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List of works by Antonello Mai

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TNF/p38α/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration.

scientific article
BLUEPRINT to decode the epigenetic signature written in blood

scientific article
HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment

scholarly article
Histone deacetylation in epigenetics: an attractive target for anticancer therapy

scientific article
Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect.

scientific article
Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2

scientific article
Targeting Histone Demethylases: A New Avenue for the Fight against Cancer

scientific article published on June 1, 2011
Inhibition of class I histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue

scientific article published on 15 October 2012
HDAC4-regulated STAT1 activation mediates platinum resistance in ovarian cancer.

scientific article
"Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence

scientific article
Class II (IIa)-selective histone deacetylase inhibitors. 1. Synthesis and biological evaluation of novel (aryloxopropenyl)pyrrolyl hydroxyamides

scientific article published in May 2005
Epi-drugs to fight cancer: from chemistry to cancer treatment, the road ahead

scientific article published on 22 August 2008
Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity of HDAC-MEF2 complexes

scientific article
Oxidative stress and epigenetic regulation in ageing and age-related diseases

scientific article
Inhibition of Histone Deacetylase Class I but not Class II Is Critical for the Sensitization of Leukemic Cells to Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Induced Apoptosis

article by Satoshi Inoue et al published 1 July 2006 in Cancer Research
Design, synthesis, and biological evaluation of sirtinol analogues as class III histone/protein deacetylase (Sirtuin) inhibitors

scientific article
SIRT5 regulation of ammonia-induced autophagy and mitophagy

scientific article published in January 2015
epigenetic multiple ligands: mixed histone/protein methyltransferase, acetyltransferase, and class III deacetylase (sirtuin) inhibitors.

scientific article
Nε-lysine acetylation determines dissociation from GAP junctions and lateralization of connexin 43 in normal and dystrophic heart

scientific article
Specific control of pancreatic endocrine β- and δ-cell mass by class IIa histone deacetylases HDAC4, HDAC5, and HDAC9

scientific article
Specific activity of class II histone deacetylases in human breast cancer cells

scientific article
Sirtuin functions and modulation: from chemistry to the clinic

scientific article
Small molecule inhibitors of histone arginine methyltransferases: homology modeling, molecular docking, binding mode analysis, and biological evaluations

scientific article published on 27 February 2007
p300/CBP-associated factor selectively regulates the extinction of conditioned fear

scientific article
Small-molecule inhibitors of histone acetyltransferase activity: identification and biological properties

scientific article published on November 2006
Histone deacetylase-3 activation promotes tumor necrosis factor-alpha (TNF-alpha) expression in cardiomyocytes during lipopolysaccharide stimulation

scientific article
Nitric oxide modulates chromatin folding in human endothelial cells via protein phosphatase 2A activation and class II histone deacetylases nuclear shuttling

scientific article published on 01 November 2007
Gold drug auranofin restricts the viral reservoir in the monkey AIDS model and induces containment of viral load following ART suspension

scientific article published in July 2011
Histone deacetylase inhibitors and neurodegenerative disorders: holding the promise

scientific article published on January 2009
Histone deacetylase inhibitors induce thyroid cancer-specific apoptosis through proteasome-dependent inhibition of TRAIL degradation.

scientific article published on 5 October 2009
Study of 1,4-dihydropyridine structural scaffold: discovery of novel sirtuin activators and inhibitors

scientific article
Histone acetyltransferase inhibitors and preclinical studies

scientific article published on June 2009
Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities.

scientific article
Epi-drugs in combination with immunotherapy: a new avenue to improve anticancer efficacy

scientific article published on 30 May 2017
The Polycomb group (PcG) protein EZH2 supports the survival of PAX3-FOXO1 alveolar rhabdomyosarcoma by repressing FBXO32 (Atrogin1/MAFbx).

scientific article published on 11 November 2013
Dihydro(alkylthio)(naphthylmethyl)oxopyrimidines: novel non-nucleoside reverse transcriptase inhibitors of the S-DABO series

scientific article published on May 1997
HDAC-class II specific inhibition involves HDAC proteasome-dependent degradation mediated by RANBP2.

scientific article
Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors

scientific article published on 4 January 2018
HDACs class II-selective inhibition alters nuclear receptor-dependent differentiation

scientific article published on 16 July 2010
The histone deacetylase inhibitor suberoylanilide hydroxamic acid reduces cardiac arrhythmias in dystrophic mice

scientific article published on 17 February 2010
Role of endogenous reverse transcriptase in murine early embryo development

scientific article published in November 2003
Identification of long chain alkylidenemalonates as novel small molecule modulators of histone acetyltransferases.

scientific article published on 11 April 2008
Novel 3,5-bis(bromohydroxybenzylidene)piperidin-4-ones as coactivator-associated arginine methyltransferase 1 inhibitors: enzyme selectivity and cellular activity

scientific article published on 13 June 2011
An Analog of BIX-01294 Selectively Inhibits a Family of Histone H3 Lysine 9 Jumonji Demethylases

scientific article
5-Alkyl-2-(alkylthio)-6-(2,6-dihalophenylmethyl)-3, 4-dihydropyrimidin-4(3H)-ones: novel potent and selective dihydro-alkoxy-benzyl-oxopyrimidine derivatives

scientific article
Interplay among nucleosomal DNA, histone tails, and corepressor CoREST underlies LSD1-mediated H3 demethylation

scientific article
Synthesis and biological validation of novel synthetic histone/protein methyltransferase inhibitors

scientific article published on July 2007
The therapeutic uses of chromatin-modifying agents

scientific article published on June 2007
A photoreactive small-molecule probe for 2-oxoglutarate oxygenases

scientific article
Class II HDAC inhibition hampers hepatic stellate cell activation by induction of microRNA-29

scientific article

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