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List of works by Alexander Schleiffer

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Systematic analysis of human protein complexes identifies chromosome segregation proteins

scientific article
Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication

scientific article
Wapl controls the dynamic association of cohesin with chromatin

scientific article
Sororin mediates sister chromatid cohesion by antagonizing Wapl

scientific article
A screen for genes required for meiosis and spore formation based on whole-genome expression.

scientific article
Functional genomics identifies monopolin: a kinetochore protein required for segregation of homologs during meiosis i.

scientific article
A Caenorhabditis elegans cohesion protein with functions in meiotic chromosome pairing and disjunction

scientific article
Kinetochore recruitment of two nucleolar proteins is required for homolog segregation in meiosis I.

scientific article
Eco1 is a novel acetyltransferase that can acetylate proteins involved in cohesion

scientific article
Forkhead-like transcription factors recruit Ndd1 to the chromatin of G2/M-specific promoters

scientific article
Human Scc4 is required for cohesin binding to chromatin, sister-chromatid cohesion, and mitotic progression

scientific article
HSPC117 is the essential subunit of a human tRNA splicing ligase complex

scientific article
Sister chromatid separation and chromosome re-duplication are regulated by different mechanisms in response to spindle damage

scientific article published on May 1999
Kleisins: a superfamily of bacterial and eukaryotic SMC protein partners

scientific article
CENP-T proteins are conserved centromere receptors of the Ndc80 complex

scientific article
Switching transcription on and off during the yeast cell cycle: Cln/Cdc28 kinases activate bound transcription factor SBF (Swi4/Swi6) at start, whereas Clb/Cdc28 kinases displace it from the promoter in G2.

scientific article
Two fission yeast homologs of Drosophila Mei-S332 are required for chromosome segregation during meiosis I and II.

scientific article published in February 2004
Mitotic activation of the kinase Aurora-A requires its binding partner Bora

scientific article published on August 2006
A structural basis for kinetochore recruitment of the Ndc80 complex via two distinct centromere receptors

scientific article
Mammalian inscuteable regulates spindle orientation and cell fate in the developing retina

scientific article published on November 2005
Characterization of the DOC1/APC10 subunit of the yeast and the human anaphase-promoting complex

scientific article
The kinetochore proteins Pcs1 and Mde4 and heterochromatin are required to prevent merotelic orientation

scientific article published on July 2007
Augmenting β-augmentation: structural basis of how BamB binds BamA and may support folding of outer membrane proteins

scientific article
Arabidopsis SMG7 protein is required for exit from meiosis.

scientific article
Analysis of orthologous groups reveals archease and DDX1 as tRNA splicing factors

scientific article
Family matters: structural and functional conservation of centromere-associated proteins from yeast to humans

scientific article published on 05 March 2013
Diversity and roles of (t)RNA ligases

scientific article published on 17 March 2012
Molecular processes during fat cell development revealed by gene expression profiling and functional annotation

scientific article
A cooperative mechanism drives budding yeast kinetochore assembly downstream of CENP-A.

scientific article
Combinatorial activation and repression by seven transcription factors specify Drosophila odorant receptor expression

scientific article
A REC8-dependent plant Shugoshin is required for maintenance of centromeric cohesion during meiosis and has no mitotic functions

scientific article published in May 2005
MYRbase: analysis of genome-wide glycine myristoylation enlarges the functional spectrum of eukaryotic myristoylated proteins

scientific article
The transmembrane protein Golden goal regulates R8 photoreceptor axon-axon and axon-target interactions

scientific article
ANNIE: integrated de novo protein sequence annotation

scientific article published on 23 April 2009
The Drosophila meiotic kleisin C(2)M functions before the meiotic divisions

scientific article published on 30 July 2004
Laser microsurgery provides evidence for merotelic kinetochore attachments in fission yeast cells lacking Pcs1 or Clr4.

scientific article
High-throughput knockout screen in fission yeast

scientific article published on January 2006
From a single double helix to paired double helices and back

scientific article
GMI1, a structural-maintenance-of-chromosomes-hinge domain-containing protein, is involved in somatic homologous recombination in Arabidopsis

scientific article
Structural basis for the disaggregase activity and regulation of Hsp104.

scientific article published on 30 November 2016
Role of the RNA/DNA kinase Grc3 in transcription termination by RNA polymerase I

scientific article
Topology and structure of an engineered human cohesin complex bound to Pds5B.

scientific article
Deep and precise quantification of the mouse synaptosomal proteome reveals substantial remodeling during postnatal maturation

scientific article published on 22 September 2014
Linear ubiquitination by LUBEL has a role in Drosophila heat stress response.

scientific article published on 04 October 2016
Inhibitory effect of TIS7 on Sp1-C/EBPalpha transcription factor module activity

scientific article published in February 2004
The Ly6/uPAR protein Bouncer is necessary and sufficient for species-specific fertilization

scientific article
Mouse ANKRD31 Regulates Spatiotemporal Patterning of Meiotic Recombination Initiation and Ensures Recombination between X and Y Sex Chromosomes

scientific article published on 15 April 2019
DOUTfinder--identification of distant domain outliers using subsignificant sequence similarity

scientific article
Endosome and Golgi-associated degradation (EGAD) of membrane proteins regulates sphingolipid metabolism

scientific article published on 27 May 2019
Multilayered VBC score predicts sgRNAs that efficiently generate loss-of-function alleles

scientific article published on 08 June 2020

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