List of works - Per Hoffmann

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Identification of loci associated with schizophrenia by genome-wide association and follow-up

scientific article

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

scientific article published on 26 April 2018

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.

scientific article

Direct conversion of fibroblasts into stably expandable neural stem cells

scientific article

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

scientific article

Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24.

scientific article

Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018

Disruption of the neurexin 1 gene is associated with schizophrenia

scientific article

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

scientific article

Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate

scientific article

Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci

scientific journal article

Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes

scientific article published on 11 August 2013

Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease

scientific article published on 23 November 2011

Genome-wide association study reveals two new risk loci for bipolar disorder

scientific article (publication date: 11 March 2014)

Genome-wide association study identifies 30 loci associated with bipolar disorder.

scientific article

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

scientific article

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

article

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

scientific article

Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study

scientific article published on 21 January 2016

Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster

scientific article published on 18 October 2011

Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture

scientific article

Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk

scientific journal article

Characterization of a family with rare deletions in CNTNAP5 and DOCK4 suggests novel risk loci for autism and dyslexia

scientific article

A locus on 2p12 containing the co-regulated MRPL19 and C2ORF3 genes is associated to dyslexia

scientific article

Association between genetic variation in a region on chromosome 11 and schizophrenia in large samples from Europe

scientific article

Genome-wide association study identifies multiple susceptibility loci for multiple myeloma

scientific article

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

scientific article published on February 2017

Genome-wide association study in German patients with attention deficit/hyperactivity disorder

scientific article published on 19 October 2011

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

scientific article published on 26 November 2018

The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma

scientific article

First genome-wide association scan on neurophysiological endophenotypes points to trans-regulation effects on SLC2A3 in dyslexic children

scientific article published on 29 September 2009

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

scientific article

Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts

scientific article

Analysis of 10 independent samples provides evidence for association between schizophrenia and a SNP flanking fibroblast growth factor receptor 2.

scientific article

Genome-wide association study on differentiated thyroid cancer

scientific journal article

Investigation of the DCDC2 intron 2 deletion/compound short tandem repeat polymorphism in a large German dyslexia sample

scientific article published in December 2008

Genetics of dyslexia: the evolving landscape

scientific article

The DISC locus and schizophrenia: evidence from an association study in a central European sample and from a meta-analysis across different European populations

scientific article published on 04 May 2009

Common obesity risk alleles in childhood attention-deficit/hyperactivity disorder

scientific article published on 26 March 2013

Association between schizophrenia and common variation in neurocan (NCAN), a genetic risk factor for bipolar disorder

scientific article published on 11 April 2012

Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia.

scientific article

Deep intronic APC mutations explain a substantial proportion of patients with familial or early-onset adenomatous polyposis

scientific article

Common variation at 10p12.31 near MLLT10 influences meningioma risk

scientific article

αCaMKII autophosphorylation controls the establishment of alcohol drinking behavior

scientific article published on 04 March 2013

16p11.2 600 kb Duplications confer risk for typical and atypical Rolandic epilepsy

scientific article published on 16 June 2014

Genome-wide analysis of rare copy number variations reveals PARK2 as a candidate gene for attention-deficit/hyperactivity disorder

scientific article

Investigation of interaction between DCDC2 and KIAA0319 in a large German dyslexia sample

scientific article published on 23 September 2008

Genetic analysis of dyslexia candidate genes in the European cross-linguistic NeuroDys cohort

scientific article published on 11 September 2013

List of works by Per Hoffmann

Defining the role of common variation in the genomic and biological architecture of adult human height

Identification of loci associated with schizophrenia by genome-wide association and follow-up

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.

Direct conversion of fibroblasts into stably expandable neural stem cells

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24.

Analysis of shared heritability in common disorders of the brain

Disruption of the neurexin 1 gene is associated with schizophrenia

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate

Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci

Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes

Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease

Genome-wide association study reveals two new risk loci for bipolar disorder

Genome-wide association study identifies 30 loci associated with bipolar disorder.

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study

Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster

Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture

Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk

Characterization of a family with rare deletions in CNTNAP5 and DOCK4 suggests novel risk loci for autism and dyslexia

A locus on 2p12 containing the co-regulated MRPL19 and C2ORF3 genes is associated to dyslexia

Association between genetic variation in a region on chromosome 11 and schizophrenia in large samples from Europe

Genome-wide association study identifies multiple susceptibility loci for multiple myeloma

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

Genome-wide association study in German patients with attention deficit/hyperactivity disorder

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma

First genome-wide association scan on neurophysiological endophenotypes points to trans-regulation effects on SLC2A3 in dyslexic children

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts

Analysis of 10 independent samples provides evidence for association between schizophrenia and a SNP flanking fibroblast growth factor receptor 2.

Genome-wide association study on differentiated thyroid cancer

Investigation of the DCDC2 intron 2 deletion/compound short tandem repeat polymorphism in a large German dyslexia sample

Genetics of dyslexia: the evolving landscape

The DISC locus and schizophrenia: evidence from an association study in a central European sample and from a meta-analysis across different European populations

Common obesity risk alleles in childhood attention-deficit/hyperactivity disorder

Association between schizophrenia and common variation in neurocan (NCAN), a genetic risk factor for bipolar disorder

Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia.

Deep intronic APC mutations explain a substantial proportion of patients with familial or early-onset adenomatous polyposis

Common variation at 10p12.31 near MLLT10 influences meningioma risk

αCaMKII autophosphorylation controls the establishment of alcohol drinking behavior

16p11.2 600 kb Duplications confer risk for typical and atypical Rolandic epilepsy

Genome-wide analysis of rare copy number variations reveals PARK2 as a candidate gene for attention-deficit/hyperactivity disorder

Investigation of interaction between DCDC2 and KIAA0319 in a large German dyslexia sample

Genetic analysis of dyslexia candidate genes in the European cross-linguistic NeuroDys cohort