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List of works by Hagop S. Akiskal

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The long-term natural history of the weekly symptomatic status of bipolar I disorder

scientific article
Lifetime and 12-month prevalence of bipolar spectrum disorder in the National Comorbidity Survey replication

scientific article
A prospective investigation of the natural history of the long-term weekly symptomatic status of bipolar II disorder

scientific article published in March 2003
Prevalence and effects of mood disorders on work performance in a nationally representative sample of U.S. workers

scientific article published in September 2006
The prevalence and disability of bipolar spectrum disorders in the US population: re-analysis of the ECA database taking into account subthreshold cases

scientific article
Psychosocial Disability in the Course of Bipolar I and II Disorders

scientific article
The International Society for Bipolar Disorders (ISBD) task force report on antidepressant use in bipolar disorders

scientific article
The comparative clinical phenotype and long term longitudinal episode course of bipolar I and II: a clinical spectrum or distinct disorders?

scientific article published in January 2003
Long-term symptomatic status of bipolar I vs. bipolar II disorders

scientific article published in June 2003
Agitated "unipolar" depression re-conceptualized as a depressive mixed state: implications for the antidepressant-suicide controversy

scientific article published in April 2005
Psychosocial disability and work role function compared across the long-term course of bipolar I, bipolar II and unipolar major depressive disorders

scientific article
TEMPS-A: progress towards validation of a self-rated clinical version of the Temperament Evaluation of the Memphis, Pisa, Paris, and San Diego Autoquestionnaire

scientific article published on March 2005
The prevalence, clinical relevance, and public health significance of subthreshold depressions

scientific article
Can temperament identify affectively ill patients who engage in lethal or near-lethal suicidal behavior? A 14-year prospective study

scientific article
Residual symptom recovery from major affective episodes in bipolar disorders and rapid episode relapse/recurrence

scientific article
Refining the evaluation of bipolar II: beyond the strict SCID-CV guidelines for hypomania

scientific article published in January 2003
Association of the s allele of the 5-HTTLPR with neuroticism-related traits and temperaments in a psychiatrically healthy population

scientific article published on 19 September 2008
Family history validation of the bipolar nature of depressive mixed states

scientific article published in January 2003
TEMPS-A: validation of a short version of a self-rated instrument designed to measure variations in temperament

scientific article published in March 2005
The role of cyclothymia in atypical depression: toward a data-based reconceptualization of the borderline-bipolar II connection

scientific article
Current research on affective temperaments

scientific article published on January 2010
Do antidepressants t(h)reat(en) depressives? Toward a clinically judicious formulation of the antidepressant-suicidality FDA advisory in light of declining national suicide statistics from many countries

scientific article
Atypical depression: a variant of bipolar II or a bridge between unipolar and bipolar II?

scientific article published in February 2005
Validity of the assessment of bipolar spectrum disorders in the WHO CIDI 3.0.

scientific article published on 25 September 2006
Depressive comorbidity of panic, social phobic, and obsessive–compulsive disorders re-examined: is there a bipolar ii connection?

scientific article (publication date: 1999)
The soft bipolar spectrum redefined: focus on the cyclothymic, anxious-sensitive, impulse-dyscontrol, and binge-eating connection in bipolar II and related conditions

scientific article
The theoretical underpinnings of affective temperaments: implications for evolutionary foundations of bipolar disorder and human nature

scientific article
Issues for DSM-5: whither melancholia? The case for its classification as a distinct mood disorder

scientific article published on July 2010
Comorbidity of bipolar and eating disorders: distinct or related disorders with shared dysregulations?

scientific article
Risk factors for depression in the survivors of the 1988 earthquake in Armenia

scientific article
Validating 'hard' and 'soft' phenotypes within the bipolar spectrum: continuity or discontinuity?

scientific article published in January 2003
Familiality of temperament in bipolar disorder: support for a genetic spectrum

scientific article
Overt irritability/anger in unipolar major depressive episodes: past and current characteristics and implications for long-term course

scientific article
Validating antidepressant-associated hypomania (bipolar III): a systematic comparison with spontaneous hypomania (bipolar II).

scientific article
TEMPS: Temperament Evaluation of Memphis, Pisa, Paris and San Diego

scientific article published in March 2005
Bipolar II with and without cyclothymic temperament: "dark" and "sunny" expressions of soft bipolarity

scientific article published on 01 January 2003
Factor structure of hypomania: interrelationships with cyclothymia and the soft bipolar spectrum

scientific article published in January 2003
Toward an integrative model of the spectrum of mood, behavioral and personality disorders based on fear and anger traits: I. Clinical implications

scientific article (publication date: August 2006)
Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis.

scientific article
Prevalence and clinical significance of subsyndromal manic symptoms, including irritability and psychomotor agitation, during bipolar major depressive episodes

scientific article published on 6 February 2012
Obsessive-compulsive bipolar comorbidity: focus on children and adolescents

scientific article published in March 2004
Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci

scientific article
Affective temperaments as measured by TEMPS-A in patients with bipolar I disorder and their first-degree relatives: a controlled study

scientific article published in March 2005
The distinct temperament profiles of bipolar I, bipolar II and unipolar patients

scientific article published on 25 April 2006
Depressive episodes and symptoms dominate the longitudinal course of bipolar disorder

scientific article published on December 1, 2003
Affective temperaments in clinically-well subjects in Turkey: initial psychometric data on the TEMPS-A.

scientific article
The 5HTTLPR polymorphism of the serotonin transporter gene is associated with affective temperaments as measured by TEMPS-A.

scientific article published on 7 February 2006
Toward a unitary perspective on the bipolar spectrum and substance abuse: opiate addiction as a paradigm

scientific article
The association between oxytocin receptor gene (OXTR) polymorphisms and affective temperaments, as measured by TEMPS-A.

scientific article published on 21 May 2010
Obsessive-compulsive-bipolar comorbidity: a systematic exploration of clinical features and treatment outcome.

scientific article published in December 2002

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