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List of works by Christoph Fahlke

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Somatic and germline CACNA1D calcium channel mutations in aldosterone-producing adenomas and primary aldosteronism

scientific article
Engaging neuroscience to advance translational research in brain barrier biology.

scientific article published in March 2011
Mutations in CLCN2 encoding a voltage-gated chloride channel are associated with idiopathic generalized epilepsies

scientific article (publication date: April 2003)
An aspartic acid residue important for voltage-dependent gating of human muscle chloride channels

scientific article published on August 1995
A trimeric quaternary structure is conserved in bacterial and human glutamate transporters

scientific article
Barttin modulates trafficking and function of ClC-K channels

scientific article
Recurrent gain of function mutation in calcium channel CACNA1H causes early-onset hypertension with primary aldosteronism.

scientific article published on 24 April 2015
Molecular basis for decreased muscle chloride conductance in the myotonic goat

scientific article
Conserved dimeric subunit stoichiometry of SLC26 multifunctional anion exchangers

scientific journal article
Mechanisms of anion conduction by coupled glutamate transporters

scientific article published on January 2015
The role of the carboxyl terminus in ClC chloride channel function

scientific article published on 12 January 2004
A beta-lactam antibiotic dampens excitotoxic inflammatory CNS damage in a mouse model of multiple sclerosis

scientific article
A mutation in autosomal dominant myotonia congenita affects pore properties of the muscle chloride channel

scientific article
CLC channel function and dysfunction in health and disease

scientific article
Novel CLCN1 mutations with unique clinical and electrophysiological consequences

scientific article published in November 2002
Crystal structure of a light-driven sodium pump

scientific article
Anion permeation in human ClC-4 channels

scientific article published on April 2003
Glutamate modifies ion conduction and voltage-dependent gating of excitatory amino acid transporter-associated anion channels

scientific article published on 23 September 2003
Excitatory amino acid transporters: recent insights into molecular mechanisms, novel modes of modulation and new therapeutic possibilities.

scientific article
Molecular basis of DFNB73: mutations of BSND can cause nonsyndromic deafness or Bartter syndrome.

scientific article published on 30 July 2009
Gating of human ClC-2 chloride channels and regulation by carboxy-terminal domains

scientific article published on 18 September 2008
Disease-causing dysfunctions of barttin in Bartter syndrome type IV

scientific article published on 5 September 2008
Pore stoichiometry of a voltage-gated chloride channel

scientific article published on August 1998
Barttin activates ClC-K channel function by modulating gating

scientific article
Channel-like slippage modes in the human anion/proton exchanger ClC-4.

scientific article published on 13 April 2009
Mechanism of ion permeation in skeletal muscle chloride channels

scientific article
Physiology and pathophysiology of ClC-K/barttin channels

scientific article published on November 26, 2010
Carboxy-terminal truncations modify the outer pore vestibule of muscle chloride channels

scientific article published on 24 June 2005
ClC-3 is an intracellular chloride/proton exchanger with large voltage-dependent nonlinear capacitance

scientific article published on 4 April 2013
A missense mutation in canine C1C-1 causes recessive myotonia congenita in the dog.

scientific article published on July 1999
Two novel CLCN2 mutations accelerating chloride channel deactivation are associated with idiopathic generalized epilepsy.

scientific article
Regulation of the human skeletal muscle chloride channel hClC-1 by protein kinase C.

scientific article published on February 1999
The photophysics of LOV-based fluorescent proteins--new tools for cell biology

scientific article
CLCN2 chloride channel mutations in familial hyperaldosteronism type II.

scientific article
Neuronal glutamate transporters vary in substrate transport rate but not in unitary anion channel conductance

scientific article
Glutamate transporter-associated anion channels adjust intracellular chloride concentrations during glial maturation

scientific article published on 18 November 2016
Allosteric modulation of an excitatory amino acid transporter: the subtype-selective inhibitor UCPH-101 exerts sustained inhibition of EAAT1 through an intramonomeric site in the trimerization domain.

scientific article published in January 2013
Disease-causing mutations C277R and C277Y modify gating of human ClC-1 chloride channels in myotonia congenita

scientific article published on 28 May 2012
Intersubunit interactions in EAAT4 glutamate transporters.

scientific article published on July 2006
A point mutation associated with episodic ataxia 6 increases glutamate transporter anion currents

scientific article
CLCN2 variants in idiopathic generalized epilepsy

scientific article published on 01 September 2009
A conserved aspartate determines pore properties of anion channels associated with excitatory amino acid transporter 4 (EAAT4).

scientific article published on 2 June 2010
Functional properties of the retinal glutamate transporters GLT-1c and EAAT5

scientific journal article
Anion- and proton-dependent gating of ClC-4 anion/proton transporter under uncoupling conditions

scientific article published on March 2011
Induced fit substrate binding to an archeal glutamate transporter homologue

scientific article published on 09 July 2013
Anion transport by the cochlear motor protein prestin

scientific journal article
Molecular physiology of EAAT anion channels.

scientific article published on 19 December 2015
Involvement of ClC-3 chloride/proton exchangers in controlling glutamatergic synaptic strength in cultured hippocampal neurons.

scientific article published on 23 May 2014
Regulation of glial glutamate transporters by C-terminal domains.

scientific article published on 19 November 2010
ClC-1 and ClC-2 form hetero-dimeric channels with novel protopore functions

scientific article published on 19 March 2014

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