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List of works by Hans Bräuner-Osborne

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Differential compartmentalization and distinct functions of GABAB receptor variants

scientific article
Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors

scientific article published on January 2012
Agonists and inverse agonists for the herpesvirus 8-encoded constitutively active seven-transmembrane oncogene product, ORF-74

scientific article
Structure, pharmacology and therapeutic prospects of family C G-protein coupled receptors

scientific article
The agonist-binding domain of the calcium-sensing receptor is located at the amino-terminal domain

scientific article published on June 1999
Positive allosteric modulation of the human metabotropic glutamate receptor 4 (hmGluR4) by SIB-1893 and MPEP

scientific article
Molecular cloning, expression, and sequence analysis of GPRC6A, a novel family C G-protein-coupled receptor

scientific article
Specific gamma-hydroxybutyrate-binding sites but loss of pharmacological effects of gamma-hydroxybutyrate in GABA(B)(1)-deficient mice

scientific article
Molecular pharmacology of promiscuous seven transmembrane receptors sensing organic nutrients.

scientific article published on June 2009
Pharmacology of muscarinic acetylcholine receptor subtypes (m1-m5): high throughput assays in mammalian cells

scientific journal article
Different domains of the glucagon and glucagon-like peptide-1 receptors provide the critical determinants of ligand selectivity

scientific article published on March 2003
Sequence and expression pattern of a novel human orphan G-protein-coupled receptor, GPRC5B, a family C receptor with a short amino-terminal domain

scientific article
Quinazolin-4-one derivatives: A novel class of noncompetitive NR2C/D subunit-selective N-methyl-D-aspartate receptor antagonists

scientific article
Real-time trafficking and signaling of the glucagon-like peptide-1 receptor

scientific article published on 22 November 2013
Biased agonism of the calcium-sensing receptor

scientific journal article
α4βδ GABA(A) receptors are high-affinity targets for γ-hydroxybutyric acid (GHB)

scientific article
Molecular pharmacology of human NMDA receptors

scientific article published on 17 December 2011
Probing intermolecular protein-protein interactions in the calcium-sensing receptor homodimer using bioluminescence resonance energy transfer (BRET).

scientific article published on October 2002
The GABAB1a isoform mediates heterosynaptic depression at hippocampal mossy fiber synapses.

scientific article published in February 2009
The GPCR, class C, group 6, subtype A (GPRC6A) receptor: from cloning to physiological function

scientific article published on March 2014
Interactions between calcium and phosphorus in the regulation of the production of fibroblast growth factor 23 in vivo

scientific article published on 11 December 2012
Constitutive activation of muscarinic receptors by the G-protein Gq.

scientific article published on April 1995
3B but which 3B and that's just one of the questions: the heterogeneity of human 5-HT3 receptors.

scientific article
Synthesis and structure-activity relationships of N-benzyl phenethylamines as 5-HT2A/2C agonists.

scientific article
Delineation of the GPRC6A receptor signaling pathways using a mammalian cell line stably expressing the receptor

scientific article published on 5 September 2013
No evidence for a bone phenotype in GPRC6A knockout mice under normal physiological conditions

scientific article
Molecular determinants of non-competitive antagonist binding to the mouse GPRC6A receptor

scientific article published on November 2009
The rat GPRC6A: cloning and characterization

scientific article
Cloning and characterization of a human orphan family C G-protein coupled receptor GPRC5D

scientific article
Functional importance of the Ala(116)-Pro(136) region in the calcium-sensing receptor. Constitutive activity and inverse agonism in a family C G-protein-coupled receptor

scientific article published on September 2000
The anticonvulsant gabapentin (neurontin) does not act through gamma-aminobutyric acid-B receptors.

scientific article published in June 2002
(R)-(3-amino-2-fluoropropyl) phosphinic acid (AZD3355), a novel GABAB receptor agonist, inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action

scientific article published on 31 July 2009
Pharmacological characterization of human excitatory amino acid transporters EAAT1, EAAT2 and EAAT3 in a fluorescence-based membrane potential assay

scientific article published in June 2004
Cloning and characterization of a functional human gamma-aminobutyric acid (GABA) transporter, human GAT-2.

scientific article published on 14 May 2007
A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid

scientific article published on August 1996
Pharmacological characterization of ligands at recombinant NMDA receptor subtypes by electrophysiological recordings and intracellular calcium measurements

scientific article
Implementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate receptor antagonists

scientific article
The L-α-amino acid receptor GPRC6A is expressed in the islets of Langerhans but is not involved in L-arginine-induced insulin release

scientific article published on 20 June 2012
Carbamoylcholine homologs: novel and potent agonists at neuronal nicotinic acetylcholine receptors

scientific article published on October 2003
L-Arginine improves multiple physiological parameters in mice exposed to diet-induced metabolic disturbances

scientific article published on 27 December 2011
Oral L-arginine stimulates GLP-1 secretion to improve glucose tolerance in male mice

scientific article published on 19 August 2013
(S)-homo-AMPA, a specific agonist at the mGlu6 subtype of metabotropic glutamic acid receptors

scientific article published on October 1997
Homology modelling of the GABA transporter and analysis of tiagabine binding

scientific article published on July 2010
Computer-aided discovery of aromatic l-α-amino acids as agonists of the orphan G protein-coupled receptor GPR139.

scientific article published on 30 May 2014
Pharmacological characterization and modeling of the binding sites of novel 1,3-bis(pyridinylethynyl)benzenes as metabotropic glutamate receptor 5-selective negative allosteric modulators

scientific article published on 16 August 2012
Increased susceptibility to diet-induced obesity in GPRC6A receptor knockout mice

scientific article published on 15 April 2013
Ibotenic acid and thioibotenic acid: a remarkable difference in activity at group III metabotropic glutamate receptors

scientific article
Functional consequences of glucagon-like peptide-1 receptor cross-talk and trafficking

scientific article published on December 2014
Interaction of CPCCOEt with a chimeric mGlu1b and calcium sensing receptor

scientific article
Total synthesis and structure-activity relationship studies of a series of selective G protein inhibitors

scientific article published on 25 July 2016

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