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List of works by Sirpa Leppä

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Rituximab maintenance for 2 years in patients with high tumour burden follicular lymphoma responding to rituximab plus chemotherapy (PRIMA): a phase 3, randomised controlled trial.

scientific article
Genetic and Functional Drivers of Diffuse Large B Cell Lymphoma

scientific article
Activating mutations of STAT5B and STAT3 in lymphomas derived from γδ-T or NK cells

scientific article published on 14 January 2015
A high tumor-associated macrophage content predicts favorable outcome in follicular lymphoma patients treated with rituximab and cyclophosphamide-doxorubicin-vincristine-prednisone.

scientific article published in October 2007
EGF-R regulates MMP function in fibroblasts through MAPK and AP-1 pathways.

scientific article
Phosphatidylinositol 3-Kinase Inhibition by Copanlisib in Relapsed or Refractory Indolent Lymphoma

scientific article published on 4 October 2017
Risk Factors and Outcomes for Patients With Follicular Lymphoma Who Had Histologic Transformation After Response to First-Line Immunochemotherapy in the PRIMA Trial.

scientific article published on 13 June 2016
FGF21 is a biomarker for mitochondrial translation and mtDNA maintenance disorders

scientific article published on 28 October 2016
Randomized, Double-Blind, Phase III Trial of Enzastaurin Versus Placebo in Patients Achieving Remission After First-Line Therapy for High-Risk Diffuse Large B-Cell Lymphoma

scientific article published on 23 May 2016
Male gender is an adverse prognostic factor in B-cell lymphoma patients treated with immunochemotherapy.

scientific article published on 22 December 2010
Ofatumumab Versus Rituximab Salvage Chemoimmunotherapy in Relapsed or Refractory Diffuse Large B-Cell Lymphoma: The ORCHARRD Study.

scientific article published on 28 December 2016
Autologous stem cell transplantation in adult patients with peripheral T-cell lymphoma: a nation-wide survey.

scientific article published on February 2004
Mitogen-activated Protein Kinases and Activator Protein 1 Are Required for Proliferation and Cardiomyocyte Differentiation of P19 Embryonal Carcinoma Cells

scientific article published on 07 March 2002
Prognostic influence of macrophages in patients with diffuse large B-cell lymphoma: a correlative study from a Nordic phase II trial

scientific article published on 7 November 2014
Autologous stem cell transplantation in elderly (>60 years) patients with non-Hodgkin's lymphoma: a nation-wide analysis.

scientific article published in February 2006
Prognostic influence of tumor-infiltrating mast cells in patients with follicular lymphoma treated with rituximab and CHOP.

scientific article
Mitogen activated protein kinase-dependent activation of c-Jun and c-Fos is required for neuronal differentiation but not for growth and stress response in PC12 cells

scientific article published on 01 February 2007
Transcription factor AP-1 promotes growth and radioresistance in prostate cancer cells

scientific article published on November 2009
Randomized Phase III Trial of Ibrutinib and Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Non-Germinal Center B-Cell Diffuse Large B-Cell Lymphoma.

scientific article
The Hans algorithm is not prognostic in patients with diffuse large B-cell lymphoma treated with R-CHOP.

scientific article published on 24 January 2012
Successful change of treatment strategy in elderly patients with primary central nervous system lymphoma by de-escalating induction and introducing temozolomide maintenance: results from a phase II study by the Nordic Lymphoma Group

scientific article
Bcl-2 but not FOXP1, is an adverse risk factor in immunochemotherapy-treated non-germinal center diffuse large B-cell lymphomas.

scientific article published on 9 January 2009
Enteropathy-associated T cell lymphoma subtypes are characterized by loss of function of SETD2.

scientific article
Early treatment-related mortality in adult autologous stem cell transplant recipients: a nation-wide survey of 1482 transplanted patients.

scientific article published on 12 January 2006
Differential gene expression in non-malignant tumour microenvironment is associated with outcome in follicular lymphoma patients treated with rituximab and CHOP.

scientific article published on 22 August 2006
Late non-relapse mortality among adult autologous stem cell transplant recipients: a nation-wide analysis of 1482 patients transplanted in 1990–2003

scientific article published on 01 August 2006
Prognostic impact of protein kinase C β II expression in R-CHOP-treated diffuse large B-cell lymphoma patients

scientific article published on February 26, 2010
Combining MYC, BCL2 and TP53 gene and protein expression alterations improves risk stratification in diffuse large B-cell lymphoma

article
Impact of germinal center and non-germinal center phenotypes on overall and failure-free survival after high-dose chemotherapy and auto-SCT in primary diffuse large B-cell lymphoma.

scientific article published on 7 April 2008
Deregulation of COMMD1 is associated with poor prognosis in diffuse large B-cell lymphoma

scientific article
E6/E7 oncogenes increase and tumor suppressors decrease the proportion of self-renewing neural progenitor cells

scientific article published on 13 March 2006
Sustained Progression-Free Survival Benefit of Rituximab Maintenance in Patients With Follicular Lymphoma: Long-Term Results of the PRIMA Study

scientific article published on 24 July 2019
(18)F-fluorodeoxyglucose-positron emission tomography/computed tomography after one cycle of chemotherapy in patients with diffuse large B-cell lymphoma: results of a Nordic/US intergroup study.

scientific article published on 20 November 2014
Rituximab regulates signaling pathways and alters gene expression associated with cell death and survival in diffuse large B-cell lymphoma

scientific article published on 10 February 2011
PD-L1 tumor-associated macrophages and PD-1 tumor-infiltrating lymphocytes predict survival in primary testicular lymphoma

scholarly article by Marjukka Pollari et al published November 2018 in Haematologica
Prognostic impact of CD31-positive microvessel density in follicular lymphoma patients treated with immunochemotherapy.

scientific article published on 12 July 2010
High serum vascular endothelial growth factor level is an adverse prognostic factor for high‐risk diffuse large B‐cell lymphoma patients treated with dose‐dense chemoimmunotherapy

scientific article published on September 14, 2012
Primary mediastinal large B-cell lymphoma segregating in a family: exome sequencing identifies MLL as a candidate predisposition gene

scientific article
CD40 is a potential marker of favorable prognosis in patients with diffuse large B-cell lymphoma treated with immunochemotherapy.

scientific article published in September 2010
Hydrocortisone and indomethacin negatively modulate EGF-R signaling in human fetal intestine

scientific article published on November 2007
Rituximab maintenance obviates the poor prognosis associated with circulating lymphoma cells in patients with follicular lymphoma

scientific article published on 01 April 2014
Deltex-1 mutations predict poor survival in diffuse large B-cell lymphoma

scientific article published on 9 February 2017
Effect of treatment of larynx and hypopharynx carcinomas on serum syndecan-1 concentrations

scientific article published on 24 March 2006
Alternative splicing discriminates molecular subtypes and has prognostic impact in diffuse large B-cell lymphoma.

scientific article published on 25 August 2017
Identification of homozygous deletion inACANand other candidate variants in familial classical Hodgkin lymphoma by exome sequencing

scientific article published on 25 February 2015
MicroRNAs regulate key cell survival pathways and mediate chemosensitivity during progression of diffuse large B-cell lymphoma.

scientific article
Constant pattern of relapse in primary central nervous lymphoma patients treated with high-dose methotrexate combinations. A Finnish retrospective study

scientific article
Similar outcomes in Asian and Western patients with diffuse large B-cell lymphoma treated with R-CHOP.

scientific article published on 24 January 2013
Signal transducers and activators of transcription 5a-dependent cross-talk between follicular lymphoma cells and tumor microenvironment characterizes a group of patients with improved outcome after R-CHOP.

scientific article published on 13 April 2010
Up-front rituximab maintenance improves outcome in patients with follicular lymphoma: a collaborative Nordic study

scientific article published on 01 July 2018

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