List of works - Richard Bruggeman

Biological insights from 108 schizophrenia-associated genetic loci

scientific article

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

scientific article

Large recurrent microdeletions associated with schizophrenia

scientific article

Genome-wide association study identifies five new schizophrenia loci

scientific article

Schizophrenia risk from complex variation of complement component 4

scientific article

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

scientific article

Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

scientific article

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

scientific article

Disruption of the neurexin 1 gene is associated with schizophrenia

scientific article

Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors

scientific article

All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs

scientific article

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

article

Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder

scientific article

Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations

scientific article

Expanding the range of ZNF804A variants conferring risk of psychosis

scientific article published on 5 January 2010

Double-blind clinical trial of thalamic stimulation in patients with Tourette syndrome

scientific article published on 01 March 2011

The detection of CMV pp65 and IE1 in glioblastoma multiforme

scientific article published on 5 September 2010

Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci

scientific article

Deep brain stimulation in Tourette's syndrome: two targets?

scientific article published in May 2006

Predominant role of the 9-hydroxy metabolite of risperidone in elevating blood prolactin levels

scientific article published in May 2005

Runs of homozygosity implicate autozygosity as a schizophrenia risk factor

scientific article

Risperidone versus pimozide in Tourette's disorder: a comparative double-blind parallel-group study.

scientific article

A randomized open-label study of the impact of quetiapine versus risperidone on sexual functioning

scientific article

Neural correlates of alexithymia: a meta-analysis of emotion processing studies

scientific article published on 22 July 2013

Genome-wide analysis shows increased frequency of copy number variation deletions in Dutch schizophrenia patients

scientific article

Effects of bilateral repetitive transcranial magnetic stimulation on treatment resistant auditory-verbal hallucinations in schizophrenia: a randomized controlled trial

scientific article published on 13 August 2009

High levels of expression of human stromal cell-derived factor-1 are associated with worse prognosis in patients with stage II pancreatic ductal adenocarcinoma

scientific article published on 23 August 2010

Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: a polygenic risk score analysis

scientific article (publication date: 2012)

GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia

scientific article

Childhood abuse and neglect in relation to the presence and persistence of psychotic and depressive symptomatology

scientific article published on 17 July 2014

A systematic review of instruments to measure depressive symptoms in patients with schizophrenia

scientific article

The effects of lifestyle interventions on (long-term) weight management, cardiometabolic risk and depressive symptoms in people with psychotic disorders: a meta-analysis

scientific article

AKT1 moderation of cannabis-induced cognitive alterations in psychotic disorder

scientific article

The effectiveness of peer support groups in psychosis: a randomized controlled trial

scientific article published on 01 July 2008

When Broca goes uninformed: reduced information flow to Broca's area in schizophrenia patients with auditory hallucinations

scientific article

Estimating dopamine D₂ receptor occupancy for doses of 8 antipsychotics: a meta-analysis

scientific article published on October 2013

New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis

scientific article

A large replication study and meta-analysis in European samples provides further support for association of AHI1 markers with schizophrenia

scientific article

A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation

scientific article published on 17 July 2013

Voxel-based gray and white matter morphometry correlates of hallucinations in schizophrenia: The superior temporal gyrus does not stand alone

scientific article

Integrated pathway-based approach identifies association between genomic regions at CTCF and CACNB2 and schizophrenia

scientific article

Neural correlates of emotion regulation in patients with schizophrenia and non-affected siblings

scientific article

Treatment of negative symptoms: Where do we stand, and where do we go?

scientific article published on 9 June 2016

Tardive dyskinesia and DRD3, HTR2A and HTR2C gene polymorphisms in Russian psychiatric inpatients from Siberia

scientific article published on 24 January 2009

Reduced connectivity in the self-processing network of schizophrenia patients with poor insight

scientific article

The effect of childhood maltreatment and cannabis use on adult psychotic symptoms is modified by the COMT Val¹⁵⁸Met polymorphism

scientific article published on 15 August 2013

ABCB1 gene variants influence tolerance to selective serotonin reuptake inhibitors in a large sample of Dutch cases with major depressive disorder

scientific article published on 29 May 2012

The role of dopamine D3, 5-HT2A and 5-HT2C receptor variants as pharmacogenetic determinants in tardive dyskinesia in African-Caribbean patients under chronic antipsychotic treatment: Curacao extrapyramidal syndromes study IX.

scientific article published on 18 June 2008

COMT Val158Met polymorphism, verbalizing of emotion and activation of affective brain systems

scientific article published on 13 December 2010

Association between HTR2C gene polymorphisms and the metabolic syndrome in patients using antipsychotics: a replication study

scientific article published on 3 August 2010

List of works by Richard Bruggeman

Biological insights from 108 schizophrenia-associated genetic loci

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Large recurrent microdeletions associated with schizophrenia

Genome-wide association study identifies five new schizophrenia loci

Schizophrenia risk from complex variation of complement component 4

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Disruption of the neurexin 1 gene is associated with schizophrenia

Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors

All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder

Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations

Expanding the range of ZNF804A variants conferring risk of psychosis

Double-blind clinical trial of thalamic stimulation in patients with Tourette syndrome

The detection of CMV pp65 and IE1 in glioblastoma multiforme

Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci

Deep brain stimulation in Tourette's syndrome: two targets?

Predominant role of the 9-hydroxy metabolite of risperidone in elevating blood prolactin levels

Runs of homozygosity implicate autozygosity as a schizophrenia risk factor

Risperidone versus pimozide in Tourette's disorder: a comparative double-blind parallel-group study.

A randomized open-label study of the impact of quetiapine versus risperidone on sexual functioning

Neural correlates of alexithymia: a meta-analysis of emotion processing studies

Genome-wide analysis shows increased frequency of copy number variation deletions in Dutch schizophrenia patients

Effects of bilateral repetitive transcranial magnetic stimulation on treatment resistant auditory-verbal hallucinations in schizophrenia: a randomized controlled trial

High levels of expression of human stromal cell-derived factor-1 are associated with worse prognosis in patients with stage II pancreatic ductal adenocarcinoma

Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: a polygenic risk score analysis

GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia

Childhood abuse and neglect in relation to the presence and persistence of psychotic and depressive symptomatology

A systematic review of instruments to measure depressive symptoms in patients with schizophrenia

The effects of lifestyle interventions on (long-term) weight management, cardiometabolic risk and depressive symptoms in people with psychotic disorders: a meta-analysis

AKT1 moderation of cannabis-induced cognitive alterations in psychotic disorder

The effectiveness of peer support groups in psychosis: a randomized controlled trial

When Broca goes uninformed: reduced information flow to Broca's area in schizophrenia patients with auditory hallucinations

Estimating dopamine D₂ receptor occupancy for doses of 8 antipsychotics: a meta-analysis

New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis

A large replication study and meta-analysis in European samples provides further support for association of AHI1 markers with schizophrenia

A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation

Voxel-based gray and white matter morphometry correlates of hallucinations in schizophrenia: The superior temporal gyrus does not stand alone

Integrated pathway-based approach identifies association between genomic regions at CTCF and CACNB2 and schizophrenia

Neural correlates of emotion regulation in patients with schizophrenia and non-affected siblings

Treatment of negative symptoms: Where do we stand, and where do we go?

Tardive dyskinesia and DRD3, HTR2A and HTR2C gene polymorphisms in Russian psychiatric inpatients from Siberia

Reduced connectivity in the self-processing network of schizophrenia patients with poor insight

The effect of childhood maltreatment and cannabis use on adult psychotic symptoms is modified by the COMT Val¹⁵⁸Met polymorphism

ABCB1 gene variants influence tolerance to selective serotonin reuptake inhibitors in a large sample of Dutch cases with major depressive disorder

The role of dopamine D3, 5-HT2A and 5-HT2C receptor variants as pharmacogenetic determinants in tardive dyskinesia in African-Caribbean patients under chronic antipsychotic treatment: Curacao extrapyramidal syndromes study IX.

COMT Val158Met polymorphism, verbalizing of emotion and activation of affective brain systems

Association between HTR2C gene polymorphisms and the metabolic syndrome in patients using antipsychotics: a replication study