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List of works by Matthew J. Sweet

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HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi

scientific article published on 23 July 2015
Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages

scientific article published on 2 February 2016
Differences in the repertoire, regulation and function of Toll-like Receptors and inflammasome-forming Nod-like Receptors between human and mouse.

scientific article published on 26 March 2013
Uropathogenic Escherichia coli Engages CD14-Dependent Signaling to Enable Bladder-Macrophage-Dependent Control of Acute Urinary Tract Infection.

scientific article published on 30 August 2015
Innate immune perturbations, accumulating DAMPs and inflammasome dysregulation: A ticking time bomb in ageing

scientific article published on 25 February 2015
Portal, but not lobular, macrophages express matrix metalloproteinase-9: association with the ductular reaction and fibrosis in chronic hepatitis C

scientific article published on 13 December 2012
Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4

article
Histone Deacetylase Inhibitors Promote Mitochondrial Reactive Oxygen Species Production and Bacterial Clearance by Human Macrophages.

scientific article published on 28 December 2015
An mRNA atlas of G protein-coupled receptor expression during primary human monocyte/macrophage differentiation and lipopolysaccharide-mediated activation identifies targetable candidate regulators of inflammation.

scientific article
Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration

scientific article
Macrophage secretory products induce an inflammatory phenotype in hepatocytes

scientific article published in April 2012
TRIF-dependent TLR signaling, its functions in host defense and inflammation, and its potential as a therapeutic target

scientific article published on 9 May 2016
Interferon regulatory factor 6 differentially regulates Toll-like receptor 2-dependent chemokine gene expression in epithelial cells.

scientific article
Towards isozyme-selective HDAC inhibitors for interrogating disease.

scientific article published on January 2012
The role of H4 flagella in Escherichia coli ST131 virulence

scientific article
Experimental and bioinformatic characterisation of the promoter region of the Marfan syndrome gene, FBN1.

scientific article
The mammalian DUF59 protein Fam96a forms two distinct types of domain-swapped dimer

scientific article published on 17 May 2012
Tumor cell-expressed SerpinB2 is present on microparticles and inhibits metastasis

scientific article
Small GTPase Rab8a-recruited Phosphatidylinositol 3-Kinase γ Regulates Signaling and Cytokine Outputs from Endosomal Toll-like Receptors.

scientific article published on 27 January 2017
Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury

scientific article
Genome-Wide Discovery of Genes Required for Capsule Production by Uropathogenic Escherichia coli

scientific article published on 24 October 2017
The cytochrome bd-I respiratory oxidase augments survival of multidrug-resistant Escherichia coli during infection.

scientific article published on 21 October 2016
Differential Anti-inflammatory Activity of HDAC Inhibitors in Human Macrophages and Rat Arthritis

scientific article published on 10 December 2015
B cells do not take up bacterial DNA: an essential role for antigen in exposure of DNA to toll-like receptor-9.

scientific article published on 5 October 2010
Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists.

scientific article
Using the MCoTI-II Cyclotide Scaffold To Design a Stable Cyclic Peptide Antagonist of SET, a Protein Overexpressed in Human Cancer

scientific article published on 21 December 2015
For when bacterial infections persist: Toll-like receptor-inducible direct antimicrobial pathways in macrophages.

scientific article published on 3 January 2018
Hyaluronan synthase 2-mediated hyaluronan production mediates Notch1 activation and liver fibrosis

scientific article published on 01 June 2019
A conserved distal segment of the mouse CSF-1 receptor promoter is required for maximal expression of a reporter gene in macrophages and osteoclasts of transgenic mice

article
The toll-like receptor 3 pathway in homeostasis, responses to injury and wound repair.

scientific article published on 20 August 2016
TLR9-independent effects of inhibitory oligonucleotides on macrophage responses to S. typhimurium

scientific article
SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophages

scientific article published on 18 January 2017
Inhibitors selective for HDAC6 in enzymes and cells

scientific article published on October 12, 2010
An HDAC6 Inhibitor Confers Protection and Selectively Inhibits B-Cell Infiltration in DSS-Induced Colitis in Mice.

scientific article published on 8 November 2016
Group A streptococcal pharyngitis: immune responses involved in bacterial clearance and GAS-associated immunopathologies

scientific article published on 26 September 2017
The immunostimulatory activity of phosphorothioate CpG oligonucleotides is affected by distal sequence changes

scientific article published on 16 February 2011
Development and characterization of new inhibitors of the human and mouse hematopoietic prostaglandin D(2) synthases.

scientific article published on August 2010
Regulation of the endosomal SNARE protein syntaxin 7 by colony-stimulating factor 1 in macrophages

scientific article published on 18 August 2008
Towards selective lysophospholipid GPCR modulators

scientific article
Analysis of the N-terminal region of human MLKL, as well as two distinct MLKL isoforms, reveals new insights into necroptotic cell death

scientific article
The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidized

scientific article
The murine neutrophil NLRP3 inflammasome is activated by soluble but not particulate or crystalline agonists

scientific article published on February 2016
Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival

scientific article published on 26 September 2009
Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophages.

scientific article
Uropathogenic employs both evasion and resistance to subvert innate immune-mediated zinc toxicity for dissemination

article
HDACs and their inhibitors in immunology: teaching anticancer drugs new tricks

scientific article published on 01 January 2012
Lysine Deacetylases and Regulated Glycolysis in Macrophages.

scientific article
Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes

article
The TLR signalling adaptor TRIF/TICAM-1 has an N-terminal helical domain with structural similarity to IFIT proteins

scientific article
The E3 ubiquitin ligase RNF144B is LPS-inducible in human, but not mouse, macrophages and promotes inducible IL-1β expression

scientific article published on 27 January 2016

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