List of works - Nicholas P. Tatonetti

Data-driven prediction of drug effects and interactions

scientific article

Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis

scientific article

Detecting drug interactions from adverse-event reports: interaction between paroxetine and pravastatin increases blood glucose levels.

scientific article published on 25 May 2011

Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study

scientific article published on 05 June 2013

Web-scale pharmacovigilance: listening to signals from the crowd

scientific article

A novel signal detection algorithm for identifying hidden drug-drug interactions in adverse event reports

scientific article published on 14 June 2011

High-throughput methods for combinatorial drug discovery

scientific article published on October 2013

Birth month affects lifetime disease risk: a phenome-wide method

scientific article

Toward a complete dataset of drug-drug interaction information from publicly available sources

scientific article (publication date: June 2015)

Similarity-based modeling in large-scale prediction of drug-drug interactions

scientific article

A curated and standardized adverse drug event resource to accelerate drug safety research

scientific article

Mapping the effects of drugs on the immune system

scientific article

The Weber effect and the United States Food and Drug Administration's Adverse Event Reporting System (FAERS): analysis of sixty-two drugs approved from 2006 to 2010.

scientific article published on April 2014

Detection of drug-drug interactions by modeling interaction profile fingerprints

scientific article

Bridging islands of information to establish an integrated knowledge base of drugs and health outcomes of interest

scientific article

Cooperative transcription factor associations discovered using regulatory variation

scientific article

Disease risk factors identified through shared genetic architecture and electronic medical records

scientific article

Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes

scientific article (publication date: 2013)

Connecting the Dots: Applications of Network Medicine in Pharmacology and Disease

scientific article published on August 29, 2013

Systems pharmacology augments drug safety surveillance

scientific article

Systems biology approaches for identifying adverse drug reactions and elucidating their underlying biological mechanisms

scientific article published on 12 November 2015

Stimulated reporting: the impact of US food and drug administration-issued alerts on the adverse event reporting system (FAERS)

scientific article

Coherent functional modules improve transcription factor target identification, cooperativity prediction, and disease association

scientific article

An integrative method for scoring candidate genes from association studies: application to warfarin dosing

scientific article published on 28 October 2010

Similarity-based modeling applied to signal detection in pharmacovigilance.

scientific article

STORMSeq: an open-source, user-friendly pipeline for processing personal genomics data in the cloud

scientific article

Novel (coumarin-3-yl)carbamates as selective MAO-B inhibitors: synthesis, in vitro and in vivo assays, theoretical evaluation of ADME properties and docking study

scientific article published on 16 February 2013

Development and validation of a classification approach for extracting severity automatically from electronic health records

scientific article

Immune complement and coagulation dysfunction in adverse outcomes of SARS-CoV-2 infection

scientific article published on 03 August 2020

Interpretome: a freely available, modular, and secure personal genome interpretation engine

scientific article published on January 2012

Synthesis, pharmacological study and docking calculations of new benzo[f]coumarin derivatives as dual inhibitors of enzymatic systems involved in neurodegenerative diseases

scientific article published on March 2014

An Integrative Data Science Pipeline to Identify Novel Drug Interactions that Prolong the QT Interval

scientific article

A Computational Drug Repositioning Approach for Targeting Oncogenic Transcription Factors

scientific article published on 31 May 2016

State of the Art and Development of a Drug-Drug Interaction Large Scale Predictor Based on 3D Pharmacophoric Similarity

scientific article published on January 1, 2014

Ten Simple Rules to Enable Multi-site Collaborations through Data Sharing

scientific article (publication date: 2017)

Pathway analysis of genome-wide data improves warfarin dose prediction

scientific article

Insight into the Functional and Structural Properties of 3-Arylcoumarin as an Interesting Scaffold in Monoamine Oxidase B Inhibition

scientific article published on 08 April 2014

Shotgun Transcriptome and Isothermal Profiling of SARS-CoV-2 Infection Reveals Unique Host Responses, Viral Diversification, and Drug Interactions

scientific article published on 20 April 2020

3D pharmacophoric similarity improves multi adverse drug event identification in pharmacovigilance

scientific article

Investigation of 7-dehydrocholesterol reductase pathway to elucidate off-target prenatal effects of pharmaceuticals: a systematic review

scientific article

Uncovering exposures responsible for birth season - disease effects: a global study

scientific article published on 28 September 2017

Columbia Open Health Data, clinical concept prevalence and co-occurrence from electronic health records

article

MAO Inhibitory Activity of 2-Arylbenzofurans versus 3-Arylcoumarins: Synthesis, in vitro Study, and Docking Calculations

scientific article published on 15 April 2013

Connectivity Homology Enables Inter-Species Network Models of Synthetic Lethality

scientific article (publication date: October 2015)

Improving Detection of Arrhythmia Drug-Drug Interactions in Pharmacovigilance Data through the Implementation of Similarity-Based Modeling

scientific article

A Pharmacovigilance Signaling System Based on FDA Regulatory Action and Post-Marketing Adverse Event Reports

article

Testing the association between blood type and COVID-19 infection, intubation, and death

scientific article published on 11 April 2020

VenomKB, a new knowledge base for facilitating the validation of putative venom therapies

scientific article published on November 24, 2015

Associations between blood type and COVID-19 infection, intubation, and death

scientific article published on 13 November 2020

Insight into the interactions between novel coumarin derivatives and human A3 adenosine receptors

scientific article

List of works by Nicholas P. Tatonetti

Data-driven prediction of drug effects and interactions

Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis

Detecting drug interactions from adverse-event reports: interaction between paroxetine and pravastatin increases blood glucose levels.

Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study

Web-scale pharmacovigilance: listening to signals from the crowd

A novel signal detection algorithm for identifying hidden drug-drug interactions in adverse event reports

High-throughput methods for combinatorial drug discovery

Birth month affects lifetime disease risk: a phenome-wide method

Toward a complete dataset of drug-drug interaction information from publicly available sources

Similarity-based modeling in large-scale prediction of drug-drug interactions

A curated and standardized adverse drug event resource to accelerate drug safety research

Mapping the effects of drugs on the immune system

The Weber effect and the United States Food and Drug Administration's Adverse Event Reporting System (FAERS): analysis of sixty-two drugs approved from 2006 to 2010.

Detection of drug-drug interactions by modeling interaction profile fingerprints

Bridging islands of information to establish an integrated knowledge base of drugs and health outcomes of interest

Cooperative transcription factor associations discovered using regulatory variation

Disease risk factors identified through shared genetic architecture and electronic medical records

Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes

Connecting the Dots: Applications of Network Medicine in Pharmacology and Disease

Systems pharmacology augments drug safety surveillance

Systems biology approaches for identifying adverse drug reactions and elucidating their underlying biological mechanisms

Stimulated reporting: the impact of US food and drug administration-issued alerts on the adverse event reporting system (FAERS)

Coherent functional modules improve transcription factor target identification, cooperativity prediction, and disease association

An integrative method for scoring candidate genes from association studies: application to warfarin dosing

Similarity-based modeling applied to signal detection in pharmacovigilance.

STORMSeq: an open-source, user-friendly pipeline for processing personal genomics data in the cloud

Novel (coumarin-3-yl)carbamates as selective MAO-B inhibitors: synthesis, in vitro and in vivo assays, theoretical evaluation of ADME properties and docking study

Development and validation of a classification approach for extracting severity automatically from electronic health records

Immune complement and coagulation dysfunction in adverse outcomes of SARS-CoV-2 infection

Interpretome: a freely available, modular, and secure personal genome interpretation engine

Synthesis, pharmacological study and docking calculations of new benzo[f]coumarin derivatives as dual inhibitors of enzymatic systems involved in neurodegenerative diseases

An Integrative Data Science Pipeline to Identify Novel Drug Interactions that Prolong the QT Interval

A Computational Drug Repositioning Approach for Targeting Oncogenic Transcription Factors

State of the Art and Development of a Drug-Drug Interaction Large Scale Predictor Based on 3D Pharmacophoric Similarity

Ten Simple Rules to Enable Multi-site Collaborations through Data Sharing

Pathway analysis of genome-wide data improves warfarin dose prediction

Insight into the Functional and Structural Properties of 3-Arylcoumarin as an Interesting Scaffold in Monoamine Oxidase B Inhibition

Shotgun Transcriptome and Isothermal Profiling of SARS-CoV-2 Infection Reveals Unique Host Responses, Viral Diversification, and Drug Interactions

3D pharmacophoric similarity improves multi adverse drug event identification in pharmacovigilance

Investigation of 7-dehydrocholesterol reductase pathway to elucidate off-target prenatal effects of pharmaceuticals: a systematic review

Uncovering exposures responsible for birth season - disease effects: a global study

Columbia Open Health Data, clinical concept prevalence and co-occurrence from electronic health records

MAO Inhibitory Activity of 2-Arylbenzofurans versus 3-Arylcoumarins: Synthesis, in vitro Study, and Docking Calculations

Connectivity Homology Enables Inter-Species Network Models of Synthetic Lethality

Improving Detection of Arrhythmia Drug-Drug Interactions in Pharmacovigilance Data through the Implementation of Similarity-Based Modeling

A Pharmacovigilance Signaling System Based on FDA Regulatory Action and Post-Marketing Adverse Event Reports

Testing the association between blood type and COVID-19 infection, intubation, and death

VenomKB, a new knowledge base for facilitating the validation of putative venom therapies

Associations between blood type and COVID-19 infection, intubation, and death

Insight into the interactions between novel coumarin derivatives and human A3 adenosine receptors