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List of works by Mario P. Tschan

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article
Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article
The transcription factor encyclopedia

scientific article (publication date: 2012)
T-cell protection and enrichment through lentiviral CCR5 intrabody gene delivery.

scientific article
Reliable LC3 and p62 autophagy marker detection in formalin fixed paraffin embedded human tissue by immunohistochemistry

scientific article published on 5 May 2015
p73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene.

scientific article published on 02 August 2013
Antitumor effect of SIRT1 inhibition in human HCC tumor models in vitro and in vivo.

scientific article published on 21 January 2013
WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy

scientific article
Inhibition of SIRT1 impairs the accumulation and transcriptional activity of HIF-1α protein under hypoxic conditions

scientific article
MicroRNA-29b is involved in the Src-ID1 signaling pathway and is dysregulated in human lung adenocarcinoma

scientific article published on January 16, 2012
Scavenger chemokine (CXC motif) receptor 7 (CXCR7) is a direct target gene of HIC1 (hypermethylated in cancer 1).

scientific article published on 12 June 2009
Alternative splicing of the human cyclin D-binding Myb-like protein (hDMP1) yields a truncated protein isoform that alters macrophage differentiation patterns

scientific article
MicroRNA-381 represses ID1 and is deregulated in lung adenocarcinoma

scientific article published on 01 July 2012
Prognostic value of the autophagy markers LC3 and p62/SQSTM1 in early-stage non-small cell lung cancer.

scientific article published on 26 May 2016
Enhanced p73 expression during differentiation and complex p73 isoforms in myeloid leukemia

scientific article published on 01 October 2000
Activated tumor cell integrin αvβ3 cooperates with platelets to promote extravasation and metastasis from the blood stream

scientific article
Deregulated expression of Kruppel-like factors in acute myeloid leukemia

scientific article
miR-125b controls apoptosis and temozolomide resistance by targeting TNFAIP3 and NKIRAS2 in glioblastomas

scientific article
NDRG1/2 expression is inhibited in primary acute myeloid leukemia

scientific article published on 22 September 2009
Identification of the p53 family-responsive element in the promoter region of the tumor suppressor gene hypermethylated in cancer 1

scientific article
Epigallocatechin-3-gallate induces cell death in acute myeloid leukaemia cells and supports all-trans retinoic acid-induced neutrophil differentiation via death-associated protein kinase 2.

scientific article published on 20 January 2010
miR-29b Mediates NF-κB Signaling in KRAS-Induced Non-Small Cell Lung Cancers.

scientific article published on 19 May 2016
p62/SQSTM1 upregulation constitutes a survival mechanism that occurs during granulocytic differentiation of acute myeloid leukemia cells.

scientific article
WIPI-dependent autophagy during neutrophil differentiation of NB4 acute promyelocytic leukemia cells.

scientific article
Synergistic induction of cell death in liver tumor cells by TRAIL and chemotherapeutic drugs via the BH3-only proteins Bim and Bid

scientific article
The role of autophagy in anticancer therapy: promises and uncertainties

scientific article published on 22 October 2010
Lipid droplet and early autophagosomal membrane targeting of Atg2A and Atg14L in human tumor cells

scientific article
Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation

scientific article published on 15 May 2015
HIC1 tumour suppressor gene is suppressed in acute myeloid leukaemia and induced during granulocytic differentiation

scientific article published on 3 March 2008
The death-associated protein kinase 2 is up-regulated during normal myeloid differentiation and enhances neutrophil maturation in myeloid leukemic cells

scientific article
Protective autophagy is involved in resistance towards MET inhibitors in human gastric adenocarcinoma cells.

scientific article published on 9 January 2013
Overexpression of the p73 gene is a novel finding in high-risk B-cell chronic lymphocytic leukemia

scientific article published in July 2001
Differential expression of p73 splice variants and protein in benign and malignant ovarian tumours

scientific article published on 01 October 2000
The tumor suppressor gene hypermethylated in cancer 1 is transcriptionally regulated by E2F1.

scientific article
The stem cell gene "inhibitor of differentiation 1" (ID1) is frequently expressed in non-small cell lung cancer

scientific article
CLEC5A (MDL-1) is a novel PU.1 transcriptional target during myeloid differentiation

scientific article
Prognostic relevance of autophagy markers LC3B and p62 in esophageal adenocarcinomas

scientific article published on 26 May 2016
The anti-apoptotic gene BCL2A1 is a novel transcriptional target of PU.1.

scientific article published on 4 March 2010
Targeting the phosphoinositide 3-kinase p110-α isoform impairs cell proliferation, survival, and tumor growth in small cell lung cancer.

scientific article published on 21 November 2012
Human DMTF1β antagonizes DMTF1α regulation of the p14(ARF) tumor suppressor and promotes cellular proliferation.

scientific article
PU.1 binding to the p53 family of tumor suppressors impairs their transcriptional activity.

scientific article published on 14 January 2008
Inhibition of the miR-143/145 cluster attenuated neutrophil differentiation of APL cells

scientific article published on 16 November 2011
Inhibition of GATE-16 attenuates ATRA-induced neutrophil differentiation of APL cells and interferes with autophagosome formation

scientific article
CEBPA-dependent HK3 and KLF5 expression in primary AML and during AML differentiation

scientific article
DAPK2 is a novel E2F1/KLF6 target gene involved in their proapoptotic function

scientific article published on 2 June 2008
Inhibition of damage-regulated autophagy modulator-1 (DRAM-1) impairs neutrophil differentiation of NB4 APL cells.

scientific article
Modulation of drug resistance by artificial transcription factors.

scientific article
The cyclin-dependent kinase inhibitors p18INK4c and p19INK4d are highly expressed in CD34+ progenitor and acute myeloid leukaemic cells but not in normal differentiated myeloid cells

scientific article published on 01 September 1999
Aberrant FHIT mRNA transcripts are present in malignant and normal haematopoiesis, but absence of FHIT protein is restricted to leukaemia

scientific article published on 01 January 1999
The RNA binding proteins RBM38 and DND1 are repressed in AML and have a novel function in APL differentiation

scientific article published on 19 December 2015

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