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List of works by Silvia Marsoni

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Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer

scientific article
A molecularly annotated platform of patient-derived xenografts ("xenopatients") identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer

scientific article
Integrating liquid biopsies into the management of cancer

scientific article published on 2 March 2017
Erlotinib versus docetaxel as second-line treatment of patients with advanced non-small-cell lung cancer and wild-type EGFR tumours (TAILOR): a randomised controlled trial

scientific article published on 22 July 2013
Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients.

scientific article
Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-label, phase 2 trial

scientific article
DNA mismatch repair status and colon cancer recurrence and survival in clinical trials of 5-fluorouracil-based adjuvant therapy.

scientific article
The genomic landscape of response to EGFR blockade in colorectal cancer.

scientific article published on 30 September 2015
Inhibition of MEK and PI3K/mTOR suppresses tumor growth but does not cause tumor regression in patient-derived xenografts of RAS-mutant colorectal carcinomas

scientific article
Erratum: Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients

scientific article published on 01 July 2015
Trabectedin for women with ovarian carcinoma after treatment with platinum and taxanes fails.

scientific article
Assessment of a HER2 scoring system for colorectal cancer: results from a validation study

scientific article published on 09 October 2015
Locoregionally advanced carcinoma of the oropharynx: conventional radiotherapy vs. accelerated hyperfractionated radiotherapy vs. concomitant radiotherapy and chemotherapy--a multicenter randomized trial

scientific article
A first in human phase I study of the proteasome inhibitor CEP-18770 in patients with advanced solid tumours and multiple myeloma

scientific article published on 08 October 2012
KRAS mutations affect prognosis of non-small-cell lung cancer patients treated with first-line platinum containing chemotherapy

scientific article published on 15 September 2015
Pharmacodynamic trial of nimotuzumab in unresectable squamous cell carcinoma of the head and neck: a SENDO Foundation study.

scientific article published on 6 April 2010
Phase I clinical and pharmacokinetic study of trabectedin and cisplatin in solid tumours

scientific article published on 4 May 2009
Adjuvant portal-vein infusion of fluorouracil and heparin in colorectal cancer: a randomised trial

scientific article published in The Lancet
Incidence, risk factors and clinical implications of venous thromboembolism in cancer patients treated within the context of phase I studies: the 'SENDO experience'.

scientific article published on 2 November 2011
Patient selection for oncology phase I trials: a multi-institutional study of prognostic factors

scientific article published on 21 February 2012
Phase IB study of the mTOR inhibitor ridaforolimus with capecitabine.

scientific article published on 20 September 2010
Gene expression profiling and prediction of response to hormonal neoadjuvant treatment with anastrozole in surgically resectable breast cancer

scientific article published on 29 April 2010
Clinical and pharmacological phase I study with accelerated titration design of a daily times five schedule of BBR3464, a novel cationic triplatinum complex

scientific article published on 01 August 2000
An open-label phase 2 study of twice-weekly bortezomib and intermittent pegylated liposomal doxorubicin in patients with ovarian cancer failing platinum-containing regimens

scientific article
Treating childhood acute lymphoblastic leukaemia (ALL): Summary of ten years' experience in Italy

article
Value of KRAS as prognostic or predictive marker in NSCLC: results from the TAILOR trial.

scientific article
Early-onset colorectal cancer in young individuals

scientific article published on 22 December 2018
A phase II study of the histone deacetylase inhibitor panobinostat (LBH589) in pretreated patients with small-cell lung cancer

scientific article
Phase I clinical and pharmacological evaluation of the multi-tyrosine kinase inhibitor SU006668 by chronic oral dosing

scientific article
Dual MET/EGFR therapy leads to complete response and resistance prevention in a MET-amplified gastroesophageal xenopatient cohort

scientific article published on 15 August 2016
Outcome of patients with sarcoma and other mesenchymal tumours participating in phase I trials: a subset analysis of a European Phase I database

scientific article published on 7 March 2014
Concerted escalation of dose and dosing duration in a phase I study of the oral camptothecin gimatecan (ST1481) in patients with advanced solid tumors

scientific article
Tiazofurin: a new antitumor agent.

scientific article published on January 1984
Prediction of early death among patients enrolled in phase I trials: development and validation of a new model based on platelet count and albumin

scientific article published on August 21, 2012
Testing epidermal growth factor receptor mutations in patients with non-small-cell lung cancer to choose chemotherapy: the other side of the coin.

scientific article
Phase I clinical study of the novel epothilone B analogue BMS-310705 given on a weekly schedule

scientific article published on 01 September 2007
Dose-Response Relationship in Phase I Clinical Trials: A European Drug Development Network (EDDN) Collaboration Study

article
Fluorouracil and folinic acid in colon cancer. IMPACT Investigators

Clinical pharmacokinetics of the new oral camptothecin gimatecan: the inter-patient variability is related to alpha1-acid glycoprotein plasma levels.

scientific article published on 16 December 2009
Phase IB and pharmacological study of the novel taxane BMS-184476 in combination with doxorubicin.

scientific article published in March 2004
Actual developments in European regulatory and health technology assessment of new cancer drugs: what does this mean for oncology in Europe?

scientific article published on 10 December 2013
Venous thromboembolism is a relevant and underestimated adverse event in cancer patients treated in phase I studies.

scientific article
Randomized comparison of hexamethylmelamine, adriamycin, cyclophosphamide (hac) vs. cisplatin, adriamycin, cyclophosphamide (pac) in advanced ovarian cancer: long-term results

scientific article published on 01 March 1991
Early ovarian cancer and the icon trials

scientific article published in January 1992
Spiromustine: a new agent entering clinical trials

scientific article published on January 1983
New Omics Information for Clinical Trial Utility in the Primary Setting

scientific article published on 01 January 2011
A proposal for a new approach to intergroup cancer trials

Gut vascular barrier impairment leads to intestinal bacteria dissemination and colorectal cancer metastasis to liver

Fluorouracil and folinic acid in colon cancer

scientific article published in The Lancet
A phase I study of the oral platinum agent satraplatin in sequential combination with capecitabine in the treatment of patients with advanced solid malignancies

scientific article published on 27 December 2010

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