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List of works by Mark W. Kieran

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The DNA binding subunit of NF-kappa B is identical to factor KBF1 and homologous to the rel oncogene product

scientific article (publication date: 7 September 1990)
Identification of fibroblast heterogeneity in the tumor microenvironment

scientific article published on 05 December 2006
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

scientific article
A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors.

scientific article published on 31 October 2003
Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition

scientific article
The cloche and spadetail Genes Differentially Affect Hematopoiesis and Vasculogenesis

scientific article published on May 15, 1998
Profiling critical cancer gene mutations in clinical tumor samples

scientific article
Neutralization of Circulating Vascular Endothelial Growth Factor (VEGF) by Anti-VEGF Antibodies and Soluble VEGF Receptor 1 (sFlt-1) Induces Proteinuria

scientific article published in Journal of Biological Chemistry
Myelopoiesis in the zebrafish, Danio rerio.

scientific article published in August 2001
In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight

scientific article
BET bromodomain inhibition of MYC-amplified medulloblastoma.

scientific article published on 2 December 2013
Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma

scientific article
Intensive Multimodality Treatment for Children With Newly Diagnosed CNS Atypical Teratoid Rhabdoid Tumor

scientific article (publication date: 20 January 2009)
PPARalpha agonist fenofibrate suppresses tumor growth through direct and indirect angiogenesis inhibition.

scholarly article
Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas

scientific article
Clinical trial of a farnesyltransferase inhibitor in children with Hutchinson-Gilford progeria syndrome

scientific article
Platelets actively sequester angiogenesis regulators

scientific article
Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice

scientific article published on 19 December 2011
Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis

scientific article published on 3 April 2013
Contribution of bone microenvironment to leukemogenesis and leukemia progression

scientific article
Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1

scientific article published on 30 April 2013
Phase I trial of imatinib in children with newly diagnosed brainstem and recurrent malignant gliomas: a Pediatric Brain Tumor Consortium report

scientific article published on 9 February 2007
Phase I clinical trial of cilengitide in children with refractory brain tumors: Pediatric Brain Tumor Consortium Study PBTC-012.

scientific article
Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq

scientific article published in April 2018
Impact of farnesylation inhibitors on survival in Hutchinson-Gilford progeria syndrome.

scientific article
MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism

scientific article
A feasibility trial of antiangiogenic (metronomic) chemotherapy in pediatric patients with recurrent or progressive cancer

scientific article
The VEGF pathway in cancer and disease: responses, resistance, and the path forward.

scientific article published on December 2012
NF1 plexiform neurofibroma growth rate by volumetric MRI: relationship to age and body weight.

scientific article published on 10 January 2007
Thrombospondin-1 associated with tumor microenvironment contributes to low-dose cyclophosphamide-mediated endothelial cell apoptosis and tumor growth suppression

scientific article published on March 2004
Moyamoya following cranial irradiation for primary brain tumors in children.

scientific article published in March 2007
Function of endogenous inhibitors of angiogenesis as endothelium-specific tumor suppressors

scientific article
Epoxyeicosanoids promote organ and tissue regeneration.

scientific article published on 29 July 2013
Biology of childhood osteogenic sarcoma and potential targets for therapeutic development: meeting summary.

scientific article published on November 2003
PPARgamma as a therapeutic target for tumor angiogenesis and metastasis

scientific article
Phase II trial of temsirolimus in children with high-grade glioma, neuroblastoma and rhabdomyosarcoma

scientific article
Long-term outcome of 4,040 children diagnosed with pediatric low-grade gliomas: an analysis of the Surveillance Epidemiology and End Results (SEER) database

scientific article
Disease progression in Hutchinson-Gilford progeria syndrome: impact on growth and development

scientific article published in October 2007
Anti-apoptosis mechanisms in malignant gliomas.

scientific article published on January 2008
Efficacy of the HSP90 inhibitor 17-AAG in human glioma cell lines and tumorigenic glioma stem cells

scientific article
Phase II study of metronomic chemotherapy for recurrent malignant gliomas in adults.

scientific article
Pediatric high-grade glioma: biologically and clinically in need of new thinking

scientific article
Critical oncogenic mutations in newly diagnosed pediatric diffuse intrinsic pontine glioma

scientific article published on 20 December 2011
New approaches to progeria

scientific article published on October 2007
A phase II trial of a multi-agent oral antiangiogenic (metronomic) regimen in children with recurrent or progressive cancer.

scientific article
PPARalpha deficiency in inflammatory cells suppresses tumor growth

scientific article published on 28 February 2007
Mechanisms of premature vascular aging in children with Hutchinson-Gilford progeria syndrome

scientific article published on 14 November 2011
Phase II study of temozolomide, thalidomide, and celecoxib for newly diagnosed glioblastoma in adults

scientific article
Clinical Trial of the Protein Farnesylation Inhibitors Lonafarnib, Pravastatin, and Zoledronic Acid in Children With Hutchinson-Gilford Progeria Syndrome

scientific article published on July 2016
Proceedings from the 2009 genetic syndromes of the Ras/MAPK pathway: From bedside to bench and back

scientific article published in January 2010

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