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List of works by Matthias Dobbelstein

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p63 antagonizes Wnt-induced transcription

scientific article published in February 2010
Bcl-xL mediates therapeutic resistance of a mesenchymal breast cancer cell subpopulation.

scientific article
A killer promoting survival: p53 as a selective means to avoid side effects of chemotherapy

scientific article published on 01 June 2012
Mutual interference of adenovirus infection and myc expression

scientific article
Efficient replication of adenovirus despite the overexpression of active and nondegradable p53.

scientific article
Wee1 is required to sustain ATR/Chk1 signaling upon replicative stress

scientific article
Usp22 deficiency impairs intestinal epithelial lineage specification in vivo

scientific article published on 25 September 2015
UDP glucuronosyltransferase 1A expression levels determine the response of colorectal cancer cells to the heat shock protein 90 inhibitor ganetespib

scientific article
A promoter that acquired p53 responsiveness during primate evolution

scientific article published on 01 April 2003
Viral and cellular factors that target the promyelocytic leukemia oncogenic domains strongly activate a glucocorticoid-responsive promoter

scientific article published on June 2001
The MAPK-activated protein kinase 2 mediates gemcitabine sensitivity in pancreatic cancer cells

scientific article published on 21 February 2014
Comprehensive identification of genes driven by ERV9-LTRs reveals TNFRSF10B as a re-activatable mediator of testicular cancer cell death

scientific article published on 29 May 2015
Infection with E1B-mutant adenovirus stabilizes p53 but blocks p53 acetylation and activity through E1A.

scientific article published on 11 October 2010
Brdm2 - an aberrant hypomorphic p63 allele

scientific article published on January 2010
Doxorubicin-induced activation of NF-κB in melanoma cells is abrogated by inhibition of IKKβ, but not by a novel IKKα inhibitor

scientific article published on 10 February 2012
Anthracyclines induce the accumulation of mutant p53 through E2F1-dependent and -independent mechanisms

scientific article published on 28 March 2011
Chromatin modifiers Mdm2 and RNF2 prevent RNA:DNA hybrids that impair DNA replication

article published in the Proceedings of the National Academy of Sciences of the United States of America
Adenovirus E1-transformed cells grow despite the continuous presence of transcriptionally active p53.

scientific article published on August 2002
5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair

scientific article published on May 2015
Overcoming EMT-driven therapeutic resistance by BH3 mimetics

scientific article published on 5 November 2014
Enhanced cytotoxicity without internuclear spread of adenovirus upon cell fusion by measles virus glycoproteins.

scientific article
A pro-apoptotic function of iASPP by stabilizing p300 and CBP through inhibition of BRMS1 E3 ubiquitin ligase activity

scientific article published on 12 February 2015
Rev protein of human immunodeficiency virus type 1 and cellular exportin 1 protein relocalize each other to a subnucleolar structure

scientific article published in June 2000
Cell cycle arrest or apoptosis by p53: are microRNAs-192/215 and -34 making the decision?

scientific article published on 9 March 2009
HSP90 inhibitor antagonizing MIF: The specifics of pleiotropic cancer drug candidates

scientific article published on November 2012
Screening analysis of ubiquitin ligases reveals G2E3 as a potential target for chemosensitizing cancer cells

scientific article
Interchanging heads: p53 re-composes the DREAM/MMB complex to repress transcription

scientific article published on 19 December 2012
Mdm2 inhibition confers protection of p53-proficient cells from the cytotoxic effects of Wee1 inhibitors

scientific article
Interaction of p53 with the adenovirus E1B-55 kDa protein

scientific article published on 01 January 2003
Inhibition of MAPKAPK2/MK2 facilitates DNA replication upon cancer cell treatment with gemcitabine but not cisplatin

scientific article published on 25 April 2018
Activating Ras mutations fail to ensure efficient replication of adenovirus mutants lacking VA-RNA.

scientific article
Reactivation of mutant p53 by a one-hybrid adaptor protein.

scientific article published in July 2003
Non-hominid TP63 lacks retroviral LTRs but contains a novel conserved upstream exon

scientific article published on 15 June 2011
Self-association of adenovirus type 5 E1B-55 kDa as well as p53 is essential for their mutual interaction

scientific article
G2E3 attenuating replicative stress

scientific article published on 18 August 2015
Wee1 and Chk1 - crosstalk between key players in replicative stress

scientific article published on May 2015
Mdm2 - open questions

scientific article published on 26 April 2020
Supplementary Material 1 from GANNET53 Part II: A European Phase I/II Trial of the HSP90 Inhibitor Ganetespib in High-Grade Platinum-Resistant Ovarian Cancer—A Study of the GANNET53 Consortium

Data from GANNET53 Part II: A European Phase I/II Trial of the HSP90 Inhibitor Ganetespib in High-Grade Platinum-Resistant Ovarian Cancer—A Study of the GANNET53 Consortium

Neutralization of SARS-CoV-2 by highly potent, hyperthermostable, and mutation-tolerant nanobodies

scientific article published on 09 August 2021
The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis

scientific article published on 23 July 2020
Inhibiting the HSP90 chaperone destabilizes macrophage migration inhibitory factor and thereby inhibits breast tumor progression

scientific article published in March 2012
E1A genes of adenovirus type 2 and type 5 are expressed at different levels

scientific article published on 19 January 2006
GANNET53 Part II: A European Phase I/II Trial of the HSP90 Inhibitor Ganetespib in High-Grade Platinum-Resistant Ovarian Cancer—A Study of the GANNET53 Consortium

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