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List of works by Antonello Di Paolo

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Pharmacodynamic and pharmacogenetic angiogenesis-related markers of first-line FOLFOXIRI plus bevacizumab schedule in metastatic colorectal cancer

scientific article
Relationship between 5-fluorouracil disposition, toxicity and dihydropyrimidine dehydrogenase activity in cancer patients

scientific article published in September 2001
Biweekly chemotherapy with oxaliplatin, irinotecan, infusional Fluorouracil, and leucovorin: a pilot study in patients with metastatic colorectal cancer

scientific article published in October 2002
Clinical, pharmacokinetic and pharmacodynamic evaluations of metronomic UFT and cyclophosphamide plus celecoxib in patients with advanced refractory gastrointestinal cancers

scientific article published on 2 March 2012
5-fluorouracil pharmacokinetics predicts disease-free survival in patients administered adjuvant chemotherapy for colorectal cancer.

scientific article published in May 2008
A pharmacokinetic and pharmacodynamic study on metronomic irinotecan in metastatic colorectal cancer patients.

scientific article published on 25 March 2008
Oral gentamicin gut decontamination for prevention of KPC-producing Klebsiella pneumoniae infections: relevance of concomitant systemic antibiotic therapy

scientific article
The c.480C>G polymorphism of hOCT1 influences imatinib clearance in patients affected by chronic myeloid leukemia

scientific article published on 04 March 2014
Pharmacokinetic and pharmacogenetic predictive markers of irinotecan activity and toxicity.

scientific article published on December 2011
Lack of pharmacokinetic bioequivalence between generic and branded amoxicillin formulations. A post-marketing clinical study on healthy volunteers.

scientific article published on July 2009
Thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase expression in colorectal cancer and normal mucosa in patients

scientific article published on 01 November 2006
Pharmacokinetic interactions between omeprazole/pantoprazole and clarithromycin in health volunteers

scientific article published in May 2004
A pharmacokinetic-based test to prevent severe 5-fluorouracil toxicity

scientific article published on 01 October 2006
ABCB1 polymorphisms are associated with clozapine plasma levels in psychotic patients

scientific article published in August 2009
EGFR ligands as pharmacodynamic biomarkers in metastatic colorectal cancer patients treated with cetuximab and irinotecan.

scientific article published on 3 July 2013
Pharmacogenetic determinants of anti-cancer drug activity and toxicity.

scientific article
An improved HPLC method for therapeutic drug monitoring of daunorubicin, idarubicin, doxorubicin, epirubicin, and their 13-dihydro metabolites in human plasma

scientific article published on 01 June 1999
Pharmacokinetics and pharmacodynamics of combination chemotherapy with paclitaxel and epirubicin in breast cancer patients

scientific article published on May 2002
Pharmacokinetics of azithromycin in lung tissue, bronchial washing, and plasma in patients given multiple oral doses of 500 and 1000 mg daily

scientific article published in December 2002
Irinotecan synergistically enhances the antiproliferative and proapoptotic effects of axitinib in vitro and improves its anticancer activity in vivo

scientific article published on March 2011
Drug therapeutic failures in emergency department patients. A university hospital experience.

scientific article published in January 2004
Inhibitory effect of suramin in rat models of angiogenesis in vitro and in vivo

scientific article published on 01 January 1999
Relationship between plasma concentrations of 5-fluorouracil and 5-fluoro-5,6-dihydrouracil and toxicity of 5-fluorouracil infusions in cancer patients.

scientific article published in October 2002
Inhibition of protein farnesylation enhances the chemotherapeutic efficacy of the novel geranylgeranyltransferase inhibitor BAL9611 in human colon cancer cells.

scientific article published on June 2001
Clinical and experimental pharmacokinetic interaction between 6-mercaptopurine and methotrexate

scientific article published on 01 January 1996
A rapid high-performance liquid chromatography method to measure linezolid and daptomycin concentrations in human plasma

scientific article published in April 2010
The role of thymidylate synthase as a molecular biomarker

scientific article published on 01 January 2004
Limited sampling model for the analysis of 5-fluorouracil pharmacokinetics in adjuvant chemotherapy for colorectal cancer

scientific article
Micafungin for Candida albicans pacemaker-associated endocarditis: a case report and review of the literature

scientific article published on 17 October 2012
Case report of a successful treatment of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia and MRSA/vancomycin-resistant Enterococcus faecium cholecystitis by daptomycin.

scientific article published on 22 February 2011
A phase I and pharmacokinetic study of irinotecan given as a 7-day continuous infusion in metastatic colorectal cancer patients pretreated with 5-fluorouracil or raltitrexed.

scientific article published in March 2004
Clinical pharmacokinetics of antibacterials in cerebrospinal fluid.

scientific article published on July 2013
Population pharmacokinetics of daptomycin in patients affected by severe Gram-positive infections.

scientific article published on 25 July 2013
Linezolid for endocarditis: a case series of 14 patients

scientific article published on 11 January 2011
Dihydropyrimidine dehydrogenase polymorphisms and fluoropyrimidine toxicity: ready for routine clinical application within personalized medicine?

scientific article
Personalized medicine in Europe: not yet personal enough?

scientific article
Daptomycin concentrations in valve tissue and vegetation in patients with bacterial endocarditis

scientific article published on 22 October 2012
An exploratory study on pharmacogenetics of inosine-monophosphate dehydrogenase II in peripheral mononuclear cells from liver-transplant recipients.

scientific article published in November 2004
Cardiovascular implantable electronic device endocarditis treated with daptomycin with or without transvenous removal.

scientific article published on 20 March 2012
A dose finding and pharmacokinetic study of capecitabine in combination with oxaliplatin and irinotecan in metastatic colorectal cancer.

scientific article published on 7 October 2008
Population pharmacokinetic analysis of 5-FU and 5-FDHU in colorectal cancer patients: search for biomarkers associated with gastro-intestinal toxicity

scientific article published on 01 January 2012
In vitro and in vivo antitumour effects of novel, orally active bile acid-conjugated platinum complexes on rat hepatoma

scientific article published on 16 August 2006
Pharmacokinetics, a main actor in a many-sided approach to severe 5-FU toxicity prediction

scientific article published on 5 November 2008
Severe 5-fluorouracil toxicity associated with a marked alteration of pharmacokinetics of 5-fluorouracil and its catabolite 5-fluoro-5,6-dihydrouracil: a case report.

scientific article published on December 2002
Irinotecan in combination with thalidomide in patients with advanced solid tumors: a clinical study with pharmacodynamic and pharmacokinetic evaluation.

scientific article published on 6 May 2006
Association of the hOCT1/ABCB1 genotype with efficacy and tolerability of imatinib in patients affected by chronic myeloid leukemia.

scientific article
Acetylcholinesterase blockade does not account for the adverse cardiovascular effects of the antitumor drug irinotecan: a preclinical study.

scientific article published in December 2001
Serotonin syndrome and the T102-->C polymorphism of the 5-HT2A receptor: a case report

scientific article published in July 2008
A phase I study of continuous hepatic arterial infusion of Irinotecan in patients with locally advanced hepatocellular carcinoma

scientific article published on 13 September 2011
Improved analysis of 5-Fluorouracil and 5,6-dihydro-5-Fluorouracil by HPLC with diode array detection for determination of cellular dihydropyrimidine dehydrogenase activity and pharmacokinetic profiling

scientific article published in June 2005

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