List of works - Jeroen Demmers

Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

scientific article

An Oct4-centered protein interaction network in embryonic stem cells

scientific article

RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3

scientific article

Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity

scientific article

STIM1 is a MT-plus-end-tracking protein involved in remodeling of the ER.

scientific article

Exosome-mediated transmission of hepatitis C virus between human hepatoma Huh7.5 cells.

scientific article published on 22 July 2013

Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators.

scientific article published on 16 May 2010

Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4

scientific article

CLASPs attach microtubule plus ends to the cell cortex through a complex with LL5beta

scientific article

Rab6 regulates transport and targeting of exocytotic carriers

scientific article published on August 2007

Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor

scientific journal article

TRAK/Milton motor-adaptor proteins steer mitochondrial trafficking to axons and dendrites

scientific journal article

dKDM2 couples histone H2A ubiquitylation to histone H3 demethylation during Polycomb group silencing

scientific article

Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry

scientific article

Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes

scientific journal article

Motor neuron disease-associated mutant vesicle-associated membrane protein-associated protein (VAP) B recruits wild-type VAPs into endoplasmic reticulum-derived tubular aggregates.

scientific article published on September 2007

A Proteome-wide screen for mammalian SxIP motif-containing microtubule plus-end tracking proteins

scientific article

Estrogen-related receptor beta interacts with Oct4 to positively regulate Nanog gene expression

scientific journal article

Interfacial anchor properties of tryptophan residues in transmembrane peptides can dominate over hydrophobic matching effects in peptide-lipid interactions

scientific article published in May 2003

BICD2, dynactin, and LIS1 cooperate in regulating dynein recruitment to cellular structures

scientific article

Histone chaperones ASF1 and NAP1 differentially modulate removal of active histone marks by LID-RPD3 complexes during NOTCH silencing

scientific article published in September 2009

The BAF complex interacts with Pax6 in adult neural progenitors to establish a neurogenic cross-regulatory transcriptional network.

scientific article published on 08 August 2013

UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair

scientific article

The core spliceosome as target and effector of non-canonical ATM signalling.

scientific article

RNF12 initiates X-chromosome inactivation by targeting REX1 for degradation

scientific article published on 29 April 2012

MiR-17/20/93/106 promote hematopoietic cell expansion by targeting sequestosome 1-regulated pathways in mice

scientific article

Rab6, Rab8, and MICAL3 cooperate in controlling docking and fusion of exocytotic carriers

scientific article published on 19 May 2011

SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase

scientific article

ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN.

scientific article published on 15 May 2013

Nuclear receptors TR2 and TR4 recruit multiple epigenetic transcriptional corepressors that associate specifically with the embryonic β-type globin promoters in differentiated adult erythroid cells

scientific article

Return to quiescence of mouse neural stem cells by degradation of a proactivation protein.

scientific article

ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes

scientific journal article

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal

scientific journal article

RAD51AP1 is a structure-specific DNA binding protein that stimulates joint molecule formation during RAD51-mediated homologous recombination

scientific article published in November 2007

CFEOM1-associated kinesin KIF21A is a cortical microtubule growth inhibitor.

scientific article published on 10 October 2013

NMDA receptor activation suppresses microtubule growth and spine entry

scientific journal article

Electrospray ionization mass spectrometry as a tool to analyze hydrogen/deuterium exchange kinetics of transmembrane peptides in lipid bilayers.

scholarly article

VEGFR2 translocates to the nucleus to regulate its own transcription

scientific article

Liprin-α2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmission

scientific article published on June 2013

Polycomblike 2 facilitates the recruitment of PRC2 Polycomb group complexes to the inactive X chromosome and to target loci in embryonic stem cells

scientific article

Identification of differential protein interactors of lamin A and progerin

scientific article

Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors

scientific article published on April 2009

Remodelers organize cellular chromatin by counteracting intrinsic histone-DNA sequence preferences in a class-specific manner

scientific article published on 28 November 2011

Interactions between phage-shock proteins in Escherichia coli

scientific article

CTCF regulates the local epigenetic state of ribosomal DNA repeats

scientific article

Identification of delta/notch-like epidermal growth factor-related receptor as the Tr antigen in paraneoplastic cerebellar degeneration

scientific article

BRCA1185delAG tumors may acquire therapy resistance through expression of RING-less BRCA1

scientific article published on 25 July 2016

Nucleotide biosynthetic enzyme GMP synthase is a TRIM21-controlled relay of p53 stabilization

scientific article published on 23 January 2014

Proteins that bind regulatory regions identified by histone modification chromatin immunoprecipitations and mass spectrometry.

scientific article published on 20 May 2015

Interfacial positioning and stability of transmembrane peptides in lipid bilayers studied by combining hydrogen/deuterium exchange and mass spectrometry

scientific article published on 2 July 2001

List of works by Jeroen Demmers

Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

An Oct4-centered protein interaction network in embryonic stem cells

RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3

Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity

STIM1 is a MT-plus-end-tracking protein involved in remodeling of the ER.

Exosome-mediated transmission of hepatitis C virus between human hepatoma Huh7.5 cells.

Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators.

Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4

CLASPs attach microtubule plus ends to the cell cortex through a complex with LL5beta

Rab6 regulates transport and targeting of exocytotic carriers

Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor

TRAK/Milton motor-adaptor proteins steer mitochondrial trafficking to axons and dendrites

dKDM2 couples histone H2A ubiquitylation to histone H3 demethylation during Polycomb group silencing

Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry

Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes

Motor neuron disease-associated mutant vesicle-associated membrane protein-associated protein (VAP) B recruits wild-type VAPs into endoplasmic reticulum-derived tubular aggregates.

A Proteome-wide screen for mammalian SxIP motif-containing microtubule plus-end tracking proteins

Estrogen-related receptor beta interacts with Oct4 to positively regulate Nanog gene expression

Interfacial anchor properties of tryptophan residues in transmembrane peptides can dominate over hydrophobic matching effects in peptide-lipid interactions

BICD2, dynactin, and LIS1 cooperate in regulating dynein recruitment to cellular structures

Histone chaperones ASF1 and NAP1 differentially modulate removal of active histone marks by LID-RPD3 complexes during NOTCH silencing

The BAF complex interacts with Pax6 in adult neural progenitors to establish a neurogenic cross-regulatory transcriptional network.

UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair

The core spliceosome as target and effector of non-canonical ATM signalling.

RNF12 initiates X-chromosome inactivation by targeting REX1 for degradation

MiR-17/20/93/106 promote hematopoietic cell expansion by targeting sequestosome 1-regulated pathways in mice

Rab6, Rab8, and MICAL3 cooperate in controlling docking and fusion of exocytotic carriers

SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase

ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN.

Nuclear receptors TR2 and TR4 recruit multiple epigenetic transcriptional corepressors that associate specifically with the embryonic β-type globin promoters in differentiated adult erythroid cells

Return to quiescence of mouse neural stem cells by degradation of a proactivation protein.

ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal

RAD51AP1 is a structure-specific DNA binding protein that stimulates joint molecule formation during RAD51-mediated homologous recombination

CFEOM1-associated kinesin KIF21A is a cortical microtubule growth inhibitor.

NMDA receptor activation suppresses microtubule growth and spine entry

Electrospray ionization mass spectrometry as a tool to analyze hydrogen/deuterium exchange kinetics of transmembrane peptides in lipid bilayers.

VEGFR2 translocates to the nucleus to regulate its own transcription

Liprin-α2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmission

Polycomblike 2 facilitates the recruitment of PRC2 Polycomb group complexes to the inactive X chromosome and to target loci in embryonic stem cells

Identification of differential protein interactors of lamin A and progerin

Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors

Remodelers organize cellular chromatin by counteracting intrinsic histone-DNA sequence preferences in a class-specific manner

Interactions between phage-shock proteins in Escherichia coli

CTCF regulates the local epigenetic state of ribosomal DNA repeats

Identification of delta/notch-like epidermal growth factor-related receptor as the Tr antigen in paraneoplastic cerebellar degeneration

BRCA1185delAG tumors may acquire therapy resistance through expression of RING-less BRCA1

Nucleotide biosynthetic enzyme GMP synthase is a TRIM21-controlled relay of p53 stabilization

Proteins that bind regulatory regions identified by histone modification chromatin immunoprecipitations and mass spectrometry.

Interfacial positioning and stability of transmembrane peptides in lipid bilayers studied by combining hydrogen/deuterium exchange and mass spectrometry