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List of works by John Whittaker

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An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people

scientific article published on 17 May 2012
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

scientific article published on 14 March 2012
The support of human genetic evidence for approved drug indications

scientific article published on 29 June 2015
Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts

scientific article (publication date: 2013)
Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease.

scientific article published on 13 February 2005
Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data

scientific article (publication date: 15 February 2011)
Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

scientific article
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

scientific article published on 24 September 2014
Simultaneous analysis of all SNPs in genome-wide and re-sequencing association studies

scientific article
Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials

scientific article
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci

scientific article
Polymorphism at the C-reactive protein locus influences gene expression and predisposes to systemic lupus erythematosus

scientific article
Genome-wide association study of major recurrent depression in the U.K. population

scientific article published in June 2010
Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study

scientific article published on 22 February 2013
Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

scientific article
Genome-wide significance for dense SNP and resequencing data

scientific article
Marker-assisted selection using ridge regression

article
Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus

scientific article published on 02 December 2007
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip

scientific article
HLA-DQA1*02:01 is a major risk factor for lapatinib-induced hepatotoxicity in women with advanced breast cancer

scientific article published on 18 January 2011
Pazopanib efficacy in renal cell carcinoma: evidence for predictive genetic markers in angiogenesis-related and exposure-related genes.

scientific article
Functional variants of the central bile acid sensor FXR identified in intrahepatic cholestasis of pregnancy

scientific article published on 23 May 2007
Evidence for an Interaction Between Familial Liability and Prenatal Exposure to Infection in the Causation of Schizophrenia

article
Fine-scale mapping of disease loci via shattered coalescent modeling of genealogies.

scientific article published on 08 February 2002
Limits to causal inference based on Mendelian randomization: a comparison with randomized controlled trials

scientific article
Sequence-level population simulations over large genomic regions

scientific article published on 18 October 2007
Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966

scientific article
Blood pressure loci identified with a gene-centric array

scientific article
Genetic risk factors for variant Creutzfeldt-Jakob disease: a genome-wide association study

scientific article published on January 2009
Analysis of multiple SNPs in a candidate gene or region

scientific article
Potential impact of adding genetic markers to clinical parameters in predicting prostate biopsy outcomes in men following an initial negative biopsy: findings from the REDUCE trial

scientific article published on 12 May 2012
A Novel Protective Prion Protein Variant that Colocalizes with Kuru Exposure

scientific article
Bayesian fine-scale mapping of disease loci, by hidden Markov models.

scientific article published on June 2000
Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: systematic review and meta-analysis of 14,015 stroke cases and pooled analysis of primary biomarker data from up to 60,883 individuals

scientific article
Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin D

scientific article (publication date: 2012)
The role and interaction of imprinted genes in human fetal growth

scientific article
Genetics of ischaemic stroke among persons of non-European descent: a meta-analysis of eight genes involving approximately 32,500 individuals

scientific article published in April 2007
A Bayesian toolkit for genetic association studies

scientific article published in April 2006
Little loss of information due to unknown phase for fine-scale linkage-disequilibrium mapping with single-nucleotide-polymorphism genotype data.

scientific article
Fregene: simulation of realistic sequence-level data in populations and ascertained samples

scientific article
Fine mapping of disease genes via haplotype clustering.

scientific article published in February 2006
Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP

scientific journal article
Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis

scientific article published on 15 January 2016
Refinement of variant selection for the LDL cholesterol genetic risk score in the diagnosis of the polygenic form of clinical familial hypercholesterolemia and replication in samples from 6 countries

scientific article published on 20 November 2014
Sixty-five common genetic variants and prediction of type 2 diabetes

scientific article published on 4 December 2014
Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration

scientific article published on 30 July 2011
Bayesian meta-analysis of genetic association studies with different sets of markers

scientific article published on April 2008
The clonal evolution of metastases from primary serous epithelial ovarian cancers

scientific article published in April 2009
Performance of genotype imputation for rare variants identified in exons and flanking regions of genes

scientific article (publication date: 2011)
Evidence for both copy number and allelic (NA1/NA2) risk at the FCGR3B locus in systemic lupus erythematosus

scientific article published on 5 May 2010

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