meta-analysis predicting time to death

scientific article

Distinct DNA methylation changes highly correlated with chronological age in the human brain

scientific article

Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study

scientific article

Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis

scientific article (publication date: May 2014)

Epigenetic Signatures of Cigarette Smoking

scientific article

Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease

scientific article (publication date: 15 November 2010)

Association of cerebrospinal fluid β-amyloid 1-42, T-tau, P-tau181, and α-synuclein levels with clinical features of drug-naive patients with early Parkinson disease

scientific article

Characterization of PLA2G6 as a locus for dystonia-parkinsonism

scientific article

SNCA variants are associated with increased risk for multiple system atrophy

scientific article

Genotype-imputation accuracy across worldwide human populations

scientific article published on February 2009

Mutations in the gene LRRK2 encoding dardarin (PARK8) cause familial Parkinson's disease: clinical, pathological, olfactory and functional imaging and genetic data

scientific article

Genetics of Parkinson's disease and parkinsonism

scientific article published on October 2006

Meta-analysis of genome-wide association data identifies two loci influencing age at menarche

scientific article

List of works by Andrew Singleton

alpha-Synuclein locus triplication causes Parkinson's disease

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia

TREM2 Variants in Alzheimer's Disease

Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease

Genome-wide association study reveals genetic risk underlying Parkinson's disease

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

Systematic identification of trans eQTLs as putative drivers of known disease associations

Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease.

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies

Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain

Genome-wide SNP assay reveals structural genomic variation, extended homozygosity and cell-line induced alterations in normal individuals

New loci associated with kidney function and chronic kidney disease

Common genetic variants influence human subcortical brain structures

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

Genomewide association studies and human disease

Genetic variability in the regulation of gene expression in ten regions of the human brain

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database

Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

A genome-wide association study identifies protein quantitative trait loci (pQTLs)

Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

A common LRRK2 mutation in idiopathic Parkinson's disease

Genome-wide genotyping in Parkinson's disease and neurologically normal controls: first stage analysis and public release of data

Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium

Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes

Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease

A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci

DNA methylation-based measures of biological age: meta-analysis predicting time to death

Distinct DNA methylation changes highly correlated with chronological age in the human brain

Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study

Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis

Epigenetic Signatures of Cigarette Smoking

Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease

Association of cerebrospinal fluid β-amyloid 1-42, T-tau, P-tau181, and α-synuclein levels with clinical features of drug-naive patients with early Parkinson disease

Characterization of PLA2G6 as a locus for dystonia-parkinsonism

SNCA variants are associated with increased risk for multiple system atrophy

Genotype-imputation accuracy across worldwide human populations

Mutations in the gene LRRK2 encoding dardarin (PARK8) cause familial Parkinson's disease: clinical, pathological, olfactory and functional imaging and genetic data

Genetics of Parkinson's disease and parkinsonism

Meta-analysis of genome-wide association data identifies two loci influencing age at menarche