List of works - Peter Holmans

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

scientific article

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

scientific article

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

scientific article

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

scientific article

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

scientific article

Rare chromosomal deletions and duplications increase risk of schizophrenia

scientific article

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

scientific article (publication date: May 2011)

De novo mutations in schizophrenia implicate synaptic networks

scientific article

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

scientific article published in October 2013

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

scientific article

Identification of loci associated with schizophrenia by genome-wide association and follow-up

scientific article

Common variants on chromosome 6p22.1 are associated with schizophrenia

scientific article

De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia.

scientific article

Regional and cellular gene expression changes in human Huntington's disease brain

scientific article published on 8 February 2006

A survey of genetic human cortical gene expression

article

Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder

scientific article

Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: a genome-wide analysis

scientific article

Meta-Analysis of Genome-Wide Association Studies of Attention-Deficit/Hyperactivity Disorder

scientific article published on August 1, 2010

The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia

scientific article

Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications

scientific article

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

scientific article

Support for the involvement of large copy number variants in the pathogenesis of schizophrenia

scientific article published on 29 January 2009

Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

scientific article

Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk

scientific article

Susceptibility locus for Alzheimer's disease on chromosome 10.

scientific article

A full genome scan for late onset Alzheimer's disease

scientific article published in February 1999

Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia

scientific article

Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease

scientific article (publication date: 15 November 2010)

Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia

scientific article

Most genome-wide significant susceptibility loci for schizophrenia and bipolar disorder reported to date cross-traditional diagnostic boundaries

scientific article published on 29 October 2010

Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder

scientific article published on 06 April 2010

Genetic control of human brain transcript expression in Alzheimer disease

scientific article published on April 2009

Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies

scientific article (publication date: February 2011)

Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants

article

Genome-wide association study identifies 30 loci associated with bipolar disorder.

scientific article

Genome-wide association study of recurrent early-onset major depressive disorder

scientific journal article

Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC.

scientific article

Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders.

scientific article

Meta-analysis of 32 genome-wide linkage studies of schizophrenia.

scientific article published on 30 December 2008

Genome-wide analysis of copy number variants in attention deficit hyperactivity disorder: the role of rare variants and duplications at 15q13.3.

scientific article published on February 2012

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration

scientific article

Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease

article

Investigating the contribution of common genetic variants to the risk and pathogenesis of ADHD.

scientific article published on February 2012

A combined analysis of D22S278 marker alleles in affected sib-pairs: support for a susceptibility locus for schizophrenia at chromosome 22q12. Schizophrenia Collaborative Linkage Group (Chromosome 22).

scientific article published on February 1996

A family based association study of T102C polymorphism in 5HT2A and schizophrenia plus identification of new polymorphisms in the promoter.

scientific article published on January 1998

Rare copy number variants: a point of rarity in genetic risk for bipolar disorder and schizophrenia

scientific article published on April 2010

Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease

scientific article published on 13 August 2012

Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations

scientific article

List of works by Peter Holmans

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Rare chromosomal deletions and duplications increase risk of schizophrenia

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

De novo mutations in schizophrenia implicate synaptic networks

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

Identification of loci associated with schizophrenia by genome-wide association and follow-up

Common variants on chromosome 6p22.1 are associated with schizophrenia

De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia.

Regional and cellular gene expression changes in human Huntington's disease brain

A survey of genetic human cortical gene expression

Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder

Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: a genome-wide analysis

Meta-Analysis of Genome-Wide Association Studies of Attention-Deficit/Hyperactivity Disorder

The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia

Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Support for the involvement of large copy number variants in the pathogenesis of schizophrenia

Analysis of shared heritability in common disorders of the brain

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk

Susceptibility locus for Alzheimer's disease on chromosome 10.

A full genome scan for late onset Alzheimer's disease

Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia

Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease

Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia

Most genome-wide significant susceptibility loci for schizophrenia and bipolar disorder reported to date cross-traditional diagnostic boundaries

Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder

Genetic control of human brain transcript expression in Alzheimer disease

Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies

Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants

Genome-wide association study identifies 30 loci associated with bipolar disorder.

Genome-wide association study of recurrent early-onset major depressive disorder

Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC.

Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders.

Meta-analysis of 32 genome-wide linkage studies of schizophrenia.

Genome-wide analysis of copy number variants in attention deficit hyperactivity disorder: the role of rare variants and duplications at 15q13.3.

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration

Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease

Investigating the contribution of common genetic variants to the risk and pathogenesis of ADHD.

A combined analysis of D22S278 marker alleles in affected sib-pairs: support for a susceptibility locus for schizophrenia at chromosome 22q12. Schizophrenia Collaborative Linkage Group (Chromosome 22).

A family based association study of T102C polymorphism in 5HT2A and schizophrenia plus identification of new polymorphisms in the promoter.

Rare copy number variants: a point of rarity in genetic risk for bipolar disorder and schizophrenia

Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease

Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations