List of works - Johan Auwerx

Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

scientific article

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

scientific article

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

scientific article

Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

scientific article

Sirtuins as regulators of metabolism and healthspan

scientific article

Mechanism of action of fibrates on lipid and lipoprotein metabolism

scientific article

TGR5-mediated bile acid sensing controls glucose homeostasis

scientific article

The organization, promoter analysis, and expression of the human PPARgamma gene

scientific article (publication date: 25 July 1997)

A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

scientific article

PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

scientific article published on April 2009

Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase

scientific article

Transient increase in obese gene expression after food intake or insulin administration

scientific article

Targeting bile-acid signalling for metabolic diseases

scientific article published on August 2008

Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

scientific article

Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c

scientific article

The peroxisome proliferator activated receptors (PPARS) and their effects on lipid metabolism and adipocyte differentiation

scientific article published on July 1996

International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors

scientific article

Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle

scientific article published on March 2010

The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity

scientific article published on June 2012

Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β

scientific article by H. Cho et al., published in March 2012

Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation

scientific article

Mitonuclear protein imbalance as a conserved longevity mechanism

scientific article published on May 2013

The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

scientific article

The secret life of NAD+: an old metabolite controlling new metabolic signaling pathways

scientific article

Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis

scientific article published on 02 February 2011

A guide to analysis of mouse energy metabolism

scientific article published on 28 December 2011

Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism

scientific article

Expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein

scientific article published on June 1998

PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene

scientific article

Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration

scientific article published on November 2008

NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

scientific article published on 25 June 2015

NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice

scientific article

Nuclear receptors and the control of metabolism

scientific article

Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: no alteration in adipose tissue of obese and NIDDM patients

scientific article

Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression

scientific article

Endocrine functions of bile acids

scientific article

Systems proteomics of liver mitochondria function

scientific article

Sirtuins: the 'magnificent seven', function, metabolism and longevity

scientific article published on January 2007

Coordinate regulation of the expression of the fatty acid transport protein and acyl-CoA synthetase genes by PPARalpha and PPARgamma activators

scientific article published on November 1997

Attenuation of colon inflammation through activators of the retinoid X receptor (RXR)/peroxisome proliferator-activated receptor gamma (PPARgamma) heterodimer. A basis for new therapeutic strategies

scientific article

Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma

scientific article

Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor alpha-deficient mice

scientific article published on October 1997

Induction of ob gene expression by corticosteroids is accompanied by body weight loss and reduced food intake

scientific article

Impaired expression of peroxisome proliferator-activated receptor gamma in ulcerative colitis

scientific article published in May 2003

Sirtuin functions in health and disease

scientific article

Multilayered genetic and omics dissection of mitochondrial activity in a mouse reference population

scientific article

Caloric restriction, SIRT1 and longevity

scientific article published on 25 August 2009

Mature-onset obesity and insulin resistance in mice deficient in the signaling adapter p62.

scientific article

Fibrates increase human apolipoprotein A-II expression through activation of the peroxisome proliferator-activated receptor

scientific article published on August 1995

Regulation of peroxisome proliferator-activated receptor gamma expression by adipocyte differentiation and determination factor 1/sterol regulatory element binding protein 1: implications for adipocyte differentiation and metabolism

scientific article

List of works by Johan Auwerx

Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

Sirtuins as regulators of metabolism and healthspan

Mechanism of action of fibrates on lipid and lipoprotein metabolism

TGR5-mediated bile acid sensing controls glucose homeostasis

The organization, promoter analysis, and expression of the human PPARgamma gene

A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase

Transient increase in obese gene expression after food intake or insulin administration

Targeting bile-acid signalling for metabolic diseases

Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c

The peroxisome proliferator activated receptors (PPARS) and their effects on lipid metabolism and adipocyte differentiation

International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors

Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle

The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity

Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β

Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation

Mitonuclear protein imbalance as a conserved longevity mechanism

The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

The secret life of NAD+: an old metabolite controlling new metabolic signaling pathways

Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis

A guide to analysis of mouse energy metabolism

Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism

Expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein

PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene

Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration

NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice

Nuclear receptors and the control of metabolism

Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: no alteration in adipose tissue of obese and NIDDM patients

Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression

Endocrine functions of bile acids

Systems proteomics of liver mitochondria function

Sirtuins: the 'magnificent seven', function, metabolism and longevity

Coordinate regulation of the expression of the fatty acid transport protein and acyl-CoA synthetase genes by PPARalpha and PPARgamma activators

Attenuation of colon inflammation through activators of the retinoid X receptor (RXR)/peroxisome proliferator-activated receptor gamma (PPARgamma) heterodimer. A basis for new therapeutic strategies

Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma

Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor alpha-deficient mice

Induction of ob gene expression by corticosteroids is accompanied by body weight loss and reduced food intake

Impaired expression of peroxisome proliferator-activated receptor gamma in ulcerative colitis

Sirtuin functions in health and disease

Multilayered genetic and omics dissection of mitochondrial activity in a mouse reference population

Caloric restriction, SIRT1 and longevity

Mature-onset obesity and insulin resistance in mice deficient in the signaling adapter p62.

Fibrates increase human apolipoprotein A-II expression through activation of the peroxisome proliferator-activated receptor

Regulation of peroxisome proliferator-activated receptor gamma expression by adipocyte differentiation and determination factor 1/sterol regulatory element binding protein 1: implications for adipocyte differentiation and metabolism