List of works - George Kirov

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

scientific article

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

scientific article

Rare chromosomal deletions and duplications increase risk of schizophrenia

scientific article

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

scientific article

De novo mutations in schizophrenia implicate synaptic networks

scientific article

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

scientific article

Identification of loci associated with schizophrenia by genome-wide association and follow-up

scientific article

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

scientific article

De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia.

scientific article

Microduplications of 16p11.2 are associated with schizophrenia

scientific article

Discovery and statistical genotyping of copy-number variation from whole-exome sequencing depth

scientific article

Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus. Brain-derived neutrophic factor

scientific article

The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia

scientific article

Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia

scientific article

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

scientific article

Support for the involvement of large copy number variants in the pathogenesis of schizophrenia

scientific article published on 29 January 2009

Analysis of copy number variations at 15 schizophrenia-associated loci.

scientific article published on 05 December 2013

Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder

scientific article published on 06 April 2010

Genome-wide association study identifies 30 loci associated with bipolar disorder.

scientific article

Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders.

scientific article

Neurexin 1 (NRXN1) deletions in schizophrenia

scientific article

Copy number variation in schizophrenia in Sweden

scientific article

The penetrance of copy number variations for schizophrenia and developmental delay.

scientific article

Meta-analysis of studies on genetic variation in 5-HT2A receptors and clozapine response

scientific article published in July 1998

Operation of the schizophrenia susceptibility gene, neuregulin 1, across traditional diagnostic boundaries to increase risk for bipolar disorder

scientific article published in June 2005

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

article

Rare copy number variants: a point of rarity in genetic risk for bipolar disorder and schizophrenia

scientific article published on April 2010

Evidence that interaction between neuregulin 1 and its receptor erbB4 increases susceptibility to schizophrenia

scientific article

Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.

scientific article

Genomewide Linkage Scan in Schizoaffective Disorder

scientific article published on 01 October 2005

Identification in 2 independent samples of a novel schizophrenia risk haplotype of the dystrobrevin binding protein gene (DTNBP1).

scientific article

Universal, robust, highly quantitative SNP allele frequency measurement in DNA pools

scientific article published on 23 March 2002

Cheap, accurate and rapid allele frequency estimation of single nucleotide polymorphisms by primer extension and DHPLC in DNA pools

scientific article published on 01 November 2000

A comprehensive family-based replication study of schizophrenia genes

scientific article

A genome-wide association study in 574 schizophrenia trios using DNA pooling

scientific journal article

Strong evidence for association between the dystrobrevin binding protein 1 gene (DTNBP1) and schizophrenia in 488 parent-offspring trios from Bulgaria

scientific article

Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype

scientific article

A network of dopaminergic gene variations implicated as risk factors for schizophrenia

scientific article

Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain

scientific article published on February 22, 2011

Copy number variation in schizophrenia in the Japanese population

scientific article

Support for RGS4 as a susceptibility gene for schizophrenia

scientific article

Novel Findings from CNVs Implicate Inhibitory and Excitatory Signaling Complexes in Schizophrenia

scientific article

Copy number variation in bipolar disorder

scientific article published on 06 January 2015

Support for neuregulin 1 as a susceptibility gene for bipolar disorder and schizophrenia

scientific article published on 7 May 2008

Analysis of a structural polymorphism in the 5-HT2A receptor and clinical response to clozapine

article

Convergent evidence that oligodendrocyte lineage transcription factor 2 (OLIG2) and interacting genes influence susceptibility to schizophrenia

scientific article

Evidence that duplications of 22q11.2 protect against schizophrenia

scientific article

Rare exonic deletions implicate the synaptic organizer Gephyrin (GPHN) in risk for autism, schizophrenia and seizures

scientific article published on 7 February 2013

Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample

scientific article published on 16 October 2012

Pooled DNA genotyping on Affymetrix SNP genotyping arrays

scientific article

List of works by George Kirov

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Rare chromosomal deletions and duplications increase risk of schizophrenia

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

De novo mutations in schizophrenia implicate synaptic networks

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

Identification of loci associated with schizophrenia by genome-wide association and follow-up

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia.

Microduplications of 16p11.2 are associated with schizophrenia

Discovery and statistical genotyping of copy-number variation from whole-exome sequencing depth

Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus. Brain-derived neutrophic factor

The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia

Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Support for the involvement of large copy number variants in the pathogenesis of schizophrenia

Analysis of copy number variations at 15 schizophrenia-associated loci.

Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder

Genome-wide association study identifies 30 loci associated with bipolar disorder.

Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders.

Neurexin 1 (NRXN1) deletions in schizophrenia

Copy number variation in schizophrenia in Sweden

The penetrance of copy number variations for schizophrenia and developmental delay.

Meta-analysis of studies on genetic variation in 5-HT2A receptors and clozapine response

Operation of the schizophrenia susceptibility gene, neuregulin 1, across traditional diagnostic boundaries to increase risk for bipolar disorder

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Rare copy number variants: a point of rarity in genetic risk for bipolar disorder and schizophrenia

Evidence that interaction between neuregulin 1 and its receptor erbB4 increases susceptibility to schizophrenia

Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.

Genomewide Linkage Scan in Schizoaffective Disorder

Identification in 2 independent samples of a novel schizophrenia risk haplotype of the dystrobrevin binding protein gene (DTNBP1).

Universal, robust, highly quantitative SNP allele frequency measurement in DNA pools

Cheap, accurate and rapid allele frequency estimation of single nucleotide polymorphisms by primer extension and DHPLC in DNA pools

A comprehensive family-based replication study of schizophrenia genes

A genome-wide association study in 574 schizophrenia trios using DNA pooling

Strong evidence for association between the dystrobrevin binding protein 1 gene (DTNBP1) and schizophrenia in 488 parent-offspring trios from Bulgaria

Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype

A network of dopaminergic gene variations implicated as risk factors for schizophrenia

Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain

Copy number variation in schizophrenia in the Japanese population

Support for RGS4 as a susceptibility gene for schizophrenia

Novel Findings from CNVs Implicate Inhibitory and Excitatory Signaling Complexes in Schizophrenia

Copy number variation in bipolar disorder

Support for neuregulin 1 as a susceptibility gene for bipolar disorder and schizophrenia

Analysis of a structural polymorphism in the 5-HT2A receptor and clinical response to clozapine

Convergent evidence that oligodendrocyte lineage transcription factor 2 (OLIG2) and interacting genes influence susceptibility to schizophrenia

Evidence that duplications of 22q11.2 protect against schizophrenia

Rare exonic deletions implicate the synaptic organizer Gephyrin (GPHN) in risk for autism, schizophrenia and seizures

Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample

Pooled DNA genotyping on Affymetrix SNP genotyping arrays