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List of works by Massimo Zucchetti

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Role of Macrophage Targeting in the Antitumor Activity of Trabectedin

scientific article published on 01 February 2013
Role of alpha1 acid glycoprotein in the in vivo resistance of human BCR-ABL(+) leukemic cells to the abl inhibitor STI571

scientific article published on 01 October 2000
Phase I/IIa study evaluating the safety, efficacy, pharmacokinetics, and pharmacodynamics of lucitanib in advanced solid tumors

scientific article (publication date: November 2014)
Distribution of paclitaxel within the nervous system of the rat after repeated intravenous administration

scientific article published on 01 June 2000
Alpha1 acid glycoprotein binds to imatinib (STI571) and substantially alters its pharmacokinetics in chronic myeloid leukemia patients

scientific article
Blockade of the IL-1R1/TLR4 pathway mediates disease-modification therapeutic effects in a model of acquired epilepsy.

scientific article published on 9 December 2016
Pharmacokinetics of concomitant cisplatin and paclitaxel administered by hyperthermic intraperitoneal chemotherapy to patients with peritoneal carcinomatosis from epithelial ovarian cancer

scientific article
L-asparagine depletion and L-asparaginase activity in children with acute lymphoblastic leukemia receiving i.m. or i.v. Erwinia C. or E. coli L-asparaginase as first exposure

scientific article published on 01 February 2000
Effective combination of ET-743 and doxorubicin in sarcoma: preclinical studies

scientific article published on 29 May 2003
A first in human phase I study of the proteasome inhibitor CEP-18770 in patients with advanced solid tumours and multiple myeloma

scientific article published on 08 October 2012
Tumor delivery of chemotherapy combined with inhibitors of angiogenesis and vascular targeting agents

scientific article published on October 2013
Phase I clinical and pharmacokinetic study of trabectedin and doxorubicin in advanced soft tissue sarcoma and breast cancer.

scientific article
Bevacizumab-Induced Inhibition of Angiogenesis Promotes a More Homogeneous Intratumoral Distribution of Paclitaxel, Improving the Antitumor Response.

scientific article published on 22 October 2015
Pharmacokinetics of etoposide in patients with abnormal renal and hepatic function

scientific article published on 01 May 1986
Pharmacokinetics of anticancer agents in patients with impaired liver function

scientific article published on 01 January 1998
Determination of paclitaxel distribution in solid tumors by nano-particle assisted laser desorption ionization mass spectrometry imaging

scientific article (publication date: 2013)
Phase I clinical and pharmacokinetic study of trabectedin and cisplatin in solid tumours

scientific article published on 4 May 2009
Phase I clinical and pharmacokinetic study of the oral platinum analogue JM216 given daily for 14 days

scientific article
Intratumor heterogeneity and its impact on drug distribution and sensitivity

scientific article published on 14 May 2014
Distribution of daunorubicin and daunorubicinol in human glioma tumors after administration of liposomal daunorubicin

scientific article
The tyrosine kinase inhibitor E-3810 combined with paclitaxel inhibits the growth of advanced-stage triple-negative breast cancer xenografts

scientific article
Phase I and clinical pharmacological evaluation of aphidicolin glycinate

scientific article published on 01 August 1991
Chemical characterization of Iraqi propolis samples and assessing their antioxidant potentials

article
Clinical and pharmacological phase I study with accelerated titration design of a daily times five schedule of BBR3464, a novel cationic triplatinum complex

scientific article published on 01 August 2000
Sequence dependent antitumour efficacy of the vascular disrupting agent ZD6126 in combination with paclitaxel.

scientific article published on 11 September 2007
Complete protection by high-dose dexamethasone against the hepatotoxicity of the novel antitumor drug yondelis (ET-743) in the rat

scientific article published on September 15, 2003
Heterogeneity of paclitaxel distribution in different tumor models assessed by MALDI mass spectrometry imaging

scientific article published on 21 December 2016
Metabolic approach to the enhancement of antitumor effect of chemotherapy: a key role of acetyl-L-carnitine

scientific article published on 18 June 2010
Cyclosporin A markedly changes the distribution of doxorubicin in mice and rats.

scientific article
A limited sampling model for the pharmacokinetics of etoposide given orally

scientific article published in January 1993
A pharmacological study on pegylated asparaginase used in front-line treatment of children with acute lymphoblastic leukemia

scientific article published in January 2006
3D Mass Spectrometry Imaging Reveals a Very Heterogeneous Drug Distribution in Tumors

scientific article
Phase I clinical and pharmacokinetic study of oral etoposide phosphate

scientific article published on 01 January 1995
Concentrations of VP16 and VM26 in human brain tumors

scientific article published on 01 January 1991
Differences between in vivo and in vitro sensitivity to imatinib of Bcr/Abl+ cells obtained from leukemic patients.

scientific article published in May 2002
High-performance liquid chromatography tandem mass spectrometry procedure with automated solid phase extraction sample preparation for the quantitative determination of paclitaxel (Taxol) in human plasma

scientific article published on 01 January 1998
Pharmacokinetics and antineoplastic activity of galectin-1-targeting OTX008 in combination with sunitinib.

scientific article published on 24 August 2013
Pharmacokinetics of 4-demethoxydaunorubicin in cancer patients

scientific article published on 01 January 1990
In vivo comparative study of the cytotoxicity of a liposomal formulation of cisplatin (lipoplatin™).

scientific article published on 16 February 2011
Low-dose oral etoposide in epithelial cancer of the ovary

scientific article published on 01 June 1993
Epidoxorubicin and docetaxel as first-line chemotherapy in patients with advanced breast cancer: a multicentric phase I-II study

scientific article published on 01 August 2000
Chronic oral etoposide in small-cell lung cancer: clinical and pharmacokinetic results

scientific article published on 01 August 1993
Pharmacokinetic interactions of paclitaxel, docetaxel and their vehicles with doxorubicin

scientific article published on 01 April 1999
Changes in doxorubicin distribution and toxicity in mice pretreated with the cyclosporin analogue SDZ PSC 833.

scientific article
Development and validation of a liquid chromatography-tandem mass spectrometry method for the determination of ST1926, a novel oral antitumor agent, adamantyl retinoid derivative, in plasma of patients in a Phase I study

scientific article published on 7 August 2009
Determination of L-asparagine in biological samples in the presence of L-asparaginase

scientific article published on 01 July 1994
Metoclopramide treatment in DBA patients: no complete response in a French prospective study

article
Simultaneous determination of gemcitabine and its main metabolite, dFdU, in plasma of patients with advanced non-small-cell lung cancer by high-performance liquid chromatography-tandem mass spectrometry

scientific article published in February 2008
Concerted escalation of dose and dosing duration in a phase I study of the oral camptothecin gimatecan (ST1481) in patients with advanced solid tumors

scientific article
Clinical and pharmacokinetic study of oral NK611, a new podophyllotoxin derivative.

scientific article

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