List of works - Richard Wooster

Mutations of the BRAF gene in human cancer

scientific article (publication date: 27 June 2002)

Patterns of somatic mutation in human cancer genomes

scientific article (publication date: 8 March 2007)

A census of human cancer genes

scientific article

Identification of the breast cancer susceptibility gene BRCA2

scientific article (publication date: December 1995)

Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13.

scientific article

The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website

scientific article

Lung cancer: intragenic ERBB2 kinase mutations in tumours

scientific article

A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation

scientific article

Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.

scientific article

COSMIC 2005

scientific article

Somatic mutations of the protein kinase gene family in human lung cancer

scientific article published on September 2005

A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer

scientific article published on 22 May 2005

High-resolution analysis of DNA copy number using oligonucleotide microarrays

scientific article published on February 2004

RNA editing of human microRNAs

scientific article published on 4 April 2006

A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy

scientific article

A survey of RNA editing in human brain

scientific article

Breast and ovarian cancer

scientific article

Instability of short tandem repeats (microsatellites) in human cancers.

scientific article

Whole genome DNA copy number changes identified by high density oligonucleotide arrays

scientific article

BRCA2 mutations in primary breast and ovarian cancers

scientific article

Cancer Risks in Two Large Breast Cancer Families Linked to BRCA2 on Chromosome 13q12‐13

scientific article published on July 1, 1997

Inhibition of tumor cell growth, invasion, and metastasis by EXEL-2880 (XL880, GSK1363089), a novel inhibitor of HGF and VEGF receptor tyrosine kinases

scientific article

Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, hypogonadism, pes cavus, and tremor

scientific article

Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation

scientific article

Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution

scientific article

Kaposi's sarcoma-associated herpesvirus-infected primary effusion lymphoma has a plasma cell gene expression profile

scientific article published on 18 August 2003

Amplification and overexpression of E2F3 in human bladder cancer

scientific article published on February 2004

A germline mutation in the androgen receptor gene in two brothers with breast cancer and Reifenstein syndrome

scientific article (publication date: October 1992)

Mutations in the DLG3 gene cause nonsyndromic X-linked mental retardation

scientific article

Statistical analysis of pathogenicity of somatic mutations in cancer

scientific article

Mutations in FRMD7, a newly identified member of the FERM family, cause X-linked idiopathic congenital nystagmus

scientific article

Consistent loss of the wild type allele in breast cancers from a family linked to the BRCA2 gene on chromosome 13q12-13.

scientific article

Mutations in ZDHHC9, which encodes a palmitoyltransferase of NRAS and HRAS, cause X-linked mental retardation associated with a Marfanoid habitus

scientific article

The BRC repeats are conserved in mammalian BRCA2 proteins

scientific article

Molecular target class is predictive of in vitro response profile

scientific article published on 20 April 2010

Familial male breast cancer is not linked to the BRCA1 locus on chromosome 17q.

scientific article

Comprehensive Predictive Biomarker Analysis for MEK Inhibitor GSK1120212

scientific article published on December 14, 2011

The V617F JAK2 mutation is uncommon in cancers and in myeloid malignancies other than the classic myeloproliferative disorders

scientific article

Mutations in the gene encoding the Sigma 2 subunit of the adaptor protein 1 complex, AP1S2, cause X-linked mental retardation

scientific article

A genome wide linkage search for breast cancer susceptibility genes

scientific article published on July 2006

Genome-wide screening for complete genetic loss in prostate cancer by comparative hybridization onto cDNA microarrays

scientific article published on February 2003

Cancer and genomics

scientific article

Sensitivity of cancer cells to Plk1 inhibitor GSK461364A is associated with loss of p53 function and chromosome instability

scientific article published on 22 June 2010

Sequence variants of the axin gene in breast, colon, and other cancers: an analysis of mutations that interfere with GSK3 binding

scientific article published in August 2000

A survey of homozygous deletions in human cancer genomes

scientific article

Absence of methylation of CpG dinucleotides within the promoter of the breast cancer susceptibility gene BRCA2 in normal tissues and in breast and ovarian cancers

scientific article published on January 1, 1997

Familial cylindromatosis (turban tumour syndrome) gene localised to chromosome 16q12-q13: evidence for its role as a tumour suppressor gene

scientific article

Sequence analysis of the protein kinase gene family in human testicular germ-cell tumors of adolescents and adults

scientific article

Identification of amplified and expressed genes in breast cancer by comparative hybridization onto microarrays of randomly selected cDNA clones

scientific article

Mutations in the BRWD3 gene cause X-linked mental retardation associated with macrocephaly

scientific article

List of works by Richard Wooster

Mutations of the BRAF gene in human cancer

Patterns of somatic mutation in human cancer genomes

A census of human cancer genes

Identification of the breast cancer susceptibility gene BRCA2

Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13.

The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website

Lung cancer: intragenic ERBB2 kinase mutations in tumours

A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation

Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.

COSMIC 2005

Somatic mutations of the protein kinase gene family in human lung cancer

A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer

High-resolution analysis of DNA copy number using oligonucleotide microarrays

RNA editing of human microRNAs

A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy

A survey of RNA editing in human brain

Breast and ovarian cancer

Instability of short tandem repeats (microsatellites) in human cancers.

Whole genome DNA copy number changes identified by high density oligonucleotide arrays

BRCA2 mutations in primary breast and ovarian cancers

Cancer Risks in Two Large Breast Cancer Families Linked to BRCA2 on Chromosome 13q12‐13

Inhibition of tumor cell growth, invasion, and metastasis by EXEL-2880 (XL880, GSK1363089), a novel inhibitor of HGF and VEGF receptor tyrosine kinases

Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, hypogonadism, pes cavus, and tremor

Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation

Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution

Kaposi's sarcoma-associated herpesvirus-infected primary effusion lymphoma has a plasma cell gene expression profile

Amplification and overexpression of E2F3 in human bladder cancer

A germline mutation in the androgen receptor gene in two brothers with breast cancer and Reifenstein syndrome

Mutations in the DLG3 gene cause nonsyndromic X-linked mental retardation

Statistical analysis of pathogenicity of somatic mutations in cancer

Mutations in FRMD7, a newly identified member of the FERM family, cause X-linked idiopathic congenital nystagmus

Consistent loss of the wild type allele in breast cancers from a family linked to the BRCA2 gene on chromosome 13q12-13.

Mutations in ZDHHC9, which encodes a palmitoyltransferase of NRAS and HRAS, cause X-linked mental retardation associated with a Marfanoid habitus

The BRC repeats are conserved in mammalian BRCA2 proteins

Molecular target class is predictive of in vitro response profile

Familial male breast cancer is not linked to the BRCA1 locus on chromosome 17q.

Comprehensive Predictive Biomarker Analysis for MEK Inhibitor GSK1120212

The V617F JAK2 mutation is uncommon in cancers and in myeloid malignancies other than the classic myeloproliferative disorders

Mutations in the gene encoding the Sigma 2 subunit of the adaptor protein 1 complex, AP1S2, cause X-linked mental retardation

A genome wide linkage search for breast cancer susceptibility genes

Genome-wide screening for complete genetic loss in prostate cancer by comparative hybridization onto cDNA microarrays

Cancer and genomics

Sensitivity of cancer cells to Plk1 inhibitor GSK461364A is associated with loss of p53 function and chromosome instability

Sequence variants of the axin gene in breast, colon, and other cancers: an analysis of mutations that interfere with GSK3 binding

A survey of homozygous deletions in human cancer genomes

Absence of methylation of CpG dinucleotides within the promoter of the breast cancer susceptibility gene BRCA2 in normal tissues and in breast and ovarian cancers

Familial cylindromatosis (turban tumour syndrome) gene localised to chromosome 16q12-q13: evidence for its role as a tumour suppressor gene

Sequence analysis of the protein kinase gene family in human testicular germ-cell tumors of adolescents and adults

Identification of amplified and expressed genes in breast cancer by comparative hybridization onto microarrays of randomly selected cDNA clones

Mutations in the BRWD3 gene cause X-linked mental retardation associated with macrocephaly