List of works - Xavier León

HPV Involvement in Head and Neck Cancers: Comprehensive Assessment of Biomarkers in 3680 Patients

scientific article published on 28 January 2016

Overview of the efficacy of cetuximab in recurrent and/or metastatic squamous cell carcinoma of the head and neck in patients who previously failed platinum-based therapies

scientific article published in June 2008

An anatomical study of anastomoses between the laryngeal nerves.

scientific article

A retrospective analysis of the outcome of patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck refractory to a platinum-based chemotherapy

scientific article published on 01 September 2005

Influence of the persistence of tobacco and alcohol use in the appearance of second neoplasm in patients with a head and neck cancer. A case-control study

scientific article

Variability in nerve patterns of the adductor muscle group supplied by the recurrent laryngeal nerve.

scientific article

Pretreatment count of peripheral neutrophils, monocytes, and lymphocytes as independent prognostic factor in patients with head and neck cancer

scientific article

Selective dissection of levels II-III with intraoperative control of the upper and middle jugular nodes: A therapeutic option for the no neck

scientific article published on 01 June 2001

Salvage surgery after locoregional failure in head and neck carcinoma patients treated with chemoradiotherapy.

scientific article published on 19 August 2010

uPA/uPAR and SERPINE1 in head and neck cancer: role in tumor resistance, metastasis, prognosis and therapy

scientific article

Prostaglandin E(2) pathway in head and neck squamous cell carcinoma

scientific article published in September 2008

Interaction between head and neck squamous cell carcinoma cells and fibroblasts in the biosynthesis of PGE2.

scientific article published on 4 February 2012

Enhanced cell migration and apoptosis resistance may underlie the association between high SERPINE1 expression and poor outcome in head and neck carcinoma patients.

scientific article published on 24 August 2015

Tumor cells induce COX-2 and mPGES-1 expression in microvascular endothelial cells mainly by means of IL-1 receptor activation.

scientific article published on 26 January 2011

Metachronous second primary tumours in the aerodigestive tract in patients with early stage head and neck squamous cell carcinomas

scientific article published on 13 May 2005

Ku70 predicts response and primary tumor recurrence after therapy in locally advanced head and neck cancer.

scientific article published in September 2008

Variability of the nerve supply patterns of the human posterior cricoarytenoid muscle.

scientific article

Gene expression signatures and molecular markers associated with clinical outcome in locally advanced head and neck carcinoma.

scientific article

The effect of waiting time on local control and survival in head and neck carcinoma patients treated with radiotherapy

scientific article

Classification of parotidectomies: a proposal of the European Salivary Gland Society

scientific article

Incidence and significance of clinically unsuspected thyroid tissue in lymph nodes found during neck dissection in head and neck carcinoma patients

scientific article published on 01 March 2005

Human papillomavirus as prognostic marker with rising prevalence in neck squamous cell carcinoma of unknown primary: A retrospective multicentre study.

scientific article published on 10 February 2017

Supracricoid laryngectomy as salvage surgery after failure of radiation therapy

scientific article published on 13 February 2007

Prognostic role of MMP-9 expression in head and neck carcinoma patients treated with radiotherapy or chemoradiotherapy

scientific article

Expression of IL-1α correlates with distant metastasis in patients with head and neck squamous cell carcinoma

scientific article published on 9 October 2015

Second, third, and fourth head and neck tumors. A progressive decrease in survival

scientific article published on 6 February 2012

Potential structures that could be confused with a nonrecurrent inferior laryngeal nerve: an anatomic study

scientific article published on 01 January 2008

The role of HPV on the risk of second primary neoplasia in patients with oropharyngeal carcinoma

scientific article published on 2 December 2016

Laryngeal cancer in non-smoking and non-drinking patients

journal article; published in Acta Oto-Laryngologica in 2004

Prostacyclin-synthase expression in head and neck carcinoma patients and its prognostic value in the response to radiotherapy

scientific article published on January 2015

Parotidectomies in benign parotid tumours: "Sant Pau" surgical extension classification

scientific article

Management of recurrent head and neck cancer: variables related to salvage surgery

scientific article published on 17 May 2016

High RAB25 expression is associated with good clinical outcome in patients with locally advanced head and neck squamous cell carcinoma

scientific article published on 31 October 2013

Overexpression of the nuclear factor-kappa B (p65) in association with local failure in patients with head and neck carcinoma undergong radiotherapy or chemoradiotherapy

scientific article published on 16 March 2012

Prognostic factors in head and neck squamous cell carcinoma: Comparison of CHAID decision trees technology and cox analysis

scientific article published on June 19, 2012

Results of an organ preservation protocol with induction chemotherapy and radiotherapy in patients with locally advanced laryngeal carcinoma

scientific article published on 18 February 2004

Total or subtotal glossectomy with microsurgical reconstruction: functional and oncological results

scientific article published on 23 September 2011

Comparison of the Radiation Therapy Oncology Group recursive partitioning classification and Union Internationale Contre le Cancer TNM classification for patients with head and neck carcinoma

scientific article

Salvage surgery after local recurrence in patients with head and neck carcinoma treated with chemoradiotherapy or bioradiotherapy

scientific article published on 13 November 2014

CKMT1 and NCOA1 expression as a predictor of clinical outcome in patients with advanced-stage head and neck squamous cell carcinoma.

scientific article published on 30 October 2015

External validation of sTWEAK as a prognostic noninvasive biomarker for head and neck squamous cell carcinoma.

scientific article published on 17 December 2015

Low blood levels of sTWEAK are related to locoregional failure in head and neck cancer.

scientific article published on 26 May 2014

Validation of the pathological classification of lymph node metastasis for head and neck tumors according to the 8th edition of the TNM Classification of Malignant Tumors.

scientific article published on 18 May 2017

Foramen thyroideum: a comparative study in embryos, fetuses, and adults

scientific article published on 01 August 1997

Delayed carotid blow-out syndrome: a new complication of chemoradiotherapy treatment in pharyngolaryngeal carcinoma

scientific article published on 11 September 2012

External validation of a risk group defined by recursive partitioning analysis in patients with head and neck carcinoma treated with surgery and postoperative radiotherapy

scientific article

The prognostic value of pretreatment platelet count in patients with head and neck squamous cell carcinoma

scientific article published on 8 July 2016

Competing mortality in oropharyngeal carcinoma according to human papillomavirus status

scientific article published on 14 December 2018

Expression of the CXCL12/CXCR4 chemokine axis predicts regional control in head and neck squamous cell carcinoma.

scientific article

The combined use of EFS, GPX2, and SPRR1A expression could distinguish favorable from poor clinical outcome among epithelial-like head and neck carcinoma subtypes

scientific article published on 16 January 2019

List of works by Xavier León

HPV Involvement in Head and Neck Cancers: Comprehensive Assessment of Biomarkers in 3680 Patients

Overview of the efficacy of cetuximab in recurrent and/or metastatic squamous cell carcinoma of the head and neck in patients who previously failed platinum-based therapies

An anatomical study of anastomoses between the laryngeal nerves.

A retrospective analysis of the outcome of patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck refractory to a platinum-based chemotherapy

Influence of the persistence of tobacco and alcohol use in the appearance of second neoplasm in patients with a head and neck cancer. A case-control study

Variability in nerve patterns of the adductor muscle group supplied by the recurrent laryngeal nerve.

Pretreatment count of peripheral neutrophils, monocytes, and lymphocytes as independent prognostic factor in patients with head and neck cancer

Selective dissection of levels II-III with intraoperative control of the upper and middle jugular nodes: A therapeutic option for the no neck

Salvage surgery after locoregional failure in head and neck carcinoma patients treated with chemoradiotherapy.

uPA/uPAR and SERPINE1 in head and neck cancer: role in tumor resistance, metastasis, prognosis and therapy

Prostaglandin E(2) pathway in head and neck squamous cell carcinoma

Interaction between head and neck squamous cell carcinoma cells and fibroblasts in the biosynthesis of PGE2.

Enhanced cell migration and apoptosis resistance may underlie the association between high SERPINE1 expression and poor outcome in head and neck carcinoma patients.

Tumor cells induce COX-2 and mPGES-1 expression in microvascular endothelial cells mainly by means of IL-1 receptor activation.

Metachronous second primary tumours in the aerodigestive tract in patients with early stage head and neck squamous cell carcinomas

Ku70 predicts response and primary tumor recurrence after therapy in locally advanced head and neck cancer.

Variability of the nerve supply patterns of the human posterior cricoarytenoid muscle.

Gene expression signatures and molecular markers associated with clinical outcome in locally advanced head and neck carcinoma.

The effect of waiting time on local control and survival in head and neck carcinoma patients treated with radiotherapy

Classification of parotidectomies: a proposal of the European Salivary Gland Society

Incidence and significance of clinically unsuspected thyroid tissue in lymph nodes found during neck dissection in head and neck carcinoma patients

Human papillomavirus as prognostic marker with rising prevalence in neck squamous cell carcinoma of unknown primary: A retrospective multicentre study.

Supracricoid laryngectomy as salvage surgery after failure of radiation therapy

Prognostic role of MMP-9 expression in head and neck carcinoma patients treated with radiotherapy or chemoradiotherapy

Expression of IL-1α correlates with distant metastasis in patients with head and neck squamous cell carcinoma

Second, third, and fourth head and neck tumors. A progressive decrease in survival

Potential structures that could be confused with a nonrecurrent inferior laryngeal nerve: an anatomic study

The role of HPV on the risk of second primary neoplasia in patients with oropharyngeal carcinoma

Laryngeal cancer in non-smoking and non-drinking patients

Prostacyclin-synthase expression in head and neck carcinoma patients and its prognostic value in the response to radiotherapy

Parotidectomies in benign parotid tumours: "Sant Pau" surgical extension classification

Management of recurrent head and neck cancer: variables related to salvage surgery

High RAB25 expression is associated with good clinical outcome in patients with locally advanced head and neck squamous cell carcinoma

Overexpression of the nuclear factor-kappa B (p65) in association with local failure in patients with head and neck carcinoma undergong radiotherapy or chemoradiotherapy

Prognostic factors in head and neck squamous cell carcinoma: Comparison of CHAID decision trees technology and cox analysis

Results of an organ preservation protocol with induction chemotherapy and radiotherapy in patients with locally advanced laryngeal carcinoma

Total or subtotal glossectomy with microsurgical reconstruction: functional and oncological results

Comparison of the Radiation Therapy Oncology Group recursive partitioning classification and Union Internationale Contre le Cancer TNM classification for patients with head and neck carcinoma

Salvage surgery after local recurrence in patients with head and neck carcinoma treated with chemoradiotherapy or bioradiotherapy

CKMT1 and NCOA1 expression as a predictor of clinical outcome in patients with advanced-stage head and neck squamous cell carcinoma.

External validation of sTWEAK as a prognostic noninvasive biomarker for head and neck squamous cell carcinoma.

Low blood levels of sTWEAK are related to locoregional failure in head and neck cancer.

Validation of the pathological classification of lymph node metastasis for head and neck tumors according to the 8th edition of the TNM Classification of Malignant Tumors.

Foramen thyroideum: a comparative study in embryos, fetuses, and adults

Delayed carotid blow-out syndrome: a new complication of chemoradiotherapy treatment in pharyngolaryngeal carcinoma

External validation of a risk group defined by recursive partitioning analysis in patients with head and neck carcinoma treated with surgery and postoperative radiotherapy

The prognostic value of pretreatment platelet count in patients with head and neck squamous cell carcinoma

Competing mortality in oropharyngeal carcinoma according to human papillomavirus status

Expression of the CXCL12/CXCR4 chemokine axis predicts regional control in head and neck squamous cell carcinoma.

The combined use of EFS, GPX2, and SPRR1A expression could distinguish favorable from poor clinical outcome among epithelial-like head and neck carcinoma subtypes