List of works - Thilo Dörk

Genome-wide association study identifies novel breast cancer susceptibility loci

scientific article published on 28 June 2007

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

scientific article

Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies

scientific article

A common coding variant in CASP8 is associated with breast cancer risk

article

Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.

scientific article published on 29 March 2009

Identification of seven new prostate cancer susceptibility loci through a genome-wide association study

scientific article

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

scientific article published on April 2013

Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping

scientific article

Genome-wide association studies identify four ER negative-specific breast cancer risk loci

scientific article published in April 2013

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

scientific article

Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics

scientific article

Association analysis identifies 65 new breast cancer risk loci

scientific article published on 23 October 2017

A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.

scientific article published on 19 September 2010

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

scientific article published on April 2013

Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study

scientific article

A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2.

scientific article

Prediction of breast cancer risk based on profiling with common genetic variants

scientific article published on 8 April 2015

Genome-wide association analysis identifies three new breast cancer susceptibility loci

scientific article published on 22 January 2012

Common variants at 19p13 are associated with susceptibility to ovarian cancer

scientific article

A new type of mutation causes a splicing defect in ATM.

scientific article published on 11 March 2002

Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers

scientific article published on 27 March 2013

Human RAD50 deficiency in a Nijmegen breakage syndrome-like disorder

scientific article published on 30 April 2009

Identification of six new susceptibility loci for invasive epithelial ovarian cancer

scientific article published on 12 January 2015

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium

scientific article

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

scientific article published in November 2015

Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer

scientific article published on 27 August 2015

Multiple novel prostate cancer predisposition loci confirmed by an international study: the PRACTICAL Consortium

scientific article

Characterization of ATM gene mutations in 66 ataxia telangiectasia families.

scientific article

Testis-specific protein, Y-encoded (TSPY) expression in testicular tissues

scientific article

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer

scientific article published in 2013

A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease

scientific article

Nonclassical splicing mutations in the coding and noncoding regions of the ATM Gene: maximum entropy estimates of splice junction strengths

scientific article published on January 2004

Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk

scientific article published on 27 March 2013

Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.

scientific article published on January 2013

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

scientific article published on 23 October 2017

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

scientific article

Missense mutations but not allelic variants alter the function of ATM by dominant interference in patients with breast cancer

scientific article

Nijmegen Breakage Syndrome mutations and risk of breast cancer

scientific article published in February 2008

CHEK2*1100delC heterozygosity in women with breast cancer associated with early death, breast cancer-specific death, and increased risk of a second breast cancer

scientific article

Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation

scientific article

Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.

scientific article

Association of ESR1 gene tagging SNPs with breast cancer risk

scientific article published on 06 January 2009

The role of genetic breast cancer susceptibility variants as prognostic factors

scientific article

Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types

scientific article published in September 2016

Distinct spectrum of CFTR gene mutations in congenital absence of vas deferens

article

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

scientific article published in December 2016

Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: findings from the Breast Cancer Association Consortium

scientific article published on 18 August 2011

Do MDM2 SNP309 and TP53 R72P interact in breast cancer susceptibility? A large pooled series from the breast cancer association consortium

scientific article

Characterization of a novel 21-kb deletion, CFTRdele2,3(21 kb), in the CFTR gene: a cystic fibrosis mutation of Slavic origin common in Central and East Europe.

scientific article

Immaturity, perinatal inflammation, and retinopathy of prematurity: A multi-hit hypothesis

scientific article published on 13 February 2009

List of works by Thilo Dörk

Genome-wide association study identifies novel breast cancer susceptibility loci

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies

A common coding variant in CASP8 is associated with breast cancer risk

Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.

Identification of seven new prostate cancer susceptibility loci through a genome-wide association study

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping

Genome-wide association studies identify four ER negative-specific breast cancer risk loci

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics

Association analysis identifies 65 new breast cancer risk loci

A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study

A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2.

Prediction of breast cancer risk based on profiling with common genetic variants

Genome-wide association analysis identifies three new breast cancer susceptibility loci

Common variants at 19p13 are associated with susceptibility to ovarian cancer

A new type of mutation causes a splicing defect in ATM.

Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers

Human RAD50 deficiency in a Nijmegen breakage syndrome-like disorder

Identification of six new susceptibility loci for invasive epithelial ovarian cancer

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer

Multiple novel prostate cancer predisposition loci confirmed by an international study: the PRACTICAL Consortium

Characterization of ATM gene mutations in 66 ataxia telangiectasia families.

Testis-specific protein, Y-encoded (TSPY) expression in testicular tissues

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer

A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease

Nonclassical splicing mutations in the coding and noncoding regions of the ATM Gene: maximum entropy estimates of splice junction strengths

Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk

Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

Missense mutations but not allelic variants alter the function of ATM by dominant interference in patients with breast cancer

Nijmegen Breakage Syndrome mutations and risk of breast cancer

CHEK2*1100delC heterozygosity in women with breast cancer associated with early death, breast cancer-specific death, and increased risk of a second breast cancer

Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation

Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.

Association of ESR1 gene tagging SNPs with breast cancer risk

The role of genetic breast cancer susceptibility variants as prognostic factors

Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types

Distinct spectrum of CFTR gene mutations in congenital absence of vas deferens

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: findings from the Breast Cancer Association Consortium

Do MDM2 SNP309 and TP53 R72P interact in breast cancer susceptibility? A large pooled series from the breast cancer association consortium

Characterization of a novel 21-kb deletion, CFTRdele2,3(21 kb), in the CFTR gene: a cystic fibrosis mutation of Slavic origin common in Central and East Europe.

Immaturity, perinatal inflammation, and retinopathy of prematurity: A multi-hit hypothesis