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List of works by Isabel Fabregat

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Snail blocks the cell cycle and confers resistance to cell death

scientific journal article
Reactive oxygen species (ROS) mediates the mitochondrial-dependent apoptosis induced by transforming growth factor (beta) in fetal hepatocytes.

scientific article published in March 2001
Dysregulation of apoptosis in hepatocellular carcinoma cells

scientific article published in February 2009
TGF-β signalling and liver disease.

scientific article
Upregulation of the NADPH oxidase NOX4 by TGF-beta in hepatocytes is required for its pro-apoptotic activity

scientific journal article
Apoptosis Induced by Transforming Growth Factor- in Fetal Hepatocyte Primary Cultures

scientific article published in Journal of Biological Chemistry
The epithelial mesenchymal transition confers resistance to the apoptotic effects of transforming growth factor Beta in fetal rat hepatocytes

scientific article published on 01 November 2002
Survival and apoptosis: a dysregulated balance in liver cancer

scientific article published on March 2007
Involvement of EGF receptor and c-Src in the survival signals induced by TGF-beta1 in hepatocytes

scientific journal article
NADPH oxidase NOX4 mediates stellate cell activation and hepatocyte cell death during liver fibrosis development.

scientific article
Molecular mechanisms of insulin resistance in IRS-2-deficient hepatocytes

scientific article published in September 2003
Source of early reactive oxygen species in the apoptosis induced by transforming growth factor-beta in fetal rat hepatocytes

scientific article
European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).

scientific article published on 18 May 2017
New Insights into the Crossroads between EMT and Stemness in the Context of Cancer

scientific article
Snail1 suppresses TGF-beta-induced apoptosis and is sufficient to trigger EMT in hepatocytes

scientific article published on October 2010
Overactivation of the TGF-β pathway confers a mesenchymal-like phenotype and CXCR4-dependent migratory properties to liver tumor cells.

scientific article published on 11 October 2013
Efficient execution of cell death in non-glycolytic cells requires the generation of ROS controlled by the activity of mitochondrial H+-ATP synthase

scientific article published on 16 December 2005
TGF-beta signaling in cancer treatment

scientific article published on January 2014
Hematopoietic mobilization in mice increases the presence of bone marrow-derived hepatocytes via in vivo cell fusion

scientific article published in January 2006
Overactivation of the MEK/ERK pathway in liver tumor cells confers resistance to TGF-{beta}-induced cell death through impairing up-regulation of the NADPH oxidase NOX4.

scientific article published on 22 September 2009
Impaired mitochondrial oxidative phosphorylation in the peroxisomal disease X-linked adrenoleukodystrophy

scientific article published on 20 April 2013
The transforming growth factor-beta (TGF-β) mediates acquisition of a mesenchymal stem cell-like phenotype in human liver cells

scientific article
A mesenchymal-like phenotype and expression of CD44 predict lack of apoptotic response to sorafenib in liver tumor cells

scientific article published on 04 August 2014
c-Myc regulates cell size and ploidy but is not essential for postnatal proliferation in liver

scientific article
Vascular smooth muscle cell phenotypic changes in patients with Marfan syndrome.

scientific article
Glucose deprivation induces an atypical form of apoptosis mediated by caspase-8 in Bax-, Bak-deficient cells.

scientific article
The inhibition of the epidermal growth factor (EGF) pathway enhances TGF-beta-induced apoptosis in rat hepatoma cells through inducing oxidative stress coincident with a change in the expression pattern of the NADPH oxidases (NOX) isoforms

scientific journal article
Role of NADPH oxidases in the redox biology of liver fibrosis

scientific article
Activation of NADPH oxidase by transforming growth factor-beta in hepatocytes mediates up-regulation of epidermal growth factor receptor ligands through a nuclear factor-kappaB-dependent mechanism

scientific article published on July 2007
EGF blocks NADPH oxidase activation by TGF-beta in fetal rat hepatocytes, impairing oxidative stress, and cell death.

scientific article
NADPH oxidase NOX1 controls autocrine growth of liver tumor cells through up-regulation of the epidermal growth factor receptor pathway

scientific article
Differential Inhibition of the TGF-β Signaling Pathway in HCC Cells Using the Small Molecule Inhibitor LY2157299 and the D10 Monoclonal Antibody against TGF-β Receptor Type II.

scientific article
Differential intracellular signalling induced by TGF-beta in rat adult hepatocytes and hepatoma cells: implications in liver carcinogenesis.

scientific article published on 16 September 2006
The NADPH oxidase NOX4 inhibits hepatocyte proliferation and liver cancer progression

scientific article published on 6 February 2014
Sorafenib sensitizes hepatocellular carcinoma cells to physiological apoptotic stimuli.

scientific article
Role of CXCR4/SDF-1 alpha in the migratory phenotype of hepatoma cells that have undergone epithelial-mesenchymal transition in response to the transforming growth factor-beta

scientific article
Transforming growth factor-beta activates both pro-apoptotic and survival signals in fetal rat hepatocytes

scientific article
The NADPH oxidase inhibitor VAS2870 impairs cell growth and enhances TGF-β-induced apoptosis of liver tumor cells

scientific article published on January 26, 2011
Autocrine production of TGF-β confers resistance to apoptosis after an epithelial–mesenchymal transition process in hepatocytes: Role of EGF receptor ligands

scientific article published on 07 June 2006
Epidermal Growth Factor Impairs the Cytochrome C/Caspase-3 Apoptotic Pathway Induced by Transforming Growth Factorβ in Rat Fetal Hepatocytes Via a Phosphoinositide 3-Kinase–Dependent Pathway

scientific article published on 01 September 2000
The rationale for targeting TGF-β in chronic liver diseases.

scientific article published on 29 January 2016
Transforming growth factor ? modulates growth and differentiation of fetal hepatocytes in primary culture

scientific article published on 01 November 1995
IRS-2 mediates the antiapoptotic effect of insulin in neonatal hepatocytes

scientific article published in December 2004
Differential proliferative response of cultured fetal and regenerating hepatocytes to growth factors and hormones

scientific article published on 01 October 1992
Epidermal growth factor, but not hepatocyte growth factor, suppresses the apoptosis induced by transforming growth factor-beta in fetal hepatocytes in primary culture

article
TGF-beta dependent regulation of oxygen radicals during transdifferentiation of activated hepatic stellate cells to myofibroblastoid cells

scientific article published on 20 February 2007
Transforming growth factor-β-induced plasticity causes a migratory stemness phenotype in hepatocellular carcinoma.

scientific article published on February 2017
BMP9 is a proliferative and survival factor for human hepatocellular carcinoma cells

scientific article
Dissecting the effect of targeting the epidermal growth factor receptor on TGF-β-induced-apoptosis in human hepatocellular carcinoma cells.

scientific article published on 13 December 2010
Transforming Growth Factor-β-Induced Cell Plasticity in Liver Fibrosis and Hepatocarcinogenesis

scientific article published on 10 September 2018

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