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Authors whose works are in public domain in at least one jurisdiction

List of works by Frank Skorpen

1-50 of 94 results

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

scientific article (publication date: 3 April 2008)

A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma

scientific article

Lung cancer susceptibility locus at 5p15.33

scientific article

Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA

scientific article (publication date: 20 February 2003)

Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene

scientific article

Base excision repair of DNA in mammalian cells

scientific article

The 118 A > G polymorphism in the human mu-opioid receptor gene may increase morphine requirements in patients with pain caused by malignant disease

scientific article published in November 2004

The Val158Met polymorphism of the human catechol-O-methyltransferase (COMT) gene may influence morphine requirements in cancer pain patients

scientific article published in July 2005

Exploring joint effects of genes and the clinical efficacy of morphine for cancer pain: OPRM1 and COMT gene

scientific article

hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup

scientific article

Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer

scientific journal article

Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk

scientific article

Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls

scientific article

CUBN is a gene locus for albuminuria

scientific article

Investigation of the fine structure of European populations with applications to disease association studies

scientific article published in December 2008

A sequence in the N-terminal region of human uracil-DNA glycosylase with homology to XPA interacts with the C-terminal part of the 34-kDa subunit of replication protein A

scientific article

Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals

scientific article

Health care providers underestimate symptom intensities of cancer patients: a multicenter European study

scientific article

Regulation of expression of nuclear and mitochondrial forms of human uracil-DNA glycosylase

scientific article

Influence from genetic variability on opioid use for cancer pain: a European genetic association study of 2294 cancer pain patients

scientific article published on 12 March 2011

A novel functional polymorphism in the uridine diphosphate-glucuronosyltransferase 2B7 promoter with significant impact on promoter activity

scientific article published on March 2004

Genetic variation in the catechol-O-methyltransferase (COMT) gene and morphine requirements in cancer patients with pain

scientific article published on 18 December 2008

Uncoupling Protein-2 Participates in Cellular Defense against Oxidative Stress in Clonal β-Cells

article

Morphine glucuronide-to-morphine plasma ratios are unaffected by the UGT2B7 H268Y and UGT1A1*28 polymorphisms in cancer patients on chronic morphine therapy

scientific article published on 13 July 2002

Low copy number DNA template can render polymerase chain reaction error prone in a sequence-dependent manner

scientific article published on February 2005

Properties and functions of human uracil-DNA glycosylase from the UNG gene

scientific article

Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta-analysis: the CARTA consortium

scientific article published on 7 October 2014

Sequence variations in the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene: identification of 10 novel single nucleotide polymorphisms (SNPs) and analysis of their relevance to morphine glucuronidation in cancer patients

article by Holthe M et al published 1 January 2003 in The Pharmacogenomics Journal

Variation in the COMT gene: implications for pain perception and pain treatment

scientific article published on April 2009

Clinical and genetic factors associated with nausea and vomiting in cancer patients receiving opioids

Genetic variability and clinical efficacy of morphine

scientific article

Causal associations of tobacco smoking with cardiovascular risk factors: a Mendelian randomization analysis of the HUNT Study in Norway

scientific article published on 26 May 2014

The causal role of smoking in anxiety and depression: a Mendelian randomization analysis of the HUNT study

scientific article published on 12 June 2012

Genetic heterogeneity in latent autoimmune diabetes is linked to various degrees of autoimmune activity: results from the Nord-Trøndelag Health Study

scientific article

Lung cancer and DNA repair genes: multilevel association analysis from the International Lung Cancer Consortium

scientific article published in March 2012

Human uracil-DNA glycosylase gene: sequence organization, methylation pattern, and mapping to chromosome 12q23-q24.1

scientific article

High Systolic Blood Pressure Is Associated With Val/Val Genotype in the Catechol-O-Methyltransferase GeneThe Nord-Trøndelag Health Study (HUNT)

article published in 2007

Common variants show predicted polygenic effects on height in the tails of the distribution, except in extremely short individuals

scientific article

No association between chronic musculoskeletal complaints and Val158Met polymorphism in the Catechol-O-methyltransferase gene. The HUNT study

scientific article published on 4 May 2006

The association between headache and Val158Met polymorphism in the catechol-O-methyltransferase gene: the HUNT Study

scientific article

Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling

scientific article

A low COMT activity haplotype is associated with recurrent preeclampsia in a Norwegian population cohort (HUNT2)

scientific article

Identification of possible genetic polymorphisms involved in cancer cachexia: a systematic review

scientific article published on April 2011

Variable response to opioid treatment: any genetic predictors within sight?

scientific article published on June 2008

Evidence that changes in Se-glutathione peroxidase levels affect the sensitivity of human tumour cell lines to n-3 fatty acids

scientific article published on October 1997

Association between a 15q25 gene variant, nicotine-related habits, lung cancer and COPD among 56,307 individuals from the HUNT study in Norway

scientific article published on 27 February 2013

Depression and anxiety in relation to catechol-O-methyltransferase Val158Met genotype in the general population: the Nord-Trøndelag Health Study (HUNT).

scientific article

Multiple Loci modulate opioid therapy response for cancer pain

scientific article

Induction of uncoupling protein 2 mRNA in beta-cells is stimulated by oxidation of fatty acids but not by nutrient oversupply

scientific article published in April 2002

Time dynamics of autoantibodies are coupled to phenotypes and add to the heterogeneity of autoimmune diabetes in adults: the HUNT study, Norway

article