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List of works by Liesbeth Vandenput

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Genetic studies of body mass index yield new insights for obesity biology

scientific article
Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article
Common genetic determinants of vitamin D insufficiency: a genome-wide association study

scientific article
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

scientific article
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article
New genetic loci link adipose and insulin biology to body fat distribution

scientific article
Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts

scientific article (publication date: 2013)
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article
Androgens and Bone

Quality control and conduct of genome-wide association meta-analyses

scientific article
Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture

scientific article
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

scientific article published on 26 June 2011
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

scientific article published on 14 April 2013
Older men with low serum estradiol and high serum SHBG have an increased risk of fractures

scientific article published in October 2008
WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk

scientific article published in July 2012
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article
Sex steroid actions in male bone

scientific article
Genetic determinants of serum testosterone concentrations in men.

scientific article
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

scientific article published on February 2016
High serum testosterone is associated with reduced risk of cardiovascular events in elderly men. The MrOS (Osteoporotic Fractures in Men) study in Sweden

scientific article published on October 2011
Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus

scientific article
Low serum testosterone and estradiol predict mortality in elderly men.

scientific article published on 28 April 2009
Measurement of a Comprehensive Sex Steroid Profile in Rodent Serum by High-Sensitive Gas Chromatography-Tandem Mass Spectrometry

scientific article published on 9 April 2015
A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation

scientific article
Estrogens as regulators of bone health in men.

scientific article published on 16 June 2009
Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure

scientific article
Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

scientific article published on 17 January 2018
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

scientific article
Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 27 April 2017
Comparable amounts of sex steroids are made outside the gonads in men and women: strong lesson for hormone therapy of prostate and breast cancer

scientific article
SHBGGene Promoter Polymorphisms in Men Are Associated with Serum Sex Hormone-Binding Globulin, Androgen and Androgen Metabolite Levels, and Hip Bone Mineral Density

scientific article published on 22 August 2006
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

scientific article published on February 2016
Evidence for geographical and racial variation in serum sex steroid levels in older men.

scientific article
Genome-wide association meta-analysis of cortical bone mineral density unravels allelic heterogeneity at the RANKL locus and potential pleiotropic effects on bone

scientific article
Older men with low serum IGF-1 have an increased risk of incident fractures: the MrOS Sweden study

scientific article published in April 2011
Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

scientific article
Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms

scientific article
Testosterone but not estradiol level is positively related to muscle strength and physical performance independent of muscle mass: a cross-sectional study in 1489 older men

scholarly article by Tung Wai Auyeung et al published May 2011 in European Journal of Endocrinology
Evidence from the aged orchidectomized male rat model that 17beta-estradiol is a more effective bone-sparing and anabolic agent than 5alpha-dihydrotestosterone

scientific journal article
The Uridine Diphosphate Glucuronosyltransferase 2B15 D85Y and 2B17 Deletion Polymorphisms Predict the Glucuronidation Pattern of Androgens and Fat Mass in Men

Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits

scientific article published on 21 June 2016
Multi-ethnic fine-mapping of 14 central adiposity loci

scientific article
Genetic evidence of assortative mating in humans

scholarly article
Skeletal effects of estrogen deficiency as induced by an aromatase inhibitor in an aged male rat model

article
Genetic variations in sex steroid-related genes as predictors of serum estrogen levels in men.

scientific article published on 30 December 2008
Serum levels of specific glucuronidated androgen metabolites predict BMD and prostate volume in elderly men.

scientific article published on February 2007
The role of estrogens for male bone health

scientific article published on 20 March 2009
Assessment of gene-by-sex interaction effect on bone mineral density

scientific article (publication date: October 2012)
Testosterone prevents orchidectomy-induced bone loss in estrogen receptor-alpha knockout mice

scientific article published in July 2001
Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis

scientific article

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