List of works - Lasse Folkersen

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Large-scale association analysis identifies new risk loci for coronary artery disease

scientific article published on 02 December 2012

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

scientific article

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

scientific article

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

scientific article

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

CD49a Expression Defines Tissue-Resident CD8+ T Cells Poised for Cytotoxic Function in Human Skin

scientific article

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

scientific journal article

Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1

scientific article

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease

scientific article (publication date: 17 September 2013)

Relationship between CAD risk genotype in the chromosome 9p21 locus and gene expression. Identification of eight new ANRIL splice variants

scientific article

Dickkopf-1 Enhances Inflammatory Interaction Between Platelets and Endothelial Cells and Shows Increased Expression in Atherosclerosis

Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism

scientific article

Association of genetic risk variants with expression of proximal genes identifies novel susceptibility genes for cardiovascular disease

scientific article

Interleukin-6 receptor pathways in abdominal aortic aneurysm

scientific article published on 30 October 2012

NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis

scientific article published on 20 May 2016

Toll-Like Receptor 7 Protects From Atherosclerosis by Constraining “Inflammatory” Macrophage Activation

scientific article published on 11 July 2012

Unraveling divergent gene expression profiles in bicuspid and tricuspid aortic valve patients with thoracic aortic dilatation: the ASAP study

scientific article published on 27 September 2011

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation

scientific article

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci

scientific article

Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study

scientific article published on 31 July 2013

Gene expression signatures, pathways and networks in carotid atherosclerosis

article

Profiling of atherosclerotic lesions by gene and tissue microarrays reveals PCSK6 as a novel protease in unstable carotid atherosclerosis

scientific article published in August 2013

Expression of fatty acid-binding protein 4/aP2 is correlated with plaque instability in carotid atherosclerosis

12- and 15-lipoxygenases in human carotid atherosclerotic lesions: associations with cerebrovascular symptoms

scientific article published on 21 January 2011

Impaired splicing of fibronectin is associated with thoracic aortic aneurysm formation in patients with bicuspid aortic valve

scientific article

Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis

scientific article

Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-media thickness and coronary artery disease risk

scientific article

Chemokine expression in retinal pigment epithelial ARPE-19 cells in response to coculture with activated T cells

scientific article

Prediction of ischemic events on the basis of transcriptomic and genomic profiling in patients undergoing carotid endarterectomy

scientific article

Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease

scientific article

Increased expression of heparanase in symptomatic carotid atherosclerosis

Association of TERC and OBFC1 haplotypes with mean leukocyte telomere length and risk for coronary heart disease

scientific article published on 12 December 2013

High plasma adiponectin concentration is associated with all-cause mortality in patients with carotid atherosclerosis

scientific article published on 8 October 2012

Functional Analysis of a Novel Genome-Wide Association Study Signal in SMAD3 That Confers Protection From Coronary Artery Disease.

scientific article published on 10 March 2016

A Genome-Wide Association Study Identifies KNG1 as a Genetic Determinant of Plasma Factor XI Level and Activated Partial Thromboplastin Time

article by Maria Sabater-Lleal et al published August 2012 in Arteriosclerosis, Thrombosis, and Vascular Biology

The chromosome 9p21.3 coronary heart disease risk allele is associated with altered gene expression in normal heart and vascular tissues

scientific article

Matrix metalloproteinase 14 and 19 expression is associated with thoracic aortic aneurysms.

scientific article

Correlations between clinical variables and gene-expression profiles in carotid plaque instability

scientific article

Protein-altering and regulatory genetic variants near GATA4 implicated in bicuspid aortic valve

scientific article

Common genetic determinants of lung function, subclinical atherosclerosis and risk of coronary artery disease

scientific article

CARD8 gene encoding a protein of innate immunity is expressed in human atherosclerosis and associated with markers of inflammation.

scientific article published in October 2013

Network-based analysis of genome wide association data provides novel candidate genes for lipid and lipoprotein traits

scientific article

Use of allele-specific FAIRE to determine functional regulatory polymorphism using large-scale genotyping arrays

scientific article

The expression of IGFs and IGF binding proteins in human carotid atherosclerosis, and the possible role of IGF binding protein-1 in the regulation of smooth muscle cell proliferation

scientific article

Tissue factor pathway inhibitor-2 is induced by fluid shear stress in vascular smooth muscle cells and affects cell proliferation and survival

scientific journal article

GLP-1 Induces Barrier Protective Expression in Brunner's Glands and Regulates Colonic Inflammation.

scientific article published on September 2016

Human mediastinal adipose tissue displays certain characteristics of brown fat.

scientific article published on 13 May 2013

List of works by Lasse Folkersen

Genetic studies of body mass index yield new insights for obesity biology

Defining the role of common variation in the genomic and biological architecture of adult human height

Large-scale association analysis identifies new risk loci for coronary artery disease

New genetic loci link adipose and insulin biology to body fat distribution

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

CD49a Expression Defines Tissue-Resident CD8+ T Cells Poised for Cytotoxic Function in Human Skin

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease

Relationship between CAD risk genotype in the chromosome 9p21 locus and gene expression. Identification of eight new ANRIL splice variants

Dickkopf-1 Enhances Inflammatory Interaction Between Platelets and Endothelial Cells and Shows Increased Expression in Atherosclerosis

Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism

Association of genetic risk variants with expression of proximal genes identifies novel susceptibility genes for cardiovascular disease

Interleukin-6 receptor pathways in abdominal aortic aneurysm

NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis

Toll-Like Receptor 7 Protects From Atherosclerosis by Constraining “Inflammatory” Macrophage Activation

Unraveling divergent gene expression profiles in bicuspid and tricuspid aortic valve patients with thoracic aortic dilatation: the ASAP study

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci

Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study

Gene expression signatures, pathways and networks in carotid atherosclerosis

Profiling of atherosclerotic lesions by gene and tissue microarrays reveals PCSK6 as a novel protease in unstable carotid atherosclerosis

Expression of fatty acid-binding protein 4/aP2 is correlated with plaque instability in carotid atherosclerosis

12- and 15-lipoxygenases in human carotid atherosclerotic lesions: associations with cerebrovascular symptoms

Impaired splicing of fibronectin is associated with thoracic aortic aneurysm formation in patients with bicuspid aortic valve

Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis

Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-media thickness and coronary artery disease risk

Chemokine expression in retinal pigment epithelial ARPE-19 cells in response to coculture with activated T cells

Prediction of ischemic events on the basis of transcriptomic and genomic profiling in patients undergoing carotid endarterectomy

Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease

Increased expression of heparanase in symptomatic carotid atherosclerosis

Association of TERC and OBFC1 haplotypes with mean leukocyte telomere length and risk for coronary heart disease

High plasma adiponectin concentration is associated with all-cause mortality in patients with carotid atherosclerosis

Functional Analysis of a Novel Genome-Wide Association Study Signal in SMAD3 That Confers Protection From Coronary Artery Disease.

A Genome-Wide Association Study Identifies KNG1 as a Genetic Determinant of Plasma Factor XI Level and Activated Partial Thromboplastin Time

The chromosome 9p21.3 coronary heart disease risk allele is associated with altered gene expression in normal heart and vascular tissues

Matrix metalloproteinase 14 and 19 expression is associated with thoracic aortic aneurysms.

Correlations between clinical variables and gene-expression profiles in carotid plaque instability

Protein-altering and regulatory genetic variants near GATA4 implicated in bicuspid aortic valve

Common genetic determinants of lung function, subclinical atherosclerosis and risk of coronary artery disease

CARD8 gene encoding a protein of innate immunity is expressed in human atherosclerosis and associated with markers of inflammation.

Network-based analysis of genome wide association data provides novel candidate genes for lipid and lipoprotein traits

Use of allele-specific FAIRE to determine functional regulatory polymorphism using large-scale genotyping arrays

The expression of IGFs and IGF binding proteins in human carotid atherosclerosis, and the possible role of IGF binding protein-1 in the regulation of smooth muscle cell proliferation

Tissue factor pathway inhibitor-2 is induced by fluid shear stress in vascular smooth muscle cells and affects cell proliferation and survival

GLP-1 Induces Barrier Protective Expression in Brunner's Glands and Regulates Colonic Inflammation.

Human mediastinal adipose tissue displays certain characteristics of brown fat.