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List of works by Ormond Macdougald

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Inhibition of adipogenesis by Wnt signaling

scientific article
Regulation of bone mass by Wnt signaling

scientific article
TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth

scientific article
p53-mediated activation of miRNA34 candidate tumor-suppressor genes.

scientific article
Regulation of osteoblastogenesis and bone mass by Wnt10b

scientific journal article
Regulation of Wnt signaling during adipogenesis

scientific article
The role of C/EBP genes in adipocyte differentiation

scientific article published in November 1998
Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis

scientific article published on March 13, 2012
Regulated expression of the obese gene product (leptin) in white adipose tissue and 3T3-L1 adipocytes.

scientific article
Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation

scientific article
Wnt10b inhibits development of white and brown adipose tissues

scientific article published on 9 June 2004
Adipogenesis: forces that tip the scales

scientific article published on January 1, 2002
Wnt6, Wnt10a and Wnt10b inhibit adipogenesis and stimulate osteoblastogenesis through a β-catenin-dependent mechanism.

scientific article published on 18 August 2011
Adipose tissue stem cells meet preadipocyte commitment: going back to the future

scientific article published on December 2, 2011
Bone marrow adipose tissue is an endocrine organ that contributes to increased circulating adiponectin during caloric restriction

scientific article
Wnt signaling stimulates osteoblastogenesis of mesenchymal precursors by suppressing CCAAT/enhancer-binding protein alpha and peroxisome proliferator-activated receptor gamma

scientific article published on 10 March 2007
Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans

scientific article
Wnt10b increases postnatal bone formation by enhancing osteoblast differentiation

scientific journal article
Marrow fat and bone--new perspectives

scientific article
Roles for miRNA-378/378* in adipocyte gene expression and lipogenesis

scientific article
Wnt/beta-catenin signaling in adipogenesis and metabolism.

scientific article published on 9 November 2007
Wnt signaling protects 3T3-L1 preadipocytes from apoptosis through induction of insulin-like growth factors

scientific article
Region-specific variation in the properties of skeletal adipocytes reveals regulated and constitutive marrow adipose tissues

scientific article
Wnt signaling inhibits adipogenesis through beta-catenin-dependent and -independent mechanisms.

scientific article
Fat-specific protein 27 regulates storage of triacylglycerol

scientific article published on 11 March 2008
Wnt10b inhibits obesity in ob/ob and agouti mice.

scientific article published on February 2007
Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis

scientific article
Critical role for hypothalamic mTOR activity in energy balance

scientific article published on April 2009
Quantifying size and number of adipocytes in adipose tissue.

scientific article
Wnt10b deficiency promotes coexpression of myogenic and adipogenic programs in myoblasts

scientific journal article
Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: A novel mouse model for scleroderma?

scientific article published on June 1, 2011
LXRbeta is required for adipocyte growth, glucose homeostasis, and beta cell function

scientific article published on 13 April 2005
Signaling pathways through which insulin regulates CCAAT/enhancer binding protein alpha (C/EBPalpha) phosphorylation and gene expression in 3T3-L1 adipocytes. Correlation with GLUT4 gene expression

scientific article published on October 1997
A High Fat Diet Increases Bone Marrow Adipose Tissue (MAT) But Does Not Alter Trabecular or Cortical Bone Mass in C57BL/6J Mice.

scientific article
Secreted frizzled-related protein 5 suppresses adipocyte mitochondrial metabolism through WNT inhibition

scientific article
Obese gene expression at in vivo levels by fat pads derived from s.c. implanted 3T3-F442A preadipocytes

scientific article
Multiple roles for the non-coding RNA SRA in regulation of adipogenesis and insulin sensitivity.

scientific article
Use of osmium tetroxide staining with microcomputerized tomography to visualize and quantify bone marrow adipose tissue in vivo

scientific article
Transcriptional control of the stearoyl-CoA desaturase-1 gene by polyunsaturated fatty acids

scientific article published on 01 April 1994
Growth hormone regulates phosphorylation and function of CCAAT/enhancer-binding protein beta by modulating Akt and glycogen synthase kinase-3.

scientific article published on 13 March 2001
Critical roles for the TSC-mTOR pathway in β-cell function

scientific article published on 18 August 2009
Reciprocal Control of Osteogenic and Adipogenic Differentiation by ERK/MAP Kinase Phosphorylation of Runx2 and PPARγ Transcription Factors

scientific article published on 23 July 2015
The rapidly expanding family of adipokines

scientific article published on 01 September 2007
Adipose tissue stem cells: the great WAT hope

scientific article published on March 12, 2012
T-cell factor 4N (TCF-4N), a novel isoform of mouse TCF-4, synergizes with beta-catenin to coactivate C/EBPalpha and steroidogenic factor 1 transcription factors

scientific article
Inhibitor of DNA binding 2 is a small molecule-inducible modulator of peroxisome proliferator-activated receptor-gamma expression and adipocyte differentiation

scientific journal article
Syndecan-1 is required to maintain intradermal fat and prevent cold stress

scientific article
Artificial sweeteners stimulate adipogenesis and suppress lipolysis independently of sweet taste receptors

scientific article published on 24 September 2013
The transcription factor paired-related homeobox 1 (Prrx1) inhibits adipogenesis by activating transforming growth factor-β (TGFβ) signaling

scientific article
On the role of FOX transcription factors in adipocyte differentiation and insulin-stimulated glucose uptake

scientific article published on 24 February 2009

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