List of works - Ian P. Hall

Effects of genetic polymorphism on ex vivo and in vivo function of beta2-adrenoceptors in asthmatic patients

scientific article

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

scientific article published on 25 February 2019

A major functional role for phosphodiesterase 4D5 in human airway smooth muscle cells

scientific article published on 2 August 2007

Reverse mode Na+/Ca2+ exchange mediated by STIM1 contributes to Ca2+ influx in airway smooth muscle following agonist stimulation

scientific article

GSTCD and INTS12 regulation and expression in the human lung

scientific article

A biomechanical model of agonist-initiated contraction in the asthmatic airway

scientific article published on 22 November 2009

Influence of agonist efficacy and receptor phosphorylation on antagonist affinity measurements: differences between second messenger and reporter gene responses

scientific article published in September 2003

Glucocorticoids increase repair potential in a novel in vitro human airway epithelial wounding model

scientific article

Possible role of the 4G/5G polymorphism of the plasminogen activator inhibitor 1 gene in the development of asthma

scientific article published on 01 August 2001

Opportunities and challenges in the genetics of COPD 2010: an International COPD Genetics Conference report

scientific article

Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels

scientific article

Pharmacogenetics of asthma

scientific article

Molecular mechanisms underlying variations in lung function: a systems genetics analysis

scientific article published on 21 September 2015

Novel cAMP signalling paradigms: therapeutic implications for airway disease

scientific article published on May 2012

The UK prevalence of hereditary haemorrhagic telangiectasia and its association with sex, socioeconomic status and region of residence: a population-based study.

scientific article published on 4 November 2013

Pharmacology and direct visualisation of BODIPY-TMR-CGP: a long-acting fluorescent beta2-adrenoceptor agonist

scientific article published on May 2003

Pharmacological characterization of CGP 12177 at the human beta(2)-adrenoceptor

scientific article published in October 2002

Genetic association studies in Thorax

scientific article published in May 2005

Effects of a range of beta2 adrenoceptor agonists on changes in intracellular cyclic AMP and on cyclic AMP driven gene expression in cultured human airway smooth muscle cells

scientific article

Complications and mortality in hereditary hemorrhagic telangiectasia: A population-based study.

scientific article published on 10 April 2015

The Selective CXCR2 Antagonist SB272844 Blocks Interleukin-8 and Growth-related Oncogene-α-mediated Inhibition of Spontaneous Neutrophil Apoptosis

scientific article published on 01 January 2002

Whole exome re-sequencing implicates CCDC38 and cilia structure and function in resistance to smoking related airflow obstruction.

scientific article

Modulation of carbachol-induced inositol phosphate formation in bovine tracheal smooth muscle by cyclic AMP phosphodiesterase inhibitors

scientific article published on 01 April 1990

Purulent pericarditis

scientific article published on July 1989

Temporal characteristics of cAMP response element-mediated gene transcription: requirement for sustained cAMP production

scientific article published in April 2004

5-Lipoxygenase polymorphism and in-vivo response to leukotriene receptor antagonists

scientific article published on 17 May 2002

Detection of mutations in KLHL3 and CUL3 in families with FHHt (familial hyperkalaemic hypertension or Gordon's syndrome).

scientific article published on May 2014

β2 Agonists

scientific article published on 23 November 2016

Extracellular matrix modulates beta2-adrenergic receptor signaling in human airway smooth muscle cells

scientific article

Airway myofibroblasts and their relationship with airway myocytes and fibroblasts

scientific article published on January 2008

Integrative pathway genomics of lung function and airflow obstruction

scientific article

The Ser82 RAGE Variant Affects Lung Function and Serum RAGE in Smokers and sRAGE Production In Vitro

scientific article

Discoidin domain receptor 1 regulates bronchial epithelial repair and matrix metalloproteinase production

scientific article published on 30 September 2010

Novel polymorphisms influencing transcription of the human CHRM2 gene in airway smooth muscle

scientific article published on 25 September 2003

A genome-wide association study to identify genetic determinants of atopy in subjects from the United Kingdom

article

Are beta2-adrenoceptor polymorphisms important in asthma--an unravelling story

scientific article published in October 2004

PLAUR polymorphisms and lung function in UK smokers

scientific article

Eosinophil-mediated cholinergic nerve remodeling.

scientific article published on 2 February 2006

A rare missense mutation in CHRNA4 associates with smoking behavior and its consequences

scientific article

A systematic review and meta-analysis of thiazide-induced hyponatraemia: time to reconsider electrolyte monitoring regimens after thiazide initiation?

scientific article

Nickel induces intracellular calcium mobilization and pathophysiological responses in human cultured airway epithelial cells.

scientific article published in January 2010

Genetic variation at the growth hormone (GH1) and growth hormone receptor (GHR) loci as a risk factor for hypertension and stroke

article

Phenotypic and pharmacogenetic evaluation of patients with thiazide-induced hyponatremia

scientific article published on 7 August 2017

Targeted inhibition of Gq signaling induces airway relaxation in mouse models of asthma

scientific article published in September 2017

The beta-agonist controversy revisited

scientific article

The role of inflammation resolution speed in airway smooth muscle mass accumulation in asthma: insight from a theoretical model

scientific article

Pharmacogenetics of asthma

scientific article published on 01 March 2000

The effect of beta2-adrenoceptor agonists on phospholipase C (beta1) signalling in human airway smooth muscle cells.

scientific article published on 17 January 2006

Bradykinin activates calcium-dependent potassium channels in cultured human airway smooth muscle cells

scientific article published on 8 December 2006

A Genome-wide Association Study in Hispanics/Latinos Identifies Novel Signals for Lung Function. The Hispanic Community Health Study/Study of Latinos.

scientific article published on 2 February 2018

List of works by Ian P. Hall

Effects of genetic polymorphism on ex vivo and in vivo function of beta2-adrenoceptors in asthmatic patients

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

A major functional role for phosphodiesterase 4D5 in human airway smooth muscle cells

Reverse mode Na+/Ca2+ exchange mediated by STIM1 contributes to Ca2+ influx in airway smooth muscle following agonist stimulation

GSTCD and INTS12 regulation and expression in the human lung

A biomechanical model of agonist-initiated contraction in the asthmatic airway

Influence of agonist efficacy and receptor phosphorylation on antagonist affinity measurements: differences between second messenger and reporter gene responses

Glucocorticoids increase repair potential in a novel in vitro human airway epithelial wounding model

Possible role of the 4G/5G polymorphism of the plasminogen activator inhibitor 1 gene in the development of asthma

Opportunities and challenges in the genetics of COPD 2010: an International COPD Genetics Conference report

Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels

Pharmacogenetics of asthma

Molecular mechanisms underlying variations in lung function: a systems genetics analysis

Novel cAMP signalling paradigms: therapeutic implications for airway disease

The UK prevalence of hereditary haemorrhagic telangiectasia and its association with sex, socioeconomic status and region of residence: a population-based study.

Pharmacology and direct visualisation of BODIPY-TMR-CGP: a long-acting fluorescent beta2-adrenoceptor agonist

Pharmacological characterization of CGP 12177 at the human beta(2)-adrenoceptor

Genetic association studies in Thorax

Effects of a range of beta2 adrenoceptor agonists on changes in intracellular cyclic AMP and on cyclic AMP driven gene expression in cultured human airway smooth muscle cells

Complications and mortality in hereditary hemorrhagic telangiectasia: A population-based study.

The Selective CXCR2 Antagonist SB272844 Blocks Interleukin-8 and Growth-related Oncogene-α-mediated Inhibition of Spontaneous Neutrophil Apoptosis

Whole exome re-sequencing implicates CCDC38 and cilia structure and function in resistance to smoking related airflow obstruction.

Modulation of carbachol-induced inositol phosphate formation in bovine tracheal smooth muscle by cyclic AMP phosphodiesterase inhibitors

Purulent pericarditis

Temporal characteristics of cAMP response element-mediated gene transcription: requirement for sustained cAMP production

5-Lipoxygenase polymorphism and in-vivo response to leukotriene receptor antagonists

Detection of mutations in KLHL3 and CUL3 in families with FHHt (familial hyperkalaemic hypertension or Gordon's syndrome).

β2 Agonists

Extracellular matrix modulates beta2-adrenergic receptor signaling in human airway smooth muscle cells

Airway myofibroblasts and their relationship with airway myocytes and fibroblasts

Integrative pathway genomics of lung function and airflow obstruction

The Ser82 RAGE Variant Affects Lung Function and Serum RAGE in Smokers and sRAGE Production In Vitro

Discoidin domain receptor 1 regulates bronchial epithelial repair and matrix metalloproteinase production

Novel polymorphisms influencing transcription of the human CHRM2 gene in airway smooth muscle

A genome-wide association study to identify genetic determinants of atopy in subjects from the United Kingdom

Are beta2-adrenoceptor polymorphisms important in asthma--an unravelling story

PLAUR polymorphisms and lung function in UK smokers

Eosinophil-mediated cholinergic nerve remodeling.

A rare missense mutation in CHRNA4 associates with smoking behavior and its consequences

A systematic review and meta-analysis of thiazide-induced hyponatraemia: time to reconsider electrolyte monitoring regimens after thiazide initiation?

Nickel induces intracellular calcium mobilization and pathophysiological responses in human cultured airway epithelial cells.

Genetic variation at the growth hormone (GH1) and growth hormone receptor (GHR) loci as a risk factor for hypertension and stroke

Phenotypic and pharmacogenetic evaluation of patients with thiazide-induced hyponatremia

Targeted inhibition of Gq signaling induces airway relaxation in mouse models of asthma

The beta-agonist controversy revisited

The role of inflammation resolution speed in airway smooth muscle mass accumulation in asthma: insight from a theoretical model

Pharmacogenetics of asthma

The effect of beta2-adrenoceptor agonists on phospholipase C (beta1) signalling in human airway smooth muscle cells.

Bradykinin activates calcium-dependent potassium channels in cultured human airway smooth muscle cells

A Genome-wide Association Study in Hispanics/Latinos Identifies Novel Signals for Lung Function. The Hispanic Community Health Study/Study of Latinos.