List of works - Stephen J Jenkins

Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation

scientific article

Tissue-resident macrophages

scientific article published on September 18, 2013

IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1

scientific article published on 07 October 2013

Distinct bone marrow-derived and tissue-resident macrophage lineages proliferate at key stages during inflammation

scientific article published on January 2013

Alternatively activated macrophages derived from monocytes and tissue macrophages are phenotypically and functionally distinct.

scientific article

Alternatively activated dendritic cells regulate CD4+ T-cell polarization in vitro and in vivo

scientific article

CSF1 Restores Innate Immunity After Liver Injury in Mice and Serum Levels Indicate Outcomes of Patients With Acute Liver Failure

scientific article

Induction of IL-4Rα-dependent microRNAs identifies PI3K/Akt signaling as essential for IL-4-driven murine macrophage proliferation in vivo.

scientific article

Homeostasis in the mononuclear phagocyte system

scientific article published on July 18, 2014

Similarity and diversity in macrophage activation by nematodes, trematodes, and cestodes.

scientific article

Innate and adaptive type 2 immune cell responses in genetically controlled resistance to intestinal helminth infection

scientific article

Dendritic cells activated with products released by schistosome larvae drive Th2-type immune responses, which can be inhibited by manipulation of CD40 costimulation

scientific article

Schistosome larvae stimulate macrophage cytokine production through TLR4-dependent and -independent pathways.

scientific article

The Mannose Receptor (CD206) is an important pattern recognition receptor (PRR) in the detection of the infective stage of the helminth Schistosoma mansoni and modulates IFNγ production

scientific article

Dendritic cell activation and function in response to Schistosoma mansoni.

scientific article

A pivotal role for CD40-mediated IL-6 production by dendritic cells during IL-17 induction in vivo

scientific article

The adult murine heart has a sparse, phagocytically active macrophage population that expands through monocyte recruitment and adopts an 'M2' phenotype in response to Th2 immunologic challenge.

scientific article published on 7 February 2015

Unconventional maturation of dendritic cells induced by particles from the laminated layer of larval Echinococcus granulosus

scientific article

Distinct sources and targets of IL-10 during dendritic cell-driven Th1 and Th2 responses in vivo.

scientific article published in September 2006

Macrophage origin limits functional plasticity in helminth-bacterial co-infection

scientific article

Csf1r-mApple Transgene Expression and Ligand Binding In Vivo Reveal Dynamics of CSF1R Expression within the Mononuclear Phagocyte System.

scientific article published on 12 February 2018

Full development of Th2 immunity requires both innate and adaptive sources of CD154.

scientific article published in June 2008

Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations

scientific article published on 19 July 2019

Interleukin-4 activated macrophages mediate immunity to filarial helminth infection by sustaining CCR3-dependent eosinophilia.

scientific article

Rate of replenishment and microenvironment contribute to the sexually dimorphic phenotype and function of peritoneal macrophages

scientific article published on 01 June 2020

Local proliferation of monocytes

scientific article published on 28 February 2020

Recruited macrophages that colonize the post-inflammatory peritoneal niche convert into functionally divergent resident cells

scientific article published on 19 March 2021

Role of Tim4 in the regulation of ABCA1⁺ adipose tissue macrophages and post-prandial cholesterol levels

scientific article published on 21 July 2021

Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation

scientific article published on 27 May 2022

Cell origin and niche availability dictate the capacity of peritoneal macrophages to colonize the cavity and omentum

scientific article published in 2022

List of works by Stephen J Jenkins

Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation

Tissue-resident macrophages

IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1

Distinct bone marrow-derived and tissue-resident macrophage lineages proliferate at key stages during inflammation

Alternatively activated macrophages derived from monocytes and tissue macrophages are phenotypically and functionally distinct.

Alternatively activated dendritic cells regulate CD4+ T-cell polarization in vitro and in vivo

CSF1 Restores Innate Immunity After Liver Injury in Mice and Serum Levels Indicate Outcomes of Patients With Acute Liver Failure

Induction of IL-4Rα-dependent microRNAs identifies PI3K/Akt signaling as essential for IL-4-driven murine macrophage proliferation in vivo.

Homeostasis in the mononuclear phagocyte system

Similarity and diversity in macrophage activation by nematodes, trematodes, and cestodes.

Innate and adaptive type 2 immune cell responses in genetically controlled resistance to intestinal helminth infection

Dendritic cells activated with products released by schistosome larvae drive Th2-type immune responses, which can be inhibited by manipulation of CD40 costimulation

Schistosome larvae stimulate macrophage cytokine production through TLR4-dependent and -independent pathways.

The Mannose Receptor (CD206) is an important pattern recognition receptor (PRR) in the detection of the infective stage of the helminth Schistosoma mansoni and modulates IFNγ production

Dendritic cell activation and function in response to Schistosoma mansoni.

A pivotal role for CD40-mediated IL-6 production by dendritic cells during IL-17 induction in vivo

The adult murine heart has a sparse, phagocytically active macrophage population that expands through monocyte recruitment and adopts an 'M2' phenotype in response to Th2 immunologic challenge.

Unconventional maturation of dendritic cells induced by particles from the laminated layer of larval Echinococcus granulosus

Distinct sources and targets of IL-10 during dendritic cell-driven Th1 and Th2 responses in vivo.

Macrophage origin limits functional plasticity in helminth-bacterial co-infection

Csf1r-mApple Transgene Expression and Ligand Binding In Vivo Reveal Dynamics of CSF1R Expression within the Mononuclear Phagocyte System.

Full development of Th2 immunity requires both innate and adaptive sources of CD154.

Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations

Interleukin-4 activated macrophages mediate immunity to filarial helminth infection by sustaining CCR3-dependent eosinophilia.

Rate of replenishment and microenvironment contribute to the sexually dimorphic phenotype and function of peritoneal macrophages

Local proliferation of monocytes

Recruited macrophages that colonize the post-inflammatory peritoneal niche convert into functionally divergent resident cells

Role of Tim4 in the regulation of ABCA1⁺ adipose tissue macrophages and post-prandial cholesterol levels

Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation

Cell origin and niche availability dictate the capacity of peritoneal macrophages to colonize the cavity and omentum