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List of works by Michael Sendtner

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A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

scientific article
Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study

scientific article
Inactivation of the survival motor neuron gene, a candidate gene for human spinal muscular atrophy, leads to massive cell death in early mouse embryos

scientific article published on September 2, 1997
The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(-/-) mice and results in a mouse with spinal muscular atrophy

scientific article published in February 2000
Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy

scientific article published in May 1990
Smn, the spinal muscular atrophy-determining gene product, modulates axon growth and localization of beta-actin mRNA in growth cones of motoneurons

scientific journal article
The Notch target genes Hey1 and Hey2 are required for embryonic vascular development

scientific journal article
Disruption of the CNTF gene results in motor neuron degeneration

scientific article published in September 1993
Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section

scientific article published in December 1992
Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis

scientific article published on November 1, 2011
Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor

scientific journal article
Na(+)-D-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion

scientific article published on 28 November 2011
Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy

scientific article (publication date: 6 August 1992)
Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines

scientific article
Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis

scientific article (publication date: May 2014)
Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons?

scientific article (publication date: 2002)
Evidence that embryonic neurons regulate the onset of cortical gliogenesis via cardiotrophin-1.

scientific article published in October 2005
Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approaches

scientific article
Global deprivation of brain-derived neurotrophic factor in the CNS reveals an area-specific requirement for dendritic growth

scientific article published in February 2010
CNTF is a major protective factor in demyelinating CNS disease: A neurotrophic cytokine as modulator in neuroinflammation

scientific article published on 01 June 2002
Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration

scientific article published on July 1, 1992
Essential function of LIF receptor in motor neurons

scientific article published in Nature
Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development

scientific journal article
Gene disruption discloses role of selenoprotein P in selenium delivery to target tissues

scientific article published on March 2003
Ciliary neurotrophic factor

scientific article
Ciliary neurotrophic factor induces type-2 astrocyte differentiation in culture

scientific article published in September 1988
Regional distribution, developmental changes, and cellular localization of CNTF-mRNA and protein in the rat brain

scientific article published in October 1991
Mutations in the gene encoding immunoglobulin mu-binding protein 2 cause spinal muscular atrophy with respiratory distress type 1

scientific article (publication date: September 2001)
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

scientific article published on 25 July 2016
A phase I/II trial of recombinant methionyl human brain derived neurotrophic factor administered by intrathecal infusion to patients with amyotrophic lateral sclerosis

scientific article published in June 2000
Members of several gene families influence survival of rat motoneurons in vitro and in vivo

scientific article published in December 1993
Does oligodendrocyte survival depend on axons?

scientific article
Developmental requirement of gp130 signaling in neuronal survival and astrocyte differentiation

scientific article
ras p21 protein promotes survival and fiber outgrowth of cultured embryonic neurons

scientific article published in January 1989
Cryptic physiological trophic support of motoneurons by LIF revealed by double gene targeting of CNTF and LIF

article
Defective Ca2+ channel clustering in axon terminals disturbs excitability in motoneurons in spinal muscular atrophy

scientific article
Proliferation and differentiation of embryonic chick sympathetic neurons: effects of ciliary neurotrophic factor

scientific article published in March 1989
Clinical characteristics of patients with familial amyotrophic lateral sclerosis carrying the pathogenic GGGGCC hexanucleotide repeat expansion of C9ORF72.

scientific article published on March 2012
Expression of neurotrophins in skeletal muscle: Quantitative comparison and significance for motoneuron survival and maintenance of function

scientific article published on 01 September 1995
Intraocular gene transfer of ciliary neurotrophic factor prevents death and increases responsiveness of rod photoreceptors in the retinal degeneration slow mouse

article
Functional role of brain-derived neurotrophic factor in neuroprotective autoimmunity: therapeutic implications in a model of multiple sclerosis

scientific article
Conditional gene ablation of Stat3 reveals differential signaling requirements for survival of motoneurons during development and after nerve injury in the adult

scientific article published on 21 January 2002
Ribosomal deficiencies in Diamond-Blackfan anemia impair translation of transcripts essential for differentiation of murine and human erythroblasts

scientific article
Type-2 astrocyte development in rat brain cultures is initiated by a CNTF like protein produced by type-1 astrocytes

scientific article published on 01 August 1988
Reduced survival motor neuron (Smn) gene dose in mice leads to motor neuron degeneration: an animal model for spinal muscular atrophy type III

article
A transgene carrying an A2G missense mutation in the SMN gene modulates phenotypic severity in mice with severe (type I) spinal muscular atrophy.

scientific article
The CB1 cannabinoid receptor mediates excitotoxicity-induced neural progenitor proliferation and neurogenesis

scientific article
PTEN depletion rescues axonal growth defect and improves survival in SMN-deficient motor neurons

scientific article published on 4 June 2010
Ciliary neurotrophic factor enhances the rate of oligodendrocyte generation

scientific article published in January 1996
Can physical exercise in old age improve memory and hippocampal function?

scientific article published on February 11, 2016

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