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List of works by Alexander J. Lazar

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Correlation between KIT expression and KIT mutation in melanoma: a study of 173 cases with emphasis on the acral-lentiginous/mucosal type

scientific article
Dermatofibrosarcoma protuberans COL1A1-PDGFB fusion is identified in virtually all dermatofibrosarcoma protuberans cases when investigated by newly developed multiplex reverse transcription polymerase chain reaction and fluorescence in situ hybridiz

scientific article
An experimental model for the study of well-differentiated and dedifferentiated liposarcoma; deregulation of targetable tyrosine kinase receptors

scientific article
Rad51 overexpression contributes to chemoresistance in human soft tissue sarcoma cells: a role for p53/activator protein 2 transcriptional regulation

scientific article
Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylation

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Beyond BRAF(V600): clinical mutation panel testing by next-generation sequencing in advanced melanoma

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Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas

scientific article published on 2 April 2018
The LPP1 and DPP1 gene products account for most of the isoprenoid phosphate phosphatase activities in Saccharomyces cerevisiae

scientific article
Human sebaceous tumors harbor inactivating mutations in LEF1.

scientific article published on 26 March 2006
B cells and tertiary lymphoid structures promote immunotherapy response

scientific article published on 15 January 2020
MiR-155 is a liposarcoma oncogene that targets casein kinase-1α and enhances β-catenin signaling

scientific article
Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry

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Complete response of stage IV anal mucosal melanoma expressing KIT Val560Asp to the multikinase inhibitor sorafenib

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Molecular profiling of patient-matched brain and extracranial melanoma metastases implicates the PI3K pathway as a therapeutic target

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Detection and characterization of EWSR1/ATF1 and EWSR1/CREB1 chimeric transcripts in clear cell sarcoma (melanoma of soft parts).

scientific article
Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics

scientific article published in April 2018
CTNNB1 45F mutation is a molecular prognosticator of increased postoperative primary desmoid tumor recurrence: an independent, multicenter validation study.

scientific article published on 31 July 2013
American Joint Committee on Cancer acceptance criteria for inclusion of risk models for individualized prognosis in the practice of precision medicine

scientific article published on 19 January 2016
Autophagic survival in resistance to histone deacetylase inhibitors: novel strategies to treat malignant peripheral nerve sheath tumors

scientific article published on 16 November 2010
Cross species genomic analysis identifies a mouse model as undifferentiated pleomorphic sarcoma/malignant fibrous histiocytoma

scientific article
MUC4 Is a Sensitive and Extremely Useful Marker for Sclerosing Epithelioid Fibrosarcoma

scientific article published on 01 October 2012
New perspectives for staging and prognosis in soft tissue sarcoma

scientific article published on 3 June 2008
Extensive survey of STAT6 expression in a large series of mesenchymal tumors

scientific article
Clinical characteristics and outcomes with specific BRAF and NRAS mutations in patients with metastatic melanoma

scientific article published on 6 August 2013
Complete loss of PTEN protein expression correlates with shorter time to brain metastasis and survival in stage IIIB/C melanoma patients with BRAFV600 mutations

scientific article
ROR2 is a novel prognostic biomarker and a potential therapeutic target in leiomyosarcoma and gastrointestinal stromal tumour

scientific article published on 17 February 2012
Adipophilin expression in sebaceous tumors and other cutaneous lesions with clear cell histology: an immunohistochemical study of 117 cases

scientific article
Loss of H3K27 tri-methylation is a diagnostic marker for malignant peripheral nerve sheath tumors and an indicator for an inferior survival.

scientific article published on 18 March 2016
Dual targeting of AKT and mammalian target of rapamycin: a potential therapeutic approach for malignant peripheral nerve sheath tumor

scientific article published on 5 May 2009
Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

scientific article published in April 2018
Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF).

scientific article published on 16 December 2004
Cutaneous clear cell sarcoma: a clinicopathologic, immunohistochemical, and molecular analysis of 12 cases emphasizing its distinction from dermal melanoma

scientific article published in February 2010
NKD2, a negative regulator of Wnt signaling, suppresses tumor growth and metastasis in osteosarcoma

scientific article
Localized and metastatic myxoid/round cell liposarcoma: clinical and molecular observations

scientific article published on 7 February 2013
Primary vascular tumors and tumor-like lesions of the kidney: a clinicopathologic analysis of 25 cases.

scientific article
Staging soft tissue sarcoma: evolution and change.

scientific article published on September 2006
Genetic aberrations of gastrointestinal stromal tumors

scientific article
Activated MET is a molecular prognosticator and potential therapeutic target for malignant peripheral nerve sheath tumors

scientific article
Long-term outcomes in patients with radiation-associated angiosarcomas of the breast following surgery and radiotherapy for breast cancer

scientific article published on 06 December 2012
Neoadjuvant plus adjuvant dabrafenib and trametinib versus standard of care in patients with high-risk, surgically resectable melanoma: a single-centre, open-label, randomised, phase 2 trial

scientific article
Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set.

scientific article
Locoregional disease patterns in well-differentiated and dedifferentiated retroperitoneal liposarcoma: implications for the extent of resection?

scientific article published on 7 April 2014
Hotspot mutation panel testing reveals clonal evolution in a study of 265 paired primary and metastatic tumors

scientific article published on 18 February 2015
Genetic aberrations in soft tissue leiomyosarcoma

scientific article published on 22 July 2008
Malignant peripheral nerve sheath tumour (MPNST): the clinical implications of cellular signalling pathways

scientific article published on 19 October 2009
Clinical responses to selumetinib (AZD6244; ARRY-142886)-based combination therapy stratified by gene mutations in patients with metastatic melanoma

scientific article published on 12 September 2012
Primary Cutaneous Apocrine Carcinoma

Galectin-3 Expression Is Associated with Tumor Progression and Pattern of Sun Exposure in Melanoma

scientific article published on 01 November 2006
Involvement of the PI3K/Akt pathway in myxoid/round cell liposarcoma

scientific article published on 21 October 2011
Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma.

scientific article

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