List of works - Lynne J Hocking

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Common genetic determinants of vitamin D insufficiency: a genome-wide association study

scientific article

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

scientific article

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

scientific article

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

scientific article

Genome-wide association study identifies 74 loci associated with educational attainment

scientific article published on 11 May 2016

Rheumatoid arthritis association at 6q23.

scientific article

Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk

scientific article

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Bone remodelling at a glance

scientific article published on 01 April 2011

Domain-specific mutations in sequestosome 1 (SQSTM1) cause familial and sporadic Paget's disease

scientific article published on 01 October 2002

Cohort Profile: Generation Scotland: Scottish Family Health Study (GS:SFHS). The study, its participants and their potential for genetic research on health and illness.

scientific article

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

scientific article published in November 2015

Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13.

scientific article published on 14 September 2008

Re-evaluation of putative rheumatoid arthritis susceptibility genes in the post-genome wide association study era and hypothesis of a key pathway underlying susceptibility

scientific article published on 22 April 2008

Molecular genetic contributions to socioeconomic status and intelligence.

scientific article

KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

scientific article

Directional dominance on stature and cognition in diverse human populations

scientific article published in July 2015

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

scientific article

Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus

scientific article

Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region

scientific article

Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium

scientific article published on 24 May 2016

Autophagy: a new player in skeletal maintenance?

scientific article published in July 2012

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

scientific article

Multi-ethnic genome-wide association study for atrial fibrillation

article

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 27 April 2017

Novel UBA domain mutations of SQSTM1 in Paget's disease of bone: genotype phenotype correlation, functional analysis, and structural consequences

scientific article published on 22 March 2004

Identification of AF4/FMR2 family, member 3 (AFF3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-autoimmune susceptibility genes

scientific article published on 09 April 2009

Loss of Ubiquitin-Binding Associated With Paget's Disease of Bone p62 (SQSTM1) Mutations

article

Overlapping genetic susceptibility variants between three autoimmune disorders: rheumatoid arthritis, type 1 diabetes and coeliac disease

scientific article

Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23.

scientific article published on 05 May 2009

Genetic variation in the beta2-adrenergic receptor but not catecholamine-O-methyltransferase predisposes to chronic pain: Results from the 1958 British Birth Cohort Study

Informed conditioning on clinical covariates increases power in case-control association studies

scientific article published on 8 November 2012

Reevaluation of the interaction between HLA-DRB1 shared epitope alleles, PTPN22, and smoking in determining susceptibility to autoantibody-positive and autoantibody-negative rheumatoid arthritis in a large UK Caucasian population

scientific article published on September 2009

Evaluation of the role of RANK and OPG genes in Paget's disease of bone

scientific article published on January 2001

GWAS for executive function and processing speed suggests involvement of the CADM2 gene.

scientific article

Polymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal women

scientific article

Association of CD40 with rheumatoid arthritis confirmed in a large UK case-control study

scientific article

Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

scientific article

Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants

scientific article

Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease

scientific article published on 21 December 2015

PADI4 genotype is not associated with rheumatoid arthritis in a large UK Caucasian population

scientific article

Nitric oxide is a mediator of apoptosis in the rheumatoid joint

scientific article published on 01 September 2000

Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study

scientific article

Genetics and aetiology of Pagetic disorders of bone

scientific article published on 10 March 2008

Mutation Screening of the TNFRSF11A Gene Encoding Receptor Activator of NFkB (RANK) in Familial and Sporadic Paget's Disease of Bone and Osteosarcoma

article

Predicting the risk of rheumatoid arthritis and its age of onset through modelling genetic risk variants with smoking

scientific article

Susceptibility to Paget's disease of bone is influenced by a common polymorphic variant of osteoprotegerin

scientific article

Familial Paget’s disease of bone: patterns of inheritance and frequency of linkage to chromosome 18q

scientific article published on 01 June 2000

Cardiovascular risk factors associated with the metabolic syndrome are more prevalent in people reporting chronic pain: Results from a cross-sectional general population study

scientific article published on 07 May 2013

List of works by Lynne J Hocking

Guidelines for the use and interpretation of assays for monitoring autophagy

Common genetic determinants of vitamin D insufficiency: a genome-wide association study

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

Genome-wide association study identifies 74 loci associated with educational attainment

Rheumatoid arthritis association at 6q23.

Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk

Rare and low-frequency coding variants alter human adult height

Bone remodelling at a glance

Domain-specific mutations in sequestosome 1 (SQSTM1) cause familial and sporadic Paget's disease

Cohort Profile: Generation Scotland: Scottish Family Health Study (GS:SFHS). The study, its participants and their potential for genetic research on health and illness.

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13.

Re-evaluation of putative rheumatoid arthritis susceptibility genes in the post-genome wide association study era and hypothesis of a key pathway underlying susceptibility

Molecular genetic contributions to socioeconomic status and intelligence.

KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

Directional dominance on stature and cognition in diverse human populations

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus

Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region

Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium

Autophagy: a new player in skeletal maintenance?

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

Multi-ethnic genome-wide association study for atrial fibrillation

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

Novel UBA domain mutations of SQSTM1 in Paget's disease of bone: genotype phenotype correlation, functional analysis, and structural consequences

Identification of AF4/FMR2 family, member 3 (AFF3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-autoimmune susceptibility genes

Loss of Ubiquitin-Binding Associated With Paget's Disease of Bone p62 (SQSTM1) Mutations

Overlapping genetic susceptibility variants between three autoimmune disorders: rheumatoid arthritis, type 1 diabetes and coeliac disease

Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23.

Genetic variation in the beta2-adrenergic receptor but not catecholamine-O-methyltransferase predisposes to chronic pain: Results from the 1958 British Birth Cohort Study

Informed conditioning on clinical covariates increases power in case-control association studies

Reevaluation of the interaction between HLA-DRB1 shared epitope alleles, PTPN22, and smoking in determining susceptibility to autoantibody-positive and autoantibody-negative rheumatoid arthritis in a large UK Caucasian population

Evaluation of the role of RANK and OPG genes in Paget's disease of bone

GWAS for executive function and processing speed suggests involvement of the CADM2 gene.

Polymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal women

Association of CD40 with rheumatoid arthritis confirmed in a large UK case-control study

Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants

Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease

PADI4 genotype is not associated with rheumatoid arthritis in a large UK Caucasian population

Nitric oxide is a mediator of apoptosis in the rheumatoid joint

Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study

Genetics and aetiology of Pagetic disorders of bone

Mutation Screening of the TNFRSF11A Gene Encoding Receptor Activator of NFkB (RANK) in Familial and Sporadic Paget's Disease of Bone and Osteosarcoma

Predicting the risk of rheumatoid arthritis and its age of onset through modelling genetic risk variants with smoking

Susceptibility to Paget's disease of bone is influenced by a common polymorphic variant of osteoprotegerin

Familial Paget’s disease of bone: patterns of inheritance and frequency of linkage to chromosome 18q

Cardiovascular risk factors associated with the metabolic syndrome are more prevalent in people reporting chronic pain: Results from a cross-sectional general population study