List of works - Åslaug Helland

Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers

scientific article

Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer

scientific article

Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity

scientific article published on 23 January 2014

Dabrafenib plus trametinib in patients with previously untreated BRAFV600E-mutant metastatic non-small-cell lung cancer: an open-label, phase 2 trial.

scientific article published on 8 September 2017

Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers

scientific article

Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signaling

scientific article published on 9 September 2011

Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking.

scientific article

Stromal CD8+ T-cell Density—A Promising Supplement to TNM Staging in Non–Small Cell Lung Cancer

scientific article published on 13 February 2015

Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids

scientific article

Genome-wide DNA methylation profiles in progression to in situ and invasive carcinoma of the breast with impact on gene transcription and prognosis

scientific article

TP53 codon 72 polymorphism and cervical cancer: a pooled analysis of individual data from 49 studies.

scientific article

Glycan gene expression signatures in normal and malignant breast tissue; possible role in diagnosis and progression

scientific article published on 11 December 2009

PIK3CA mutations in advanced ovarian carcinomas

scientific article published in March 2005

p53 polymorphism and risk of cervical cancer

scientific article published on 01 December 1998

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.

scientific article

Strategies for clinical implementation of TNM-Immunoscore in resected nonsmall-cell lung cancer

scientific article

Association of N-Glycosylation with Breast Carcinoma and Systemic Features Using High-Resolution Quantitative UPLC

scientific article published on 11 April 2014

Alectinib versus chemotherapy in crizotinib-pretreated anaplastic lymphoma kinase (ALK)-positive non-small-cell lung cancer: results from the phase III ALUR study

scientific article published on 14 April 2018

Unique microRNA-profiles in EGFR-mutated lung adenocarcinomas

scientific article

A unique set of 6 circulating microRNAs for early detection of non-small cell lung cancer

scientific article published on 14 May 2016

Identification of novel fusion genes in lung cancer using breakpoint assembly of transcriptome sequencing data

scientific article

Sex-specific trends in lung cancer incidence and survival: a population study of 40,118 cases

scientific article published on 2 January 2011

BRAF-mutations in non-small cell lung cancer

scientific article published on 3 February 2014

Lysophosphatidic acid-induced transcriptional profile represents serous epithelial ovarian carcinoma and worsened prognosis

scientific article

Clinicopathological characteristics of 11 NSCLC patients with EGFR-exon 20 mutations

scientific article published in September 2012

Microsatellite instability in cervical and endometrial carcinomas

scientific article published on 01 March 1997

Protein expression and prognostic value of genes in the erb-b signaling pathway in advanced ovarian carcinomas

scientific article published on 01 September 2005

Genetic alterations of the TP53 gene, p53 protein expression and hpv infection in primary cervical carcinomas

article

Years of life lost as a measure of cancer burden on a national level

scientific article

Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors.

scientific article published on 13 March 2018

Osteopontin is a prognostic biomarker in non-small cell lung cancer

scientific article

Glycan-related gene expression signatures in breast cancer subtypes; relation to survival

scientific article published on 14 January 2015

Immunohistochemical analysis of p53 protein overexpression in normal, premalignant, and malignant tissues of the cervix uteri

scientific article published on 01 January 1993

Effect of the codon 72 polymorphism (c.215G>C, p.Arg72Pro) in combination with somatic sequence variants in the TP53 gene on survival in patients with advanced ovarian carcinoma

scientific article

Expression levels of uridine 5'-diphospho-glucuronosyltransferase genes in breast tissue from healthy women are associated with mammographic density

scientific article

EGFR gene alterations in a Norwegian cohort of lung cancer patients selected for surgery

scientific article

Gene expression profiles of breast biopsies from healthy women identify a group with claudin-low features

scientific article published on November 2011

HLA antigens and cervical carcinoma

scientific article

Subtype-specific micro-RNA expression signatures in breast cancer progression

scientific article

Genome-wide DNA methylation analyses in lung adenocarcinomas: Association with EGFR, KRAS and TP53 mutation status, gene expression and prognosis

scientific article published on 6 November 2015

TP53 Mutation Spectrum in Smokers and Never Smoking Lung Cancer Patients

scientific article published on 11 May 2016

Immune Cell Composition in Human Non-small Cell Lung Cancer

article

TP53 mutations in early-stage ovarian carcinoma, relation to long-term survival

scientific article published on February 2004

Serum estradiol levels associated with specific gene expression patterns in normal breast tissue and in breast carcinomas

scientific article

Two Distinct Categories of Focal Deletions in Cancer Genomes

scientific article

High levels of genomic aberrations in serous ovarian cancers are associated with better survival

scientific article

Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression

scientific article published on 11 June 2015

Profiling of microRNAs in tumor interstitial fluid of breast tumors - a novel resource to identify biomarkers for prognostic classification and detection of cancer

scientific article

Incidence and Survival of Malignant Pleural Mesothelioma in Norway: A Population-Based Study of 1686 Cases

scientific article published on 01 December 2012

Real-world data on nivolumab treatment of non-small cell lung cancer

scientific article

List of works by Åslaug Helland

Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers

Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer

Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity

Dabrafenib plus trametinib in patients with previously untreated BRAFV600E-mutant metastatic non-small-cell lung cancer: an open-label, phase 2 trial.

Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers

Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signaling

Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking.

Stromal CD8+ T-cell Density—A Promising Supplement to TNM Staging in Non–Small Cell Lung Cancer

Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids

Genome-wide DNA methylation profiles in progression to in situ and invasive carcinoma of the breast with impact on gene transcription and prognosis

TP53 codon 72 polymorphism and cervical cancer: a pooled analysis of individual data from 49 studies.

Glycan gene expression signatures in normal and malignant breast tissue; possible role in diagnosis and progression

PIK3CA mutations in advanced ovarian carcinomas

p53 polymorphism and risk of cervical cancer

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.

Strategies for clinical implementation of TNM-Immunoscore in resected nonsmall-cell lung cancer

Association of N-Glycosylation with Breast Carcinoma and Systemic Features Using High-Resolution Quantitative UPLC

Alectinib versus chemotherapy in crizotinib-pretreated anaplastic lymphoma kinase (ALK)-positive non-small-cell lung cancer: results from the phase III ALUR study

Unique microRNA-profiles in EGFR-mutated lung adenocarcinomas

A unique set of 6 circulating microRNAs for early detection of non-small cell lung cancer

Identification of novel fusion genes in lung cancer using breakpoint assembly of transcriptome sequencing data

Sex-specific trends in lung cancer incidence and survival: a population study of 40,118 cases

BRAF-mutations in non-small cell lung cancer

Lysophosphatidic acid-induced transcriptional profile represents serous epithelial ovarian carcinoma and worsened prognosis

Clinicopathological characteristics of 11 NSCLC patients with EGFR-exon 20 mutations

Microsatellite instability in cervical and endometrial carcinomas

Protein expression and prognostic value of genes in the erb-b signaling pathway in advanced ovarian carcinomas

Genetic alterations of the TP53 gene, p53 protein expression and hpv infection in primary cervical carcinomas

Years of life lost as a measure of cancer burden on a national level

Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors.

Osteopontin is a prognostic biomarker in non-small cell lung cancer

Glycan-related gene expression signatures in breast cancer subtypes; relation to survival

Immunohistochemical analysis of p53 protein overexpression in normal, premalignant, and malignant tissues of the cervix uteri

Effect of the codon 72 polymorphism (c.215G>C, p.Arg72Pro) in combination with somatic sequence variants in the TP53 gene on survival in patients with advanced ovarian carcinoma

Expression levels of uridine 5'-diphospho-glucuronosyltransferase genes in breast tissue from healthy women are associated with mammographic density

EGFR gene alterations in a Norwegian cohort of lung cancer patients selected for surgery

Gene expression profiles of breast biopsies from healthy women identify a group with claudin-low features

HLA antigens and cervical carcinoma

Subtype-specific micro-RNA expression signatures in breast cancer progression

Genome-wide DNA methylation analyses in lung adenocarcinomas: Association with EGFR, KRAS and TP53 mutation status, gene expression and prognosis

TP53 Mutation Spectrum in Smokers and Never Smoking Lung Cancer Patients

Immune Cell Composition in Human Non-small Cell Lung Cancer

TP53 mutations in early-stage ovarian carcinoma, relation to long-term survival

Serum estradiol levels associated with specific gene expression patterns in normal breast tissue and in breast carcinomas

Two Distinct Categories of Focal Deletions in Cancer Genomes

High levels of genomic aberrations in serous ovarian cancers are associated with better survival

Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression

Profiling of microRNAs in tumor interstitial fluid of breast tumors - a novel resource to identify biomarkers for prognostic classification and detection of cancer

Incidence and Survival of Malignant Pleural Mesothelioma in Norway: A Population-Based Study of 1686 Cases

Real-world data on nivolumab treatment of non-small cell lung cancer