List of works - Kathleen J Millen

Consensus paper: pathological role of the cerebellum in autism

scientific article

The mouse Dreher gene Lmx1a controls formation of the roof plate in the vertebrate CNS.

scientific article published in February 2000

Functional analysis of the weaver mutant GIRK2 K+ channel and rescue of weaver granule cells

scientific article published on May 1996

Tissue-specific thyroid hormone deprivation and excess in monocarboxylate transporter (mct) 8-deficient mice

scientific article published on 18 May 2006

Active medulloblastoma enhancers reveal subgroup-specific cellular origins

scientific article published on 27 January 2016

Cilia Proteins Control Cerebellar Morphogenesis by Promoting Expansion of the Granule Progenitor Pool

scientific article published on 01 September 2007

Heterozygous deletion of the linked genes ZIC1 and ZIC4 is involved in Dandy-Walker malformation

scientific article

Roof plate-dependent patterning of the vertebrate dorsal central nervous system

scientific article

FOXC1 is required for normal cerebellar development and is a major contributor to chromosome 6p25.3 Dandy-Walker malformation

scientific journal article

A developmental and genetic classification for midbrain-hindbrain malformations

scientific article published on December 2009

The roof plate regulates cerebellar cell-type specification and proliferation

scientific article published on 21 June 2006

Cerebellar development and disease

scientific article

Proprioceptive sensory neuropathy in mice with a mutation in the cytoplasmic Dynein heavy chain 1 gene

scientific article

The ZIC gene family in development and disease.

scientific article

Consensus Paper: Cerebellar Development.

scientific article published on 6 October 2015

Lmx1a is required for segregation of sensory epithelia and normal ear histogenesis and morphogenesis

scientific article

Abnormal embryonic cerebellar development and patterning of postnatal foliation in two mouse Engrailed-2 mutants.

scientific article

Mapping of deletion and translocation breakpoints in 1q44 implicates the serine/threonine kinase AKT3 in postnatal microcephaly and agenesis of the corpus callosum

scientific article

The transcription factor encyclopedia

scientific article (publication date: 2012)

Lmx1a regulates fates and location of cells originating from the cerebellar rhombic lip and telencephalic cortical hem

scientific article

Development and malformations of the cerebellum in mice

scientific article published on September 2003

A role for En-2 and other murine homologues of Drosophila segment polarity genes in regulating positional information in the developing cerebellum

scientific journal article

Genetic variation and population substructure in outbred CD-1 mice: implications for genome-wide association studies

scientific article (publication date: 2009)

Loss of cyclin D1 impairs cerebellar development and suppresses medulloblastoma formation

scientific article published on 30 August 2006

Control of roof plate formation by Lmx1a in the developing spinal cord

scientific journal article

Examining pattern formation in mouse, chicken and frog embryos with an En-specific antiserum

scientific article published in February 1991

Multiple developmental programs are altered by loss of Zic1 and Zic4 to cause Dandy-Walker malformation cerebellar pathogenesis

scientific article

Control of roof plate development and signaling by Lmx1b in the caudal vertebrate CNS.

scientific article

Impaired motor learning performance in cerebellar En-2 mutant mice

scientific article published in February 1996

Mechanisms of roof plate formation in the vertebrate CNS.

scientific article published in October 2004

Lmx1a maintains proper neurogenic, sensory, and non-sensory domains in the mammalian inner ear.

scientific article

Rhombencephalosynapsis: a hindbrain malformation associated with incomplete separation of midbrain and forebrain, hydrocephalus and a broad spectrum of severity

scientific article published on 26 March 2012

Zic1 and Zic4 regulate zebrafish roof plate specification and hindbrain ventricle morphogenesis

scientific article published on 15 December 2007

Cerebellar and posterior fossa malformations in patients with autism-associated chromosome 22q13 terminal deletion

scientific article

Mutation of FOXC1 and PITX2 induces cerebral small-vessel disease

scientific article

A developmental classification of malformations of the brainstem

scientific article

Differential gene expression in the developing lateral geniculate nucleus and medial geniculate nucleus reveals novel roles for Zic4 and Foxp2 in visual and auditory pathway development

scientific article

Midbrain and hindbrain malformations: advances in clinical diagnosis, imaging, and genetics.

scientific article published on 18 March 2013

Both rare and de novo copy number variants are prevalent in agenesis of the corpus callosum but not in cerebellar hypoplasia or polymicrogyria

scientific article

Roof plate and dorsal spinal cord dl1 interneuron development in the dreher mutant mouse

scientific journal article

Neurogenetics of the cerebellar system.

scientific article

DNA-protein interactions in the Caenorhabditis elegans embryo: oocyte and embryonic factors that bind to the promoter of the gut-specific ges-1 gene.

scientific article published on June 1994

Overlapping function of Lmx1a and Lmx1b in anterior hindbrain roof plate formation and cerebellar growth

scientific article

Transformation of the cerebellum into more ventral brainstem fates causes cerebellar agenesis in the absence of Ptf1a function

scientific article

Zac1 plays a key role in the development of specific neuronal subsets in the mouse cerebellum.

scientific article published on 18 May 2011

Mouse models of human PIK3CA-related brain overgrowth have acutely treatable epilepsy

scientific article published on 3 December 2015

Molecular definition of an allelic series of mutations disrupting the mouse Lmx1a (dreher) gene

scientific article published on 3 October 2006

Foxc1 dependent mesenchymal signalling drives embryonic cerebellar growth

scientific article

Reciprocal fusion transcripts of two novel Zn-finger genes in a female with absence of the corpus callosum, ocular colobomas and a balanced translocation between chromosomes 2p24 and 9q32.

scientific article published in July 2003

Mutations in CRADD Result in Reduced Caspase-2-Mediated Neuronal Apoptosis and Cause Megalencephaly with a Rare Lissencephaly Variant

scientific article published on 18 October 2016

List of works by Kathleen J Millen

Consensus paper: pathological role of the cerebellum in autism

The mouse Dreher gene Lmx1a controls formation of the roof plate in the vertebrate CNS.

Functional analysis of the weaver mutant GIRK2 K+ channel and rescue of weaver granule cells

Tissue-specific thyroid hormone deprivation and excess in monocarboxylate transporter (mct) 8-deficient mice

Active medulloblastoma enhancers reveal subgroup-specific cellular origins

Cilia Proteins Control Cerebellar Morphogenesis by Promoting Expansion of the Granule Progenitor Pool

Heterozygous deletion of the linked genes ZIC1 and ZIC4 is involved in Dandy-Walker malformation

Roof plate-dependent patterning of the vertebrate dorsal central nervous system

FOXC1 is required for normal cerebellar development and is a major contributor to chromosome 6p25.3 Dandy-Walker malformation

A developmental and genetic classification for midbrain-hindbrain malformations

The roof plate regulates cerebellar cell-type specification and proliferation

Cerebellar development and disease

Proprioceptive sensory neuropathy in mice with a mutation in the cytoplasmic Dynein heavy chain 1 gene

The ZIC gene family in development and disease.

Consensus Paper: Cerebellar Development.

Lmx1a is required for segregation of sensory epithelia and normal ear histogenesis and morphogenesis

Abnormal embryonic cerebellar development and patterning of postnatal foliation in two mouse Engrailed-2 mutants.

Mapping of deletion and translocation breakpoints in 1q44 implicates the serine/threonine kinase AKT3 in postnatal microcephaly and agenesis of the corpus callosum

The transcription factor encyclopedia

Lmx1a regulates fates and location of cells originating from the cerebellar rhombic lip and telencephalic cortical hem

Development and malformations of the cerebellum in mice

A role for En-2 and other murine homologues of Drosophila segment polarity genes in regulating positional information in the developing cerebellum

Genetic variation and population substructure in outbred CD-1 mice: implications for genome-wide association studies

Loss of cyclin D1 impairs cerebellar development and suppresses medulloblastoma formation

Control of roof plate formation by Lmx1a in the developing spinal cord

Examining pattern formation in mouse, chicken and frog embryos with an En-specific antiserum

Multiple developmental programs are altered by loss of Zic1 and Zic4 to cause Dandy-Walker malformation cerebellar pathogenesis

Control of roof plate development and signaling by Lmx1b in the caudal vertebrate CNS.

Impaired motor learning performance in cerebellar En-2 mutant mice

Mechanisms of roof plate formation in the vertebrate CNS.

Lmx1a maintains proper neurogenic, sensory, and non-sensory domains in the mammalian inner ear.

Rhombencephalosynapsis: a hindbrain malformation associated with incomplete separation of midbrain and forebrain, hydrocephalus and a broad spectrum of severity

Zic1 and Zic4 regulate zebrafish roof plate specification and hindbrain ventricle morphogenesis

Cerebellar and posterior fossa malformations in patients with autism-associated chromosome 22q13 terminal deletion

Mutation of FOXC1 and PITX2 induces cerebral small-vessel disease

A developmental classification of malformations of the brainstem

Differential gene expression in the developing lateral geniculate nucleus and medial geniculate nucleus reveals novel roles for Zic4 and Foxp2 in visual and auditory pathway development

Midbrain and hindbrain malformations: advances in clinical diagnosis, imaging, and genetics.

Both rare and de novo copy number variants are prevalent in agenesis of the corpus callosum but not in cerebellar hypoplasia or polymicrogyria

Roof plate and dorsal spinal cord dl1 interneuron development in the dreher mutant mouse

Neurogenetics of the cerebellar system.

DNA-protein interactions in the Caenorhabditis elegans embryo: oocyte and embryonic factors that bind to the promoter of the gut-specific ges-1 gene.

Overlapping function of Lmx1a and Lmx1b in anterior hindbrain roof plate formation and cerebellar growth

Transformation of the cerebellum into more ventral brainstem fates causes cerebellar agenesis in the absence of Ptf1a function

Zac1 plays a key role in the development of specific neuronal subsets in the mouse cerebellum.

Mouse models of human PIK3CA-related brain overgrowth have acutely treatable epilepsy

Molecular definition of an allelic series of mutations disrupting the mouse Lmx1a (dreher) gene

Foxc1 dependent mesenchymal signalling drives embryonic cerebellar growth

Reciprocal fusion transcripts of two novel Zn-finger genes in a female with absence of the corpus callosum, ocular colobomas and a balanced translocation between chromosomes 2p24 and 9q32.

Mutations in CRADD Result in Reduced Caspase-2-Mediated Neuronal Apoptosis and Cause Megalencephaly with a Rare Lissencephaly Variant