List of works - Heinz Sill

Complex tumor genomes inferred from single circulating tumor cells by array-CGH and next-generation sequencing

scientific article

PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanismsin haematological malignancies

scientific article published on 01 February 1999

Establishment of tumor-specific copy number alterations from plasma DNA of patients with cancer.

scientific article

BAALC, the human member of a novel mammalian neuroectoderm gene lineage, is implicated in hematopoiesis and acute leukemia

scientific article

Treatment of chronic myelogenous leukemia with the tyrosine kinase inhibitor STI571 results in marked regression of bone marrow fibrosis

scientific article published in January 2002

Signaling through RAS-RAF-MEK-ERK: from basics to bedside.

scientific article published on January 2007

Two transforming C-RAF germ-line mutations identified in patients with therapy-related acute myeloid leukemia

scientific article

Germline mutations in the DNA damage response genes BRCA1, BRCA2, BARD1 and TP53 in patients with therapy related myeloid neoplasms.

scientific article

Prolonged monitoring of troponin T for the detection of anthracycline cardiotoxicity in adults with hematological malignancies

scientific article published on 25 March 2003

Contaminated handwashing sinks as the source of a clonal outbreak of KPC-2-producing Klebsiella oxytoca on a hematology ward

scientific article

Repeated fecal microbiota transplantations attenuate diarrhea and lead to sustained changes in the fecal microbiota in acute, refractory gastrointestinal graft-versus-host-disease

scientific article published on 2 February 2017

Homozygous deletions of the p16 tumor-suppressor gene are associated with lymphoid transformation of chronic myeloid leukemia.

scientific article

Posaconazole plasma concentrations and invasive mould infections in patients with haematological malignancies.

scientific article published on 3 April 2012

Therapy-related myeloid neoplasms: pathobiology and clinical characteristics

scientific article

Common alterations in gene expression and increased proliferation in recurrent acute myeloid leukemia

article

Frequency, onset and clinical impact of somatic DNMT3A mutations in therapy-related and secondary acute myeloid leukemia

scientific article published on 11 October 2011

Germline variants in the SEMA4A gene predispose to familial colorectal cancer type X.

scientific article

Iron overload in myelodysplastic syndromes (MDS) - diagnosis, management, and response criteria: a proposal of the Austrian MDS platform

scientific article published on 24 January 2008

A microRNA-mediated regulatory loop modulates NOTCH and MYC oncogenic signals in B- and T-cell malignancies

scientific article

RT-PCR and FISH analysis of acute myeloid leukemia with t(8;16)(p11;p13) and chimeric MOZ and CBP transcripts: breakpoint cluster region and clinical implications

scientific article

Loss of RAF kinase inhibitor protein is a somatic event in the pathogenesis of therapy-related acute myeloid leukemias with C-RAF germline mutations.

scientific article published on 9 April 2009

Overexpression of primary microRNA 221/222 in acute myeloid leukemia

scientific article

Monitoring of cardiac function by serum cardiac troponin T levels, ventricular repolarisation indices, and echocardiography after conditioning with fractionated total body irradiation and high-dose cyclophosphamide

scientific article published on 01 July 2002

Epidemiology of invasive fungal infections and rationale for antifungal therapy in patients with haematological malignancies

scientific article published on 6 April 2010

IDH Mutation, Competitive Inhibition of FTO, and RNA Methylation

scientific article published in May 2017

Increased Expression of miR-23a Mediates a Loss of Expression in the RAF Kinase Inhibitor Protein RKIP.

scientific article

Identification of CD25 as STAT5-Dependent Growth Regulator of Leukemic Stem Cells in Ph+ CML.

scientific article published on 25 November 2015

A functional single-nucleotide polymorphism of the G-CSF receptor gene predisposes individuals to high-risk myelodysplastic syndrome

article

Defective DNA-mismatch repair: a potential mediator of leukemogenic susceptibility in therapy-related myelodysplasia and leukemia.

scientific article published in June 2002

Frequent loss of RAF kinase inhibitor protein expression in acute myeloid leukemia

scientific article

Long-term treatment with imatinib results in profound mast cell deficiency in Ph+ chronic myeloid leukemia

scientific article published on February 2015

Rituximab (anti-CD20 monoclonal antibody) as consolidation of first-line CHOP chemotherapy in patients with follicular lymphoma: a phase II study

scientific article published in July 2002

Restoration of erythropoiesis by rituximab in an adult patient with primary acquired pure red cell aplasia refractory to conventional treatment

scientific article published on 01 March 2002

D2HGDH regulates alpha-ketoglutarate levels and dioxygenase function by modulating IDH2

scientific article published on 16 July 2015

Adoptive transfer of vitiligo after allogeneic bone marrow transplantation for non-Hodgkin's lymphoma

scientific article published in The Lancet

Therapeutic Resistance in Acute Myeloid Leukemia: The Role of Non-Coding RNAs

scientific article

Somatic TP53 mutations characterize preleukemic stem cells in acute myeloid leukemia.

scientific article

Rarity of dominant-negative mutations of the G-CSF receptor in patients with blast crisis of chronic myeloid leukemia or de novo acute leukemia

scientific article published in July 1997

Preexisting TP53 mutation in therapy-related acute myeloid leukemia

scientific article published on 20 August 2014

Azacitidine front-line in 339 patients with myelodysplastic syndromes and acute myeloid leukaemia: comparison of French-American-British and World Health Organization classifications

scientific article published on 16 April 2016

Acute myeloid leukemia with TP53 germ line mutations.

scientific article published on 12 September 2016

Rarity of microsatellite alterations in acute myeloid leukaemia.

scientific article published on July 1996

Azacitidine for Front-Line Therapy of Patients with AML: Reproducible Efficacy Established by Direct Comparison of International Phase 3 Trial Data with Registry Data from the Austrian Azacitidine Registry of the AGMT Study Group

scientific article

Hepatic veno-occlusive disease in two patients with relapsed acute myeloid leukemia treated with anti-CD33 calicheamicin (CMA-676) immunoconjugate

scientific article published on 01 February 2001

Pulmonary infiltrates in patients with haematologic malignancies: transbronchial lung biopsy increases the diagnostic yield with respect to neoplastic infiltrates and toxic pneumonitis

article

Interferon-alpha-2C and LD ara-C for the treatment of patients with CML: Results of the austrian multicenter phase II study

scientific article published on 01 January 1997

Cytarabine dose in the consolidation treatment of AML: a systematic review and meta-analysis

scientific article

Aberrant transcripts of the FHIT gene are expressed in normal and leukaemic haemopoietic cells

scientific article published on September 1, 1998

Angiotropic large cell lymphoma presenting as thrombotic microangiopathy (thrombotic thrombocytopenic purpura).

scientific article

microRNAs in acute myeloid leukemia: expression patterns, correlations with genetic and clinical parameters, and prognostic significance

scientific article published on March 2010

List of works by Heinz Sill

Complex tumor genomes inferred from single circulating tumor cells by array-CGH and next-generation sequencing

PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanismsin haematological malignancies

Establishment of tumor-specific copy number alterations from plasma DNA of patients with cancer.

BAALC, the human member of a novel mammalian neuroectoderm gene lineage, is implicated in hematopoiesis and acute leukemia

Treatment of chronic myelogenous leukemia with the tyrosine kinase inhibitor STI571 results in marked regression of bone marrow fibrosis

Signaling through RAS-RAF-MEK-ERK: from basics to bedside.

Two transforming C-RAF germ-line mutations identified in patients with therapy-related acute myeloid leukemia

Germline mutations in the DNA damage response genes BRCA1, BRCA2, BARD1 and TP53 in patients with therapy related myeloid neoplasms.

Prolonged monitoring of troponin T for the detection of anthracycline cardiotoxicity in adults with hematological malignancies

Contaminated handwashing sinks as the source of a clonal outbreak of KPC-2-producing Klebsiella oxytoca on a hematology ward

Repeated fecal microbiota transplantations attenuate diarrhea and lead to sustained changes in the fecal microbiota in acute, refractory gastrointestinal graft-versus-host-disease

Homozygous deletions of the p16 tumor-suppressor gene are associated with lymphoid transformation of chronic myeloid leukemia.

Posaconazole plasma concentrations and invasive mould infections in patients with haematological malignancies.

Therapy-related myeloid neoplasms: pathobiology and clinical characteristics

Common alterations in gene expression and increased proliferation in recurrent acute myeloid leukemia

Frequency, onset and clinical impact of somatic DNMT3A mutations in therapy-related and secondary acute myeloid leukemia

Germline variants in the SEMA4A gene predispose to familial colorectal cancer type X.

Iron overload in myelodysplastic syndromes (MDS) - diagnosis, management, and response criteria: a proposal of the Austrian MDS platform

A microRNA-mediated regulatory loop modulates NOTCH and MYC oncogenic signals in B- and T-cell malignancies

RT-PCR and FISH analysis of acute myeloid leukemia with t(8;16)(p11;p13) and chimeric MOZ and CBP transcripts: breakpoint cluster region and clinical implications

Loss of RAF kinase inhibitor protein is a somatic event in the pathogenesis of therapy-related acute myeloid leukemias with C-RAF germline mutations.

Overexpression of primary microRNA 221/222 in acute myeloid leukemia

Monitoring of cardiac function by serum cardiac troponin T levels, ventricular repolarisation indices, and echocardiography after conditioning with fractionated total body irradiation and high-dose cyclophosphamide

Epidemiology of invasive fungal infections and rationale for antifungal therapy in patients with haematological malignancies

IDH Mutation, Competitive Inhibition of FTO, and RNA Methylation

Increased Expression of miR-23a Mediates a Loss of Expression in the RAF Kinase Inhibitor Protein RKIP.

Identification of CD25 as STAT5-Dependent Growth Regulator of Leukemic Stem Cells in Ph+ CML.

A functional single-nucleotide polymorphism of the G-CSF receptor gene predisposes individuals to high-risk myelodysplastic syndrome

Defective DNA-mismatch repair: a potential mediator of leukemogenic susceptibility in therapy-related myelodysplasia and leukemia.

Frequent loss of RAF kinase inhibitor protein expression in acute myeloid leukemia

Long-term treatment with imatinib results in profound mast cell deficiency in Ph+ chronic myeloid leukemia

Rituximab (anti-CD20 monoclonal antibody) as consolidation of first-line CHOP chemotherapy in patients with follicular lymphoma: a phase II study

Restoration of erythropoiesis by rituximab in an adult patient with primary acquired pure red cell aplasia refractory to conventional treatment

D2HGDH regulates alpha-ketoglutarate levels and dioxygenase function by modulating IDH2

Adoptive transfer of vitiligo after allogeneic bone marrow transplantation for non-Hodgkin's lymphoma

Therapeutic Resistance in Acute Myeloid Leukemia: The Role of Non-Coding RNAs

Somatic TP53 mutations characterize preleukemic stem cells in acute myeloid leukemia.

Rarity of dominant-negative mutations of the G-CSF receptor in patients with blast crisis of chronic myeloid leukemia or de novo acute leukemia

Preexisting TP53 mutation in therapy-related acute myeloid leukemia

Azacitidine front-line in 339 patients with myelodysplastic syndromes and acute myeloid leukaemia: comparison of French-American-British and World Health Organization classifications

Acute myeloid leukemia with TP53 germ line mutations.

Rarity of microsatellite alterations in acute myeloid leukaemia.

Azacitidine for Front-Line Therapy of Patients with AML: Reproducible Efficacy Established by Direct Comparison of International Phase 3 Trial Data with Registry Data from the Austrian Azacitidine Registry of the AGMT Study Group

Hepatic veno-occlusive disease in two patients with relapsed acute myeloid leukemia treated with anti-CD33 calicheamicin (CMA-676) immunoconjugate

Pulmonary infiltrates in patients with haematologic malignancies: transbronchial lung biopsy increases the diagnostic yield with respect to neoplastic infiltrates and toxic pneumonitis

Interferon-alpha-2C and LD ara-C for the treatment of patients with CML: Results of the austrian multicenter phase II study

Cytarabine dose in the consolidation treatment of AML: a systematic review and meta-analysis

Aberrant transcripts of the FHIT gene are expressed in normal and leukaemic haemopoietic cells

Angiotropic large cell lymphoma presenting as thrombotic microangiopathy (thrombotic thrombocytopenic purpura).

microRNAs in acute myeloid leukemia: expression patterns, correlations with genetic and clinical parameters, and prognostic significance