List of works - Alena Stančáková

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Discovery and refinement of loci associated with lipid levels

scientific article

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

scientific article

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

scientific article published on 13 May 2012

The genetic architecture of type 2 diabetes

scientific article (publication date: 11 July 2016)

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome

scientific article

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children

scientific article

Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion

scientific article

Changes in insulin sensitivity and insulin release in relation to glycemia and glucose tolerance in 6,414 Finnish men

scientific article published on 17 February 2009

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

scientific article

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity

scientific article

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

scientific article

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

scientific article published on 08 October 2018

Hyperglycemia and a common variant of GCKR are associated with the levels of eight amino acids in 9,369 Finnish men

scientific article

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits

scientific journal article

Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry

scientific article

Increased risk of diabetes with statin treatment is associated with impaired insulin sensitivity and insulin secretion: a 6 year follow-up study of the METSIM cohort

scientific article published on 10 March 2015

Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men.

scientific article published on 05 June 2009

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

scientific article published on 12 September 2016

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

scientific article

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

scientific article published on February 2016

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

scientific article published on 14 January 2019

Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes.

scientific article published on 19 November 2012

Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained

scientific article

Directional dominance on stature and cognition in diverse human populations

scientific article published in July 2015

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

scientific article published on 9 April 2018

Relation of direct and surrogate measures of insulin resistance to cardiovascular risk factors in nondiabetic finnish offspring of type 2 diabetic individuals

scientific article published on 11 August 2010

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

scientific article

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 27 April 2017

Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance

scientific article

Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits

scientific article

A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes

scientific article published on January 2011

The Metabolic Syndrome in Men study: a resource for studies of metabolic and cardiovascular diseases

scientific article published on 24 January 2017

Pleiotropic effects of GIP on islet function involve osteopontin

scientific article

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

scientific article

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

scientific article published on June 2016

Association of ketone body levels with hyperglycemia and type 2 diabetes in 9,398 Finnish men.

scientific article published on 04 April 2013

Effects of 34 risk loci for type 2 diabetes or hyperglycemia on lipoprotein subclasses and their composition in 6,580 nondiabetic Finnish men.

scientific article published on 18 March 2011

A candidate type 2 diabetes polymorphism near the HHEX locus affects acute glucose-stimulated insulin release in European populations: results from the EUGENE2 study

scientific article published on 26 November 2007

Association of erythrocyte membrane fatty acids with changes in glycemia and risk of type 2 diabetes

scientific article

A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

scientific article published on 10 May 2017

Plasma fatty acids as predictors of glycaemia and type 2 diabetes

scientific article published on 16 August 2015

List of works by Alena Stančáková

Genetic studies of body mass index yield new insights for obesity biology

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Discovery and refinement of loci associated with lipid levels

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

Defining the role of common variation in the genomic and biological architecture of adult human height

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

New genetic loci link adipose and insulin biology to body fat distribution

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

The genetic architecture of type 2 diabetes

Common variants associated with plasma triglycerides and risk for coronary artery disease

SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children

Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion

Changes in insulin sensitivity and insulin release in relation to glycemia and glucose tolerance in 6,414 Finnish men

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

Hyperglycemia and a common variant of GCKR are associated with the levels of eight amino acids in 9,369 Finnish men

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits

Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry

Increased risk of diabetes with statin treatment is associated with impaired insulin sensitivity and insulin secretion: a 6 year follow-up study of the METSIM cohort

Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men.

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes.

Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained

Directional dominance on stature and cognition in diverse human populations

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

Relation of direct and surrogate measures of insulin resistance to cardiovascular risk factors in nondiabetic finnish offspring of type 2 diabetic individuals

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance

Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits

A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes

The Metabolic Syndrome in Men study: a resource for studies of metabolic and cardiovascular diseases

Pleiotropic effects of GIP on islet function involve osteopontin

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

Association of ketone body levels with hyperglycemia and type 2 diabetes in 9,398 Finnish men.

Effects of 34 risk loci for type 2 diabetes or hyperglycemia on lipoprotein subclasses and their composition in 6,580 nondiabetic Finnish men.

A candidate type 2 diabetes polymorphism near the HHEX locus affects acute glucose-stimulated insulin release in European populations: results from the EUGENE2 study

Association of erythrocyte membrane fatty acids with changes in glycemia and risk of type 2 diabetes

A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

Plasma fatty acids as predictors of glycaemia and type 2 diabetes