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List of works by Katie Lunnon

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Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood

scientific article
A data-driven approach to preprocessing Illumina 450K methylation array data

scientific article
Central and systemic endotoxin challenges exacerbate the local inflammatory response and increase neuronal death during chronic neurodegeneration.

scientific article
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci

scientific article
Systemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative disease

scientific article published on 18 September 2008
Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease

scientific article
Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease

scientific article
Interindividual methylomic variation across blood, cortex, and cerebellum: implications for epigenetic studies of neurological and neuropsychiatric phenotypes

scientific article published on 12 October 2015
Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway

scientific article
Plasma proteins predict conversion to dementia from prodromal disease

scientific article
Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease.

scientific article published on 30 November 2010
Systemic Inflammation Modulates Fc Receptor Expression on Microglia during Chronic Neurodegeneration

scientific article published on 13 May 2011
Mitochondrial dysfunction and immune activation are detectable in early Alzheimer's disease blood

scientific article published on January 2012
A novel multi-tissue RNA diagnostic of healthy ageing relates to cognitive health status

scientific article
Cross-region reduction in 5-hydroxymethylcytosine in Alzheimer's disease brain.

scientific article
Identification of cis-regulatory variation influencing protein abundance levels in human plasma.

scientific article published on 16 May 2012
Variation in 5-hydroxymethylcytosine across human cortex and cerebellum.

scientific article published on 16 February 2016
Inflammatory proteins in plasma are associated with severity of Alzheimer's disease

scientific article
Plasma based markers of [11C] PiB-PET brain amyloid burden

scientific article
A blood gene expression marker of early Alzheimer's disease

scientific article published on January 2013
Epigenetic studies in Alzheimer's disease: current findings, caveats, and considerations for future studies

scientific article published on 13 September 2013
Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum

scientific article
Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseases

scientific article published on 2 November 2015
Genetic architecture of epigenetic and neuronal ageing rates in human brain regions

scientific article
Increased DNA methylation near TREM2 is consistently seen in the superior temporal gyrus in Alzheimer's disease brain

scientific article
Mitochondrial genes are altered in blood early in Alzheimer's disease

scientific article
Epigenetic regulation of adult neural stem cells: implications for Alzheimer's disease

scientific article
Longitudinal analyses of the DNA methylome in deployed military servicemen identify susceptibility loci for post-traumatic stress disorder

scientific article
Alzheimer's disease-associated (hydroxy)methylomic changes in the brain and blood

scientific article published on 27 November 2019
The Mitochondrial Epigenome: a Role in Alzheimer’s Disease?

scientific article published on January 1, 2014
ABCA7 p.G215S as potential protective factor for Alzheimer's disease

scientific article published on 20 April 2016
Epigenetics and DNA methylomic profiling in Alzheimer's disease and other neurodegenerative diseases.

scientific article published on 14 August 2017
Exome sequencing identifies 2 novel presenilin 1 mutations (p.L166V and p.S230R) in British early-onset Alzheimer's disease

scientific article
Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology

article
ANK1 is up-regulated in laser captured microglia in Alzheimer's brain; the importance of addressing cellular heterogeneity.

scientific article
Alzheimer's disease susceptibility variants in the MS4A6A gene are associated with altered levels of MS4A6A expression in blood

scientific article published on 21 September 2013
Tissue-specific patterns of allelically-skewed DNA methylation

scientific article published on 19 January 2016
A histone acetylome-wide association study of Alzheimer's disease identifies disease-associated H3K27ac differences in the entorhinal cortex

scientific article published on 22 October 2018
Epigenetic regulation of mitochondrial function in neurodegenerative disease: New insights from advances in genomic technologies

scientific article published on 10 February 2016
A Pathway Based Classification Method for Analyzing Gene Expression for Alzheimer's Disease Diagnosis

scientific article published on 15 October 2015
Influence of Coding Variability in APP-Aβ Metabolism Genes in Sporadic Alzheimer's Disease

scientific article
Alpha-synuclein deficiency in the C57BL/6JOlaHsd strain does not modify disease progression in the ME7-model of prion disease

scientific article published on 30 October 2009
Blood methylomic signatures of presymptomatic dementia in elderly subjects with type 2 diabetes mellitus

scientific article published on 24 December 2014
A comparison of mitochondrial DNA isolation methods in frozen post-mortem human brain tissue--applications for studies of mitochondrial genetics in brain disorders

scientific article
Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer's disease

scientific article published on 21 March 2019
Regional differences in mitochondrial DNA methylation in human post-mortem brain tissue

scientific article
Epigenetic dysregulation of brainstem nuclei in the pathogenesis of Alzheimer's disease: looking in the correct place at the right time?

scientific article published on 14 September 2016
Peripheral DNA methylation, cognitive decline and brain aging: pilot findings from the Whitehall II imaging study

scientific article published on 25 April 2018
Using induced pluripotent stem cells to explore genetic and epigenetic variation associated with Alzheimer's disease.

scientific article published on 3 October 2017
DNA Modifications and Alzheimer's Disease.

scientific article published in January 2017

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