List of works - Janice Holton

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

scientific article (publication date: May 2008)

Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease

scientific article

A common LRRK2 mutation in idiopathic Parkinson's disease

scientific article published on 29 January 2005

Lewy- and Alzheimer-type pathologies in Parkinson's disease dementia: which is more important?

scientific article

Characteristics of two distinct clinical phenotypes in pathologically proven progressive supranuclear palsy: Richardson's syndrome and PSP-parkinsonism

scientific article

PINK1 protein in normal human brain and Parkinson's disease

scientific article

A clinico-pathological study of subtypes in Parkinson's disease

scientific article published on 16 September 2009

Neuropathology underlying clinical variability in patients with synucleinopathies

scientific article published on July 2011

SNCA variants are associated with increased risk for multiple system atrophy

scientific article

The spectrum of pathological involvement of the striatonigral and olivopontocerebellar systems in multiple system atrophy: clinicopathological correlations

scientific article published on 27 October 2004

Clinical and neuroanatomical signatures of tissue pathology in frontotemporal lobar degeneration

scientific article

α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson's disease and multiple system atrophy?

scientific article published on 12 February 2013

Mutations in the gene LRRK2 encoding dardarin (PARK8) cause familial Parkinson's disease: clinical, pathological, olfactory and functional imaging and genetic data

scientific article

Research in motion: the enigma of Parkinson's disease pathology spread

scientific article published on 04 September 2008

A decamer duplication in the 3' region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred

scientific article

Does corticobasal degeneration exist? A clinicopathological re-evaluation

scientific article published on July 2010

Cerebral amyloid angiopathies: a pathologic, biochemical, and genetic view

scientific article

Relationships between age and late progression of Parkinson's disease: a clinico-pathological study

scientific article published on 5 April 2010

Pathological tau burden and distribution distinguishes progressive supranuclear palsy-parkinsonism from Richardson's syndrome

scientific article

Clinical outcomes of progressive supranuclear palsy and multiple system atrophy

scientific article

FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration

scientific article

Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies

scientific article

A distinct clinical, neuropsychological and radiological phenotype is associated with progranulin gene mutations in a large UK series

scientific article published on 29 January 2008

The neuropathology, pathophysiology and genetics of multiple system atrophy

scientific article published on February 1, 2012

Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress

scientific article published on July 2006

Neurofilament inclusion body disease: a new proteinopathy?

scientific article published on 22 July 2003

C9orf72 expansions in frontotemporal dementia and amyotrophic lateral sclerosis

scientific article

Widespread Lewy body and tau accumulation in childhood and adult onset dystonia-parkinsonism cases with PLA2G6 mutations

scientific article published on 21 July 2010

Mutations in TTBK2, encoding a kinase implicated in tau phosphorylation, segregate with spinocerebellar ataxia type 11.

scientific article

Alpha‐synuclein mRNA expression in oligodendrocytes in MSA

scientific article published on March 3, 2014

Pure akinesia with gait freezing: a third clinical phenotype of progressive supranuclear palsy

scientific article

Magnetic resonance imaging signatures of tissue pathology in frontotemporal dementia

scientific article

Degeneration in different parkinsonian syndromes relates to astrocyte type and astrocyte protein expression

scientific article published in October 2009

Gene expression in Huntington's disease skeletal muscle: a potential biomarker

scientific article published on 11 May 2005

The novel Parkinson's disease linked mutation G51D attenuates in vitro aggregation and membrane binding of α-synuclein, and enhances its secretion and nuclear localization in cells.

scientific article

Globular glial tauopathies (GGT): consensus recommendations

scientific article published on 31 August 2013

Cortical alpha-synuclein load is associated with amyloid-beta plaque burden in a subset of Parkinson's disease patients

scientific article published on 08 January 2008

Dysregulation of glucose metabolism is an early event in sporadic Parkinson's disease

scientific article published on November 9, 2013

Frontotemporal lobar degeneration and ubiquitin immunohistochemistry

scientific article published on 01 August 2004

Familial Danish dementia: a novel form of cerebral amyloidosis associated with deposition of both amyloid-Dan and amyloid-beta

scientific article published in March 2002

Regional distribution of amyloid-Bri deposition and its association with neurofibrillary degeneration in familial British dementia

scientific article

Conventional magnetic resonance imaging in confirmed progressive supranuclear palsy and multiple system atrophy

scientific article published on 04 April 2012

Sporadic and familial cerebral amyloid angiopathies.

scientific article

Cognitive impairment in multiple system atrophy: a position statement by the Neuropsychology Task Force of the MDS Multiple System Atrophy (MODIMSA) study group

scientific article

Regional differences in the severity of Lewy body pathology across the olfactory cortex

scientific article

An immunohistochemical study of cases of sporadic and inherited frontotemporal lobar degeneration using 3R- and 4R-specific tau monoclonal antibodies

scientific article published on 22 March 2006

A multidisciplinary team approach to skull base chordomas

scientific article published on August 1, 2001

Adenosine monophosphate-activated protein kinase disease mimicks hypertrophic cardiomyopathy and Wolff-Parkinson-White syndrome: natural history

scientific article published in March 2005

International consensus on a proposed score system for muscle biopsy evaluation in patients with juvenile dermatomyositis: a tool for potential use in clinical trials.

scientific article published on October 2007

Variant Alzheimer's disease with spastic paraparesis and cotton wool plaques is caused by PS-1 mutations that lead to exceptionally high amyloid-beta concentrations

scientific article published on 01 November 2000

List of works by Janice Holton

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease

A common LRRK2 mutation in idiopathic Parkinson's disease

Lewy- and Alzheimer-type pathologies in Parkinson's disease dementia: which is more important?

Characteristics of two distinct clinical phenotypes in pathologically proven progressive supranuclear palsy: Richardson's syndrome and PSP-parkinsonism

PINK1 protein in normal human brain and Parkinson's disease

A clinico-pathological study of subtypes in Parkinson's disease

Neuropathology underlying clinical variability in patients with synucleinopathies

SNCA variants are associated with increased risk for multiple system atrophy

The spectrum of pathological involvement of the striatonigral and olivopontocerebellar systems in multiple system atrophy: clinicopathological correlations

Clinical and neuroanatomical signatures of tissue pathology in frontotemporal lobar degeneration

α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson's disease and multiple system atrophy?

Mutations in the gene LRRK2 encoding dardarin (PARK8) cause familial Parkinson's disease: clinical, pathological, olfactory and functional imaging and genetic data

Research in motion: the enigma of Parkinson's disease pathology spread

A decamer duplication in the 3' region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred

Does corticobasal degeneration exist? A clinicopathological re-evaluation

Cerebral amyloid angiopathies: a pathologic, biochemical, and genetic view

Relationships between age and late progression of Parkinson's disease: a clinico-pathological study

Pathological tau burden and distribution distinguishes progressive supranuclear palsy-parkinsonism from Richardson's syndrome

Clinical outcomes of progressive supranuclear palsy and multiple system atrophy

FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration

Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies

A distinct clinical, neuropsychological and radiological phenotype is associated with progranulin gene mutations in a large UK series

The neuropathology, pathophysiology and genetics of multiple system atrophy

Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress

Neurofilament inclusion body disease: a new proteinopathy?

C9orf72 expansions in frontotemporal dementia and amyotrophic lateral sclerosis

Widespread Lewy body and tau accumulation in childhood and adult onset dystonia-parkinsonism cases with PLA2G6 mutations

Mutations in TTBK2, encoding a kinase implicated in tau phosphorylation, segregate with spinocerebellar ataxia type 11.

Alpha‐synuclein mRNA expression in oligodendrocytes in MSA

Pure akinesia with gait freezing: a third clinical phenotype of progressive supranuclear palsy

Magnetic resonance imaging signatures of tissue pathology in frontotemporal dementia

Degeneration in different parkinsonian syndromes relates to astrocyte type and astrocyte protein expression

Gene expression in Huntington's disease skeletal muscle: a potential biomarker

The novel Parkinson's disease linked mutation G51D attenuates in vitro aggregation and membrane binding of α-synuclein, and enhances its secretion and nuclear localization in cells.

Globular glial tauopathies (GGT): consensus recommendations

Cortical alpha-synuclein load is associated with amyloid-beta plaque burden in a subset of Parkinson's disease patients

Dysregulation of glucose metabolism is an early event in sporadic Parkinson's disease

Frontotemporal lobar degeneration and ubiquitin immunohistochemistry

Familial Danish dementia: a novel form of cerebral amyloidosis associated with deposition of both amyloid-Dan and amyloid-beta

Regional distribution of amyloid-Bri deposition and its association with neurofibrillary degeneration in familial British dementia

Conventional magnetic resonance imaging in confirmed progressive supranuclear palsy and multiple system atrophy

Sporadic and familial cerebral amyloid angiopathies.

Cognitive impairment in multiple system atrophy: a position statement by the Neuropsychology Task Force of the MDS Multiple System Atrophy (MODIMSA) study group

Regional differences in the severity of Lewy body pathology across the olfactory cortex

An immunohistochemical study of cases of sporadic and inherited frontotemporal lobar degeneration using 3R- and 4R-specific tau monoclonal antibodies

A multidisciplinary team approach to skull base chordomas

Adenosine monophosphate-activated protein kinase disease mimicks hypertrophic cardiomyopathy and Wolff-Parkinson-White syndrome: natural history

International consensus on a proposed score system for muscle biopsy evaluation in patients with juvenile dermatomyositis: a tool for potential use in clinical trials.

Variant Alzheimer's disease with spastic paraparesis and cotton wool plaques is caused by PS-1 mutations that lead to exceptionally high amyloid-beta concentrations