List of works - Elior Peles

Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

scientific article

Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan's syndrome and acquired neuromyotonia

scientific article

Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits

scientific article

The local differentiation of myelinated axons at nodes of Ranvier

scientific article

Sodium channel Na(v)1.6 is localized at nodes of ranvier, dendrites, and synapses

scientific article

Contactin orchestrates assembly of the septate-like junctions at the paranode in myelinated peripheral nerve

scientific article published in May 2001

Neu differentiation factor: a transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit

scientific article published in May 1992

Juxtaparanodal clustering of Shaker-like K+ channels in myelinated axons depends on Caspr2 and TAG-1

scientific article

Caspr2, a new member of the neurexin superfamily, is localized at the juxtaparanodes of myelinated axons and associates with K+ channels

scientific article

Identification of a novel contactin-associated transmembrane receptor with multiple domains implicated in protein-protein interactions

scientific article

Isolation of the neu/HER-2 stimulatory ligand: a 44 kd glycoprotein that induces differentiation of mammary tumor cells

scientific article

The carbonic anhydrase domain of receptor tyrosine phosphatase beta is a functional ligand for the axonal cell recognition molecule contactin

scientific article

The axonal membrane protein Caspr, a homologue of neurexin IV, is a component of the septate-like paranodal junctions that assemble during myelination

scientific article

Investigations of caspr2, an autoantigen of encephalitis and neuromyotonia

scientific article

Gliomedin mediates Schwann cell-axon interaction and the molecular assembly of the nodes of Ranvier

scientific article published in July 2005

Neu and its ligands: from an oncogene to neural factors

scientific article published on December 1993

Dependence of nodal sodium channel clustering on paranodal axoglial contact in the developing CNS.

scientific article published in September 1999

Contactin-associated protein (Caspr) and contactin form a complex that is targeted to the paranodal junctions during myelination.

scientific article

A glial signal consisting of gliomedin and NrCAM clusters axonal Na+ channels during the formation of nodes of Ranvier

scientific journal article

Molecular domains of myelinated axons in the peripheral nervous system

scientific article

Exogenous and evoked oxytocin restores social behavior in the Cntnap2 mouse model of autism

scientific article published in January 2015

Heterodimerization of the erbB-1 and erbB-2 receptors in human breast carcinoma cells: a mechanism for receptor transregulation

scientific article published on December 1990

Distinct claudins and associated PDZ proteins form different autotypic tight junctions in myelinating Schwann cells

scientific article

A myelin galactolipid, sulfatide, is essential for maintenance of ion channels on myelinated axon but not essential for initial cluster formation.

scientific article published in August 2002

Spectrins and ankyrinB constitute a specialized paranodal cytoskeleton

scientific journal article

Induction of neurite outgrowth through contactin and Nr-CAM by extracellular regions of glial receptor tyrosine phosphatase beta

scientific article

Interaction of serotonin 5-hydroxytryptamine type 2C receptors with PDZ10 of the multi-PDZ domain protein MUPP1

scientific article (publication date: 20 April 2001)

A central role for Necl4 (SynCAM4) in Schwann cell-axon interaction and myelination

scientific article

Heparan sulfate proteoglycan-dependent induction of axon branching and axon misrouting by the Kallmann syndrome gene kal-1.

scientific article

Cell-type specific interaction of Neu differentiation factor (NDF/heregulin) with Neu/HER-2 suggests complex ligand-receptor relationships

scientific article

Three mechanisms assemble central nervous system nodes of Ranvier

scientific article published on May 2013

Caspr regulates the processing of contactin and inhibits its binding to neurofascin

scientific article

Cntnap4 differentially contributes to GABAergic and dopaminergic synaptic transmission

scientific article

Mechanisms and roles of axon-Schwann cell interactions.

scientific article published in October 2004

Postsynaptic density-93 clusters Kv1 channels at axon initial segments independently of Caspr2.

scientific article published on May 2008

Localization of Caspr2 in myelinated nerves depends on axon-glia interactions and the generation of barriers along the axon

scientific journal article

Neurofascin as a target for autoantibodies in peripheral neuropathies

scientific article published on 24 October 2012

Retention of a cell adhesion complex at the paranodal junction requires the cytoplasmic region of Caspr

scientific article

Multiple molecular interactions determine the clustering of Caspr2 and Kv1 channels in myelinated axons

scientific journal article

Organization of myelinated axons by Caspr and Caspr2 requires the cytoskeletal adapter protein 4.1B

scientific article

Caspr3 and caspr4, two novel members of the caspr family are expressed in the nervous system and interact with PDZ domains

scientific article

ADAM22, a Kv1 channel-interacting protein, recruits membrane-associated guanylate kinases to juxtaparanodes of myelinated axons

scientific journal article

Myelinating Schwann cells determine the internodal localization of Kv1.1, Kv1.2, Kvbeta2, and Caspr

scientific article published in April 1999

Multi-ligand interactions with receptor-like protein tyrosine phosphatase beta: implications for intercellular signaling

scientific article

Cell-contact-dependent signalling in axon growth and guidance: Eph receptor tyrosine kinases and receptor protein tyrosine phosphatase beta

scientific article

Secreted gliomedin is a perinodal matrix component of peripheral nerves

scientific article

K+ channel distribution and clustering in developing and hypomyelinated axons of the optic nerve

scientific article published in April 1999

Development of nodes of Ranvier

scientific article

Ermin, a myelinating oligodendrocyte-specific protein that regulates cell morphology

scientific journal article

ErbB-3 and ErbB-4 function as the respective low and high affinity receptors of all Neu differentiation factor/heregulin isoforms

scientific journal article

List of works by Elior Peles

Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan's syndrome and acquired neuromyotonia

Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits

The local differentiation of myelinated axons at nodes of Ranvier

Sodium channel Na(v)1.6 is localized at nodes of ranvier, dendrites, and synapses

Contactin orchestrates assembly of the septate-like junctions at the paranode in myelinated peripheral nerve

Neu differentiation factor: a transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit

Juxtaparanodal clustering of Shaker-like K+ channels in myelinated axons depends on Caspr2 and TAG-1

Caspr2, a new member of the neurexin superfamily, is localized at the juxtaparanodes of myelinated axons and associates with K+ channels

Identification of a novel contactin-associated transmembrane receptor with multiple domains implicated in protein-protein interactions

Isolation of the neu/HER-2 stimulatory ligand: a 44 kd glycoprotein that induces differentiation of mammary tumor cells

The carbonic anhydrase domain of receptor tyrosine phosphatase beta is a functional ligand for the axonal cell recognition molecule contactin

The axonal membrane protein Caspr, a homologue of neurexin IV, is a component of the septate-like paranodal junctions that assemble during myelination

Investigations of caspr2, an autoantigen of encephalitis and neuromyotonia

Gliomedin mediates Schwann cell-axon interaction and the molecular assembly of the nodes of Ranvier

Neu and its ligands: from an oncogene to neural factors

Dependence of nodal sodium channel clustering on paranodal axoglial contact in the developing CNS.

Contactin-associated protein (Caspr) and contactin form a complex that is targeted to the paranodal junctions during myelination.

A glial signal consisting of gliomedin and NrCAM clusters axonal Na+ channels during the formation of nodes of Ranvier

Molecular domains of myelinated axons in the peripheral nervous system

Exogenous and evoked oxytocin restores social behavior in the Cntnap2 mouse model of autism

Heterodimerization of the erbB-1 and erbB-2 receptors in human breast carcinoma cells: a mechanism for receptor transregulation

Distinct claudins and associated PDZ proteins form different autotypic tight junctions in myelinating Schwann cells

A myelin galactolipid, sulfatide, is essential for maintenance of ion channels on myelinated axon but not essential for initial cluster formation.

Spectrins and ankyrinB constitute a specialized paranodal cytoskeleton

Induction of neurite outgrowth through contactin and Nr-CAM by extracellular regions of glial receptor tyrosine phosphatase beta

Interaction of serotonin 5-hydroxytryptamine type 2C receptors with PDZ10 of the multi-PDZ domain protein MUPP1

A central role for Necl4 (SynCAM4) in Schwann cell-axon interaction and myelination

Heparan sulfate proteoglycan-dependent induction of axon branching and axon misrouting by the Kallmann syndrome gene kal-1.

Cell-type specific interaction of Neu differentiation factor (NDF/heregulin) with Neu/HER-2 suggests complex ligand-receptor relationships

Three mechanisms assemble central nervous system nodes of Ranvier

Caspr regulates the processing of contactin and inhibits its binding to neurofascin

Cntnap4 differentially contributes to GABAergic and dopaminergic synaptic transmission

Mechanisms and roles of axon-Schwann cell interactions.

Postsynaptic density-93 clusters Kv1 channels at axon initial segments independently of Caspr2.

Localization of Caspr2 in myelinated nerves depends on axon-glia interactions and the generation of barriers along the axon

Neurofascin as a target for autoantibodies in peripheral neuropathies

Retention of a cell adhesion complex at the paranodal junction requires the cytoplasmic region of Caspr

Multiple molecular interactions determine the clustering of Caspr2 and Kv1 channels in myelinated axons

Organization of myelinated axons by Caspr and Caspr2 requires the cytoskeletal adapter protein 4.1B

Caspr3 and caspr4, two novel members of the caspr family are expressed in the nervous system and interact with PDZ domains

ADAM22, a Kv1 channel-interacting protein, recruits membrane-associated guanylate kinases to juxtaparanodes of myelinated axons

Myelinating Schwann cells determine the internodal localization of Kv1.1, Kv1.2, Kvbeta2, and Caspr

Multi-ligand interactions with receptor-like protein tyrosine phosphatase beta: implications for intercellular signaling

Cell-contact-dependent signalling in axon growth and guidance: Eph receptor tyrosine kinases and receptor protein tyrosine phosphatase beta

Secreted gliomedin is a perinodal matrix component of peripheral nerves

K+ channel distribution and clustering in developing and hypomyelinated axons of the optic nerve

Development of nodes of Ranvier

Ermin, a myelinating oligodendrocyte-specific protein that regulates cell morphology

ErbB-3 and ErbB-4 function as the respective low and high affinity receptors of all Neu differentiation factor/heregulin isoforms