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List of works by Leonid Padyukov

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Genetics of rheumatoid arthritis contributes to biology and drug discovery

scientific article
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

scientific article
A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination

scientific article published on January 2006
STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus

scientific article published on September 2007
A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

scientific article
TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study

scientific article
Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis

scientific article
Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

scientific article
Genome-wide association identifies multiple ulcerative colitis susceptibility loci

scientific article
Two independent alleles at 6q23 associated with risk of rheumatoid arthritis

scientific article
Common variants at CD40 and other loci confer risk of rheumatoid arthritis

scientific article published on 14 September 2008
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

scientific article
A gene-environment interaction between smoking and shared epitope genes in HLA-DR provides a high risk of seropositive rheumatoid arthritis

scientific article
Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4

scientific article
Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018
Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk

scientific article
Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus

scientific article
Immunity to citrullinated proteins in rheumatoid arthritis

scientific article
Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking in two subsets of rheumatoid arthritis

scientific article published on 2 April 2007
MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction

scientific journal article
Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.

scientific article
Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population

scientific journal article
Specific interaction between genotype, smoking and autoimmunity to citrullinated alpha-enolase in the etiology of rheumatoid arthritis

scientific article
A genome-wide association study of anorexia nervosa

scientific article
Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases

scientific article published on 21 October 2009
A candidate gene approach identifies the TRAF1/C5 region as a risk factor for rheumatoid arthritis

scientific article
Smoking is a major preventable risk factor for rheumatoid arthritis: estimations of risks after various exposures to cigarette smoke

scientific article
A combination of autoantibodies to cyclic citrullinated peptide (CCP) and HLA-DRB1 locus antigens is strongly associated with future onset of rheumatoid arthritis

scientific article
A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis

scientific article
Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy

scientific article
A role for noncoding variation in schizophrenia

scientific article
Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritis

article
Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis

scientific article
Smoking, citrullination and genetic variability in the immunopathogenesis of rheumatoid arthritis

scientific article published on 03 March 2011
Alcohol consumption is associated with decreased risk of rheumatoid arthritis: results from two Scandinavian case-control studies

scientific article
Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis

scientific article published on January 2014
Increased expression of the novel proinflammatory cytokine high mobility group box chromosomal protein 1 in skin lesions of patients with lupus erythematosus

article
Multiple antibody reactivities to citrullinated antigens in sera from patients with rheumatoid arthritis: association with HLA-DRB1 alleles

scientific article published on 17 July 2008
Fine mapping seronegative and seropositive rheumatoid arthritis to shared and distinct HLA alleles by adjusting for the effects of heterogeneity.

scientific article published on 20 March 2014
Copy number, linkage disequilibrium and disease association in the FCGR locus

scientific article
Protection against anti-citrullinated protein antibody-positive rheumatoid arthritis is predominantly associated with HLA-DRB1*1301: a meta-analysis of HLA-DRB1 associations with anti-citrullinated protein antibody-positive and anti-citrullinated pr

scientific article
Mechanisms of disease: Genetic susceptibility and environmental triggers in the development of rheumatoid arthritis

scientific article published on August 2006
Genetic markers for the efficacy of tumour necrosis factor blocking therapy in rheumatoid arthritis

scientific article published on June 2003
Genetic and environmental determinants for disease risk in subsets of rheumatoid arthritis defined by the anticitrullinated protein/peptide antibody fine specificity profile

scientific article
Smoking as a trigger for inflammatory rheumatic diseases

scientific article published on January 2007
Association of the PD-1.3A allele of the PDCD1 gene in patients with rheumatoid arthritis negative for rheumatoid factor and the shared epitope

scientific article
Different patterns of associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in the extended major histocompatibility complex region

scientific article
Genes, environment and immunity in the development of rheumatoid arthritis

scientific article published on 28 September 2006
Gene-environment interaction between the DRB1 shared epitope and smoking in the risk of anti-citrullinated protein antibody-positive rheumatoid arthritis: all alleles are important

scientific article published on June 2009
Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa.

scientific article

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