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List of works by Rajasekharan Somasundaram

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Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

scientific article published in Nature
Intratumoral heterogeneity as a therapy resistance mechanism: role of melanoma subpopulations

scientific article published on January 2012
A stress-induced early innate response causes multidrug tolerance in melanoma

scientific article published on 24 November 2014
Tumor-associated B-cells induce tumor heterogeneity and therapy resistance

scientific article published on 19 September 2017
Chemokines and the microenvironment in neuroectodermal tumor-host interaction

scientific article
Melanoma-derived conditioned media efficiently induce the differentiation of monocytes to macrophages that display a highly invasive gene signature

scientific article published on July 2012
Human leukocyte antigen-A2-restricted CTL responses to mutated BRAF peptides in melanoma patients.

scientific article published on March 2006
Migration of cytotoxic T lymphocytes toward melanoma cells in three-dimensional organotypic culture is dependent on CCL2 and CCR4

scientific article published on 01 February 2006
Melanoma exosomes: messengers of metastasis

scientific article
CXC chemokine ligand 12 (stromal cell-derived factor 1 alpha) and CXCR4-dependent migration of CTLs toward melanoma cells in organotypic culture

scientific article
Erratum: A stress-induced early innate response causes multidrug tolerance in melanoma

article
Peptides mimicking GD2 ganglioside elicit cellular, humoral and tumor-protective immune responses in mice

scientific article
Targeting CD20 in melanoma patients at high risk of disease recurrence.

scientific article
Comparative secretome analysis of epithelial and mesenchymal subpopulations of head and neck squamous cell carcinoma identifies S100A4 as a potential therapeutic target

scientific article published on 13 September 2013
Immunogenicity of recombinant GA733-2E antigen (CO17-1A, EGP, KS1-4, KSA, Ep-CAM) in gastro-intestinal carcinoma patients

scientific article published on 01 April 2001
Heterogeneity in Melanoma

scientific article
Colon carcinoma cells induce CXCL11-dependent migration of CXCR3-expressing cytotoxic T lymphocytes in organotypic culture.

scientific article published on 17 June 2006
CD4(+), HLA class I-restricted, cytolytic T-lymphocyte clone against primary malignant melanoma cells

scientific article published on 01 January 2000
A slow-cycling subpopulation of melanoma cells with highly invasive properties.

scientific article published on 18 September 2017
Isolation of the melanoma-associated antigen p23 using antibody phage display.

scientific article
Cancer vaccines: single-epitope anti-idiotype vaccine versus multiple-epitope antigen vaccine

scientific article published in June 2000
Co-targeting BET and MEK as salvage therapy for MAPK and checkpoint inhibitor-resistant melanoma

scientific article published on 12 April 2018
Cytotoxic T-cell clone against rectal carcinoma induced by stimulation of a patient's peripheral blood mononuclear cells with autologous cultured tumor cells

scientific article published on 01 May 1997
The Multifaceted Roles of B Cells in Solid Tumors: Emerging Treatment Opportunities

scientific article published on 9 March 2017
In vitro migration of cytotoxic T lymphocyte derived from a colon carcinoma patient is dependent on CCL2 and CCR2.

scientific article
Preferential involvement of CX chemokine receptor 4 and CX chemokine ligand 12 in T-cell migration toward melanoma cells.

scientific article published on 4 October 2006
Nivolumab in combination with ipilimumab for the treatment of melanoma

scientific article published on October 2015
Induction of Telomere Dysfunction Prolongs Disease Control of Therapy-Resistant Melanoma

scientific article published on 21 March 2018
SECTM1 produced by tumor cells attracts human monocytes via CD7-mediated activation of the PI3K pathway.

scientific article published on 24 October 2013
Anti-idiotype cancer vaccines: pre-clinical and clinical studies

scientific article published on 01 November 1991
Shared MHC class II-dependent melanoma ribosomal protein L8 identified by phage display

article
Immunomodulatory activity of monoclonal anti-idiotypic antibody to anti-colorectal carcinoma antibody CO17-1A in animals and patients

scientific article published on 01 May 1994
Induction of cellular immunity by anti-idiotypic antibodies mimicking GD2 ganglioside

scientific article published on 11 February 2003
Limitations of the severe combined immunodeficiency (SCID) mouse model for study of human B-cell responses

scientific article published on 01 April 1995
Monoclonal anti-idiotypic antibody functionally mimics the human gastrointestinal carcinoma epitope GA733

scientific article published on 01 February 1996
Induction of antigen-specific T and B cell immunity in colon carcinoma patients by anti-idiotypic antibody

scientific article published on 01 September 1995
Type I-polarized BRAF-pulsed dendritic cells induce antigen-specific CD8+ T cells that impact BRAF-mutant murine melanoma

scientific article published on 8 October 2015
Serum antibodies to EpCAM in healthy donors but not ulcerative colitis patients

scientific article published on 21 July 2005
Monoclonal anti-idiotypic antibody mimicking the gastrointestinal carcinoma-associated epitope CO17-1A elicits antigen-specific humoral and cellular immune responses in colorectal cancer patients

scientific article published on 01 April 2003
Nucleophosmin is recognized by a cytotoxic T cell line derived from a rectal carcinoma patient.

scientific article
Anti-idiotypic antibody (ab2) vaccines: coupling of Ab2 BR3E4 to KLH increases humoral and/or cellular immune responses in animals and colorectal cancer patients

scientific article published on 01 October 2001
Human colorectal cancer (CRC) antigen CO17-1A/GA733 encoded by adenovirus inhibits growth of established CRC cells in mice.

scientific article published in July 1997
Will engineered T cells expressing CD20 scFv eradicate Melanoma?

scientific article published on April 2011
Immunotargeting of tumor subpopulations in melanoma patients: A paradigm shift in therapy approaches

scientific article published on November 2012
Animal models of human-derived cancer vaccines.

scientific article published on August 1995
Detection of HLA class II-dependent T helper antigen using antigen phage display.

scientific article
Interleukin-2 mediated regulation of mitogen-activated T cell reactivity from different lymphoid sources in patients with squamous cell carcinoma of the oral cavity

scientific article published on 01 July 1989
In vitro generation of effector cells cytotoxic to autologous targets from chronic myeloid leukemia patients in remission

scientific article published on 01 January 1988
Propagation of cytotoxic effectors from chronic myeloid leukemia patients and cloning of cytotoxic T cells

scientific article published on 01 January 1988
Indomethacin to the rescue of TRAIL-resistant melanomas

scientific article published on 01 May 2014

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