List of works - Sonia Levi

The human counterpart of zebrafish shiraz shows sideroblastic-like microcytic anemia and iron overload.

scientific article

A human mitochondrial ferritin encoded by an intronless gene

scientific journal article

Overexpression of wild type and mutated human ferritin H-chain in HeLa cells: in vivo role of ferritin ferroxidase activity.

scientific article

Structure, function, and evolution of ferritins.

scientific article

Early embryonic lethality of H ferritin gene deletion in mice

scientific article published in February 2000

Cytosolic and mitochondrial ferritins in the regulation of cellular iron homeostasis and oxidative damage

scientific article published on 20 February 2010

Identification of the ferroxidase centre in ferritin

scientific article published on 01 August 1989

Mitochondrial ferritin expression in erythroid cells from patients with sideroblastic anemia

scientific article

Mitochondrial ferritin limits oxidative damage regulating mitochondrial iron availability: hypothesis for a protective role in Friedreich ataxia

scientific article

RNA silencing of the mitochondrial ABCB7 transporter in HeLa cells causes an iron-deficient phenotype with mitochondrial iron overload

scientific article published on 27 December 2006

The dentate nucleus in Friedreich's ataxia: the role of iron-responsive proteins

scientific article

The Role of the L-Chain in Ferritin Iron Incorporation

scientific article published on 01 May 1994

Neurodegeneration with brain iron accumulation: update on pathogenic mechanisms

scientific article published in 2014

Mitochondrial ferritin expression in adult mouse tissues

scientific article published on 11 July 2007

Flow cytometry evaluation of erythroid dysplasia in patients with myelodysplastic syndrome

scientific article published in April 2006

Analysis of the biologic functions of H- and L-ferritins in HeLa cells by transfection with siRNAs and cDNAs: evidence for a proliferative role of L-ferritin

scientific article published on 13 November 2003

Human mitochondrial ferritin expressed in HeLa cells incorporates iron and affects cellular iron metabolism

scientific article published on 12 April 2002

The expression of human mitochondrial ferritin rescues respiratory function in frataxin-deficient yeast

scientific article published on 28 July 2004

Mitochondrial ferritin.

scientific article published on October 2004

Multiple mechanisms of iron-induced ferritin synthesis in HeLa cells

scientific article published in 1985

Defective targeting of hemojuvelin to plasma membrane is a common pathogenetic mechanism in juvenile hemochromatosis

scientific article published on 30 January 2007

Immunochemical characterization of human liver and heart ferritins with monoclonal antibodies.

scientific article

Crystal structure and biochemical properties of the human mitochondrial ferritin and its mutant Ser144Ala

scientific article

Oxidative stress and cell death in cells expressing L-ferritin variants causing neuroferritinopathy

scientific article published on 23 September 2009

Genetic hyperferritinaemia and reticuloendothelial iron overload associated with a three base pair deletion in the coding region of the ferroportin gene (SLC11A3).

scientific article published in November 2002

Multiple Pathways for Mineral Core Formation in Mammalian Apoferritin. The Role of Hydrogen Peroxide†

scientific article published on 01 March 2003

Overexpression of the hereditary hemochromatosis protein, HFE, in HeLa cells induces an iron-deficient phenotype

scientific article published on 01 October 1999

The pathogenesis of cardiomyopathy in Friedreich ataxia.

scientific article

Pantothenate kinase-associated neurodegeneration: altered mitochondria membrane potential and defective respiration in Pank2 knock-out mouse model

scientific journal article

Influence of site-directed modifications on the formation of iron cores in ferritin

scientific article published on 01 October 1991

Mutant ferritin L-chains that cause neurodegeneration act in a dominant-negative manner to reduce ferritin iron incorporation

scientific article

Functional and Immunological Analysis of Recombinant Mouse H- and L-Ferritins from Escherichia coli

scientific article published on 01 June 2000

Reconstitution of manganese oxide cores in horse spleen and recombinant ferritins.

scientific article published in April 1995

Functional roles of the ferritin receptors of human liver, hepatoma, lymphoid and erythroid cells

scientific article published on August 1992

Role of iron and ferritin in TNFalpha-induced apoptosis in HeLa cells

scientific article published in February 2003

Mitochondrial iron and energetic dysfunction distinguish fibroblasts and induced neurons from pantothenate kinase-associated neurodegeneration patients

scientific article published on 30 March 2015

Relationship between TNF-alpha and iron metabolism in differentiating human monocytic THP-1 cells.

scientific article

Role of intracellular labile iron, ferritin, and antioxidant defence in resistance of chronically adapted Jurkat T cells to hydrogen peroxide

scientific article

Skin fibroblasts from pantothenate kinase-associated neurodegeneration patients show altered cellular oxidative status and have defective iron-handling properties.

scientific article

Over-expression of mitochondrial ferritin affects the JAK2/STAT5 pathway in K562 cells and causes mitochondrial iron accumulation

scientific article

Neuroferritinopathy: From ferritin structure modification to pathogenetic mechanism

scientific article

Iron detoxifying activity of ferritin

scientific article published on 01 December 1990

Characterization of human ferritin H chain synthetized in Escherichia coli

scientific article

Human L-ferritin deficiency is characterized by idiopathic generalized seizures and atypical restless leg syndrome.

scientific article published on 12 August 2013

Microelectronic DNA chip for hereditary hyperferritinemia cataract syndrome, a model for large-scale analysis of disorders of iron metabolism.

scientific article published in February 2006

A novel neuroferritinopathy mouse model (FTL 498InsTC) shows progressive brain iron dysregulation, morphological signs of early neurodegeneration and motor coordination deficits.

scientific article

A new mutation (G51C) in the iron-responsive element (IRE) of l-ferritin associated with hyperferritinaemia-cataract syndrome decreases the binding affinity of the mutated IRE for iron-regulatory proteins

scientific article published on 01 March 2000

Development of an immunoassay for all human isoferritins, and its application to serum ferritin evaluation

scientific article published on October 1989

Iron availability is increased in individual human ovarian follicles in close proximity to an endometrioma compared with distal ones

scientific article published on 15 January 2014

Characterization of the l-ferritin variant 460InsA responsible of a hereditary ferritinopathy disorder

scientific article published on 05 July 2006

List of works by Sonia Levi

The human counterpart of zebrafish shiraz shows sideroblastic-like microcytic anemia and iron overload.

A human mitochondrial ferritin encoded by an intronless gene

Overexpression of wild type and mutated human ferritin H-chain in HeLa cells: in vivo role of ferritin ferroxidase activity.

Structure, function, and evolution of ferritins.

Early embryonic lethality of H ferritin gene deletion in mice

Cytosolic and mitochondrial ferritins in the regulation of cellular iron homeostasis and oxidative damage

Identification of the ferroxidase centre in ferritin

Mitochondrial ferritin expression in erythroid cells from patients with sideroblastic anemia

Mitochondrial ferritin limits oxidative damage regulating mitochondrial iron availability: hypothesis for a protective role in Friedreich ataxia

RNA silencing of the mitochondrial ABCB7 transporter in HeLa cells causes an iron-deficient phenotype with mitochondrial iron overload

The dentate nucleus in Friedreich's ataxia: the role of iron-responsive proteins

The Role of the L-Chain in Ferritin Iron Incorporation

Neurodegeneration with brain iron accumulation: update on pathogenic mechanisms

Mitochondrial ferritin expression in adult mouse tissues

Flow cytometry evaluation of erythroid dysplasia in patients with myelodysplastic syndrome

Analysis of the biologic functions of H- and L-ferritins in HeLa cells by transfection with siRNAs and cDNAs: evidence for a proliferative role of L-ferritin

Human mitochondrial ferritin expressed in HeLa cells incorporates iron and affects cellular iron metabolism

The expression of human mitochondrial ferritin rescues respiratory function in frataxin-deficient yeast

Mitochondrial ferritin.

Multiple mechanisms of iron-induced ferritin synthesis in HeLa cells

Defective targeting of hemojuvelin to plasma membrane is a common pathogenetic mechanism in juvenile hemochromatosis

Immunochemical characterization of human liver and heart ferritins with monoclonal antibodies.

Crystal structure and biochemical properties of the human mitochondrial ferritin and its mutant Ser144Ala

Oxidative stress and cell death in cells expressing L-ferritin variants causing neuroferritinopathy

Genetic hyperferritinaemia and reticuloendothelial iron overload associated with a three base pair deletion in the coding region of the ferroportin gene (SLC11A3).

Multiple Pathways for Mineral Core Formation in Mammalian Apoferritin. The Role of Hydrogen Peroxide†

Overexpression of the hereditary hemochromatosis protein, HFE, in HeLa cells induces an iron-deficient phenotype

The pathogenesis of cardiomyopathy in Friedreich ataxia.

Pantothenate kinase-associated neurodegeneration: altered mitochondria membrane potential and defective respiration in Pank2 knock-out mouse model

Influence of site-directed modifications on the formation of iron cores in ferritin

Mutant ferritin L-chains that cause neurodegeneration act in a dominant-negative manner to reduce ferritin iron incorporation

Functional and Immunological Analysis of Recombinant Mouse H- and L-Ferritins from Escherichia coli

Reconstitution of manganese oxide cores in horse spleen and recombinant ferritins.

Functional roles of the ferritin receptors of human liver, hepatoma, lymphoid and erythroid cells

Role of iron and ferritin in TNFalpha-induced apoptosis in HeLa cells

Mitochondrial iron and energetic dysfunction distinguish fibroblasts and induced neurons from pantothenate kinase-associated neurodegeneration patients

Relationship between TNF-alpha and iron metabolism in differentiating human monocytic THP-1 cells.

Role of intracellular labile iron, ferritin, and antioxidant defence in resistance of chronically adapted Jurkat T cells to hydrogen peroxide

Skin fibroblasts from pantothenate kinase-associated neurodegeneration patients show altered cellular oxidative status and have defective iron-handling properties.

Over-expression of mitochondrial ferritin affects the JAK2/STAT5 pathway in K562 cells and causes mitochondrial iron accumulation

Neuroferritinopathy: From ferritin structure modification to pathogenetic mechanism

Iron detoxifying activity of ferritin

Characterization of human ferritin H chain synthetized in Escherichia coli

Human L-ferritin deficiency is characterized by idiopathic generalized seizures and atypical restless leg syndrome.

Microelectronic DNA chip for hereditary hyperferritinemia cataract syndrome, a model for large-scale analysis of disorders of iron metabolism.

A novel neuroferritinopathy mouse model (FTL 498InsTC) shows progressive brain iron dysregulation, morphological signs of early neurodegeneration and motor coordination deficits.

A new mutation (G51C) in the iron-responsive element (IRE) of l-ferritin associated with hyperferritinaemia-cataract syndrome decreases the binding affinity of the mutated IRE for iron-regulatory proteins

Development of an immunoassay for all human isoferritins, and its application to serum ferritin evaluation

Iron availability is increased in individual human ovarian follicles in close proximity to an endometrioma compared with distal ones

Characterization of the l-ferritin variant 460InsA responsible of a hereditary ferritinopathy disorder