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List of works by Nico P. Dantuma

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VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD

scientific journal article
Heterochromatin protein 1 is recruited to various types of DNA damage.

scientific article published on May 2009
The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks

scientific article
A dynamic ubiquitin equilibrium couples proteasomal activity to chromatin remodeling

scientific article
Disease-associated prion protein oligomers inhibit the 26S proteasome

scientific article published on April 2007
Aggregate formation inhibits proteasomal degradation of polyglutamine proteins.

scientific article published in October 2002
A transgenic mouse model of the ubiquitin/proteasome system

scientific article published on 20 July 2003
Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response

scientific article
Endoplasmic reticulum stress compromises the ubiquitin-proteasome system

scientific article published on 15 August 2005
Neuronal dysfunction in a polyglutamine disease model occurs in the absence of ubiquitin-proteasome system impairment and inversely correlates with the degree of nuclear inclusion formation

scientific article published on 20 January 2005
The ubiquitin-proteasome system in neurodegenerative diseases: precipitating factor, yet part of the solution

scientific article
A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo

scientific article
A conserved unfoldase activity for the p97 AAA-ATPase in proteasomal degradation

scientific article published on 24 September 2009
Spatiotemporal regulation of posttranslational modifications in the DNA damage response

scientific article published on January 4, 2016
The ubiquitin receptor Rad23: at the crossroads of nucleotide excision repair and proteasomal degradation

scientific article published on 14 February 2009
Functional alterations of the ubiquitin-proteasome system in motor neurons of a mouse model of familial amyotrophic lateral sclerosis

scientific article published on 29 September 2008
A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure

scientific article
DDB2 promotes chromatin decondensation at UV-induced DNA damage

scientific article published on 9 April 2012
The UBA2 domain functions as an intrinsic stabilization signal that protects Rad23 from proteasomal degradation

scientific article
Acute polyglutamine expression in inducible mouse model unravels ubiquitin/proteasome system impairment and permanent recovery attributable to aggregate formation.

scientific article published in March 2010
Growing sphere of influence: Cdc48/p97 orchestrates ubiquitin-dependent extraction from chromatin

scientific article published on July 19, 2012
Dose-dependent inhibition of proteasome activity by a mutant ubiquitin associated with neurodegenerative disease

scientific article published on 3 April 2007
Alzheimer's disease-associated ubiquilin-1 regulates presenilin-1 accumulation and aggresome formation

scientific article
Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment

scientific article published on 30 July 2009
Fluorescent probes for proteolysis: tools for drug discovery

scientific article published on January 2004
Selective accumulation of aggregation-prone proteasome substrates in response to proteotoxic stress

scientific article
Minimal length requirement for proteasomal degradation of ubiquitin-dependent substrates

scientific article published on 16 September 2008
Recognition of DNA damage by XPC coincides with disruption of the XPC-RAD23 complex

scientific article published in March 2012
Stressing the ubiquitin-proteasome system

scientific article published on 25 July 2009
Ubiquitin crosstalk connecting cellular processes

scientific article
Functional p53 chimeras containing the Epstein-Barr virus Gly-Ala repeat are protected from Mdm2- and HPV-E6-induced proteolysis

scientific article
Should I stay or should I go: VCP/p97-mediated chromatin extraction in the DNA damage response

scientific article (publication date: 15 November 2014)
C-terminal UBA domains protect ubiquitin receptors by preventing initiation of protein degradation

scientific article published on 8 February 2011
The chromosomal association of the Smc5/6 complex depends on cohesion and predicts the level of sister chromatid entanglement.

scientific article
Inhibition of ubiquitin/proteasome-dependent proteolysis in Saccharomyces cerevisiae by a Gly-Ala repeat

scientific article
Monitoring the ubiquitin/proteasome system in conformational diseases

scientific article published on October 2003
The Epstein-Barr virus nuclear antigen-1 reprograms transcription by mimicry of high mobility group A proteins

scientific article published on 28 January 2013
Monitoring of ubiquitin-dependent proteolysis with green fluorescent protein substrates

scientific article published in January 2005
Mutant ubiquitin (UBB+1) associated with neurodegenerative disorders is hydrolyzed by ubiquitin C-terminal hydrolase L3 (UCH-L3)

scientific article
A small-molecule Nrf1 and Nrf2 activator mitigates polyglutamine toxicity in spinal and bulbar muscular atrophy

scientific article
Illuminating the ubiquitin/proteasome system

scientific article published on 10 February 2010
Electron microscopic visualization of receptor-mediated endocytosis of Dil-labeled lipoproteins by diaminobenzidine photoconversion

scientific article
Proteasome inhibition up-regulates p53 and apoptosis-inducing factor in chondrocytes causing severe growth retardation in mice

scientific article published in October 2007
Expression of progerin in aging mouse brains reveals structural nuclear abnormalities without detectible significant alterations in gene expression, hippocampal stem cells or behavior

scientific article
Pathways accessory to proteasomal proteolysis are less efficient in major histocompatibility complex class I antigen production

scientific article
The ubiquitin/proteasome system in Epstein-Barr virus latency and associated malignancies.

scientific article
Cdc48-independent proteasomal degradation coincides with a reduced need for ubiquitylation

scientific article published on 5 January 2015
Independent mechanisms recruit the cohesin loader protein NIPBL to sites of DNA damage

scientific article
Ataxin-3 consolidates the MDC1-dependent DNA double-strand break response by counteracting the SUMO-targeted ubiquitin ligase RNF4.

scientific article published on 8 March 2017
Mutant p62/SQSTM1 UBA domains linked to Paget's disease of bone differ in their abilities to function as stabilization signals

scientific article published on 15 March 2010

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