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List of works by Claudio Franceschi

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Strikingly higher frequency in centenarians and twins of mtDNA mutation causing remodeling of replication origin in leukocytes

scientific article
CD45 isoforms expression on CD4+ and CD8+ T cells throughout life, from newborns to centenarians: implications for T cell memory

scientific article published in March 1996
Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study

scientific article published on 06 February 2013
Circulating mitochondrial DNA increases with age and is a familiar trait: Implications for “inflamm-aging”

scientific article published on 13 February 2014
Functional metagenomic profiling of intestinal microbiome in extreme ageing

scientific article published on December 1, 2013
Marked increase with age of type 1 cytokines within memory and effector/cytotoxic CD8+ T cells in humans: a contribution to understand the relationship between inflammation and immunosenescence

scientific article published in September 2003
Age-related inflammation: the contribution of different organs, tissues and systems. How to face it for therapeutic approaches.

scientific article published on January 2010
Inflammation, genetics, and longevity: further studies on the protective effects in men of IL-10 -1082 promoter SNP and its interaction with TNF-alpha -308 promoter SNP.

scientific article published in April 2003
Apoptosis, DNA damage and ubiquitin expression in normal and mdx muscle fibers after exercise

scientific article published on October 16, 1995
Metabolic signatures of extreme longevity in northern Italian centenarians reveal a complex remodeling of lipids, amino acids, and gut microbiota metabolism

scientific article
What accounts for the wide variation in life span of genetically identical organisms reared in a constant environment?

scientific article
Do men and women follow different trajectories to reach extreme longevity? Italian Multicenter Study on Centenarians (IMUSCE).

scientific article published in April 2000
Interleukin-6 gene alleles affect the risk of Alzheimer's disease and levels of the cytokine in blood and brain

scientific article published in November 2003
Fibroblast cultures from healthy centenarians have an active proteasome

scientific article published on 01 September 2000
New advances in CMV and immunosenescence

scientific article
HAPLOFIND: a new method for high-throughput mtDNA haplogroup assignment

scientific article published on 12 June 2013
Identification of a geographic area characterized by extreme longevity in the Sardinia island: the AKEA study

scientific article
Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia

scientific journal article
Evidence for sub-haplogroup h5 of mitochondrial DNA as a risk factor for late onset Alzheimer's disease

scientific article
The genetics of human longevity

scientific article published on May 2006
The Continuum of Aging and Age-Related Diseases: Common Mechanisms but Different Rates

scientific article published on 12 March 2018
Chemokines, sTNF-Rs and sCD30 serum levels in healthy aged people and centenarians

scientific article published on 01 December 2000
MARK-AGE biomarkers of ageing

scientific article
The A3 adenosine receptor mediates cell spreading, reorganization of actin cytoskeleton, and distribution of Bcl-XL: studies in human astroglioma cells.

scientific article published in December 1997
Lipoprotein(a) and lipoprotein profile in healthy centenarians: a reappraisal of vascular risk factors

scientific article published on 01 April 1998
Increased brain-predicted aging in treated HIV disease

scientific article
Novel loci and pathways significantly associated with longevity

scientific article published on 25 February 2016
Intense Antiextracellular Adaptive Immune Response to Human Cytomegalovirus in Very Old Subjects with Impaired Health and Cognitive and Functional Status

scientific article published on February 19, 2010
Genetics of healthy aging in Europe: the EU-integrated project GEHA (GEnetics of Healthy Aging).

scientific article published on April 2007
Immune system, cell senescence, aging and longevity--inflamm-aging reappraised

scientific article published on January 2013
Different contribution of EBV and CMV infections in very long-term carriers to age-related alterations of CD8+ T cells

scientific article published on 01 August 2004
Gender, aging and longevity in humans: an update of an intriguing/neglected scenario paving the way to a gender-specific medicine

scientific article
Identifying the genomic determinants of aging and longevity in human population studies: progress and challenges

scientific article published on 19 February 2013
Diverse effect of inflammatory markers on insulin resistance and insulin-resistance syndrome in the elderly

scientific article published in March 2004
Biomarkers of immunosenescence within an evolutionary perspective: the challenge of heterogeneity and the role of antigenic load

scientific article (publication date: December 1999)
Thymic hormone deficiency in normal ageing and Down's syndrome: is there a primary failure of the thymus?

scientific article published on 01 May 1984
Combating inflammaging through a Mediterranean whole diet approach: the NU-AGE project's conceptual framework and design

scientific article published on 14 December 2013
Mitochondria, aging and longevity--a new perspective.

scientific article
Health relevance of the modification of low grade inflammation in ageing (inflammageing) and the role of nutrition

scientific article published on 9 September 2017
Age- and glycemia-related miR-126-3p levels in plasma and endothelial cells.

scientific article
Association between the interleukin-1beta polymorphisms and Alzheimer's disease: a systematic review and meta-analysis

scientific article published on 21 July 2008
Gene polymorphisms predicting high plasma levels of coagulation and fibrinolysis proteins. A study in centenarians.

scientific article
Leukocyte telomere length is associated with complications of Type 2 diabetes mellitus

scientific article published on 01 November 2011
Immunogenetics, gender, and longevity.

scientific article published on November 2006
Chronic inflammation in the etiology of disease across the life span

scientific article published on 05 December 2019
Human intestinal microbiota: cross-talk with the host and its potential role in colorectal cancer

scientific article published on 29 September 2010
Long-term immune-endocrine effects of bereavement: relationships with anxiety levels and mood

scientific article
Age-dependent alteration in muscle regeneration: the critical role of tissue niche

scientific article published on 12 May 2013
Identification of a DNA methylation signature in blood cells from persons with Down Syndrome

scientific article
Serum N-glycan profile shift during human ageing

scientific article

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