List of works - Mark Caulfield

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

scientific article

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).

scientific article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial--Lipid Lowering Arm (ASCOT-LLA): a multicentre ra

scientific article

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

scientific article

Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (A

scientific article

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

scientific article

Common variants near MC4R are associated with fat mass, weight and risk of obesity

scientific article

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

scientific article

Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document

article by Giuseppe Mancia et al published November 2009 in Journal of Hypertension

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

scientific article

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

scientific article

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

scientific article published in June 2009

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

scientific article published in February 2013

Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people

scientific article

Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies

scientific article

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

scientific article published in June 2009

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci

scientific article

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

scientific article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia

scientific article

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

scientific article published on 16 October 2011

Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial

scientific article

Bayesian refinement of association signals for 14 loci in 3 common diseases

scientific article published on 28 October 2012

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

scientific article

Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension

scientific article

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

scientific article

Linkage of the Angiotensinogen Gene to Essential Hypertension

article

Management of hypertension: summary of NICE guidance

scientific article published on August 25, 2011

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci

scientific article

Genetic loci influencing kidney function and chronic kidney disease

scientific article

Hypertension

scientific article published in The Lancet

SLC2A9 is a high-capacity urate transporter in humans

scientific article

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci

scientific article

KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron

scientific article

Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials

scientific article

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

scientific article published on 14 April 2013

Dietary nitrate provides sustained blood pressure lowering in hypertensive patients: a randomized, phase 2, double-blind, placebo-controlled study

scientific article

Cost-effectiveness of options for the diagnosis of high blood pressure in primary care: a modelling study

scientific article

Role of blood pressure and other variables in the differential cardiovascular event rates noted in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA).

scientific article

List of works by Mark Caulfield

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

Biological, clinical and population relevance of 95 loci for blood lipids

2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).

Genetic studies of body mass index yield new insights for obesity biology

Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial--Lipid Lowering Arm (ASCOT-LLA): a multicentre ra

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (A

Defining the role of common variation in the genomic and biological architecture of adult human height

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

Common variants near MC4R are associated with fat mass, weight and risk of obesity

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

New genetic loci link adipose and insulin biology to body fat distribution

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people

Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial

Bayesian refinement of association signals for 14 loci in 3 common diseases

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

Linkage of the Angiotensinogen Gene to Essential Hypertension

Management of hypertension: summary of NICE guidance

Rare and low-frequency coding variants alter human adult height

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci

Genetic loci influencing kidney function and chronic kidney disease

Hypertension

SLC2A9 is a high-capacity urate transporter in humans

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci

KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron

Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

Dietary nitrate provides sustained blood pressure lowering in hypertensive patients: a randomized, phase 2, double-blind, placebo-controlled study

Cost-effectiveness of options for the diagnosis of high blood pressure in primary care: a modelling study

Role of blood pressure and other variables in the differential cardiovascular event rates noted in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA).